Targeting Autophagy-Related Epigenetic Regulators for Cancer Drug Discovery
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Title
Targeting Autophagy-Related Epigenetic Regulators for Cancer Drug Discovery
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 64, Issue 16, Pages 11798-11815
Publisher
American Chemical Society (ACS)
Online
2021-08-11
DOI
10.1021/acs.jmedchem.1c00579
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Note: Only part of the references are listed.- Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells
- (2021) Lanzhu Li et al. Oxidative Medicine and Cellular Longevity
- Targeting Bromodomain and Extraterminal Proteins for Drug Discovery: From Current Progress to Technological Development
- (2021) Pan Tang et al. JOURNAL OF MEDICINAL CHEMISTRY
- LSD1 contributes to programmed oocyte death by regulating the transcription of autophagy adaptor SQSTM1/p62
- (2020) Meina He et al. AGING CELL
- Downregulation of SETD7 promotes migration and invasion of lung cancer cells via JAK2/STAT3 pathway
- (2020) Limin Cao et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Inhibition of JNJ-26481585-mediated autophagy induces apoptosis via ROS activation and mitochondrial membrane potential disruption in neuroblastoma cells
- (2020) Vamsi Krishna Kommalapati et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Anti-leukemic effects of histone deacetylase (HDAC) inhibition in acute lymphoblastic leukemia (ALL) cells: Shedding light on mitigating effects of NF-κB and autophagy on panobinostat cytotoxicity
- (2020) Mahdieh Mehrpouri et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy
- (2020) Tingting Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii
- (2020) Lan-Bi Nie et al. Frontiers in Microbiology
- The multi-kinase inhibitor lenvatinib interacts with the HDAC inhibitor entinostat to kill liver cancer cells
- (2020) Jane L. Roberts et al. CELLULAR SIGNALLING
- Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight
- (2020) Terence C. S. Ho et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chidamide, a histone deacetylase inhibitor, inhibits autophagy and exhibits therapeutic implication in chronic lymphocytic leukemia
- (2020) Yi-Lin Kong et al. Aging-US
- Targeting Atg4B for cancer therapy: Chemical mediators
- (2020) Gaoxia Yang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The role of epigenetics and non-coding RNAs in autophagy: A new perspective for thorough understanding
- (2020) Shahrzad Talebian et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Scaffolding LSD1 Inhibitors Impair NK Cell Metabolism and Cytotoxic Function Through Depletion of Glutathione
- (2020) Cavan P. Bailey et al. Frontiers in Immunology
- Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival
- (2019) Giorgia Foggetti et al. BIOSCIENCE REPORTS
- High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma
- (2019) Jia-Rong Liu et al. BIOCHEMICAL PHARMACOLOGY
- Type I and II PRMTs regulate catabolic as well as detoxifying processes in Aspergillus nidulans
- (2019) Ingo Bauer et al. FUNGAL GENETICS AND BIOLOGY
- EZH2 inhibition suppresses bladder cancer cell growth and metastasis via the JAK2/STAT3 signaling pathway
- (2019) Zhiyuan Chen et al. Oncology Letters
- Targeting autophagy-related protein kinases for potential therapeutic purpose
- (2019) Honggang Xiang et al. Acta Pharmaceutica Sinica B
- Epigenetic Control of Autophagy in Cancer Cells: A Key Process for Cancer-Related Phenotypes
- (2019) Paul Peixoto et al. Cells
- Crosstalk between lysine methylation and phosphorylation of ATG16L1 dictates the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes
- (2018) Huiwen Song et al. Autophagy
- HIF1A is Overexpressed in Medulloblastoma and its Inhibition Reduces Proliferation and Increases EPAS1 and ATG16L1 Methylation
- (2018) Gustavo Alencastro Veiga Cruzeiro et al. CURRENT CANCER DRUG TARGETS
- Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson’s Disease Treatment
- (2018) Liang Ouyang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Histone Methyltransferase Setd7 Regulates Nrf2 Signaling Pathway by Phenethyl Isothiocyanate and Ursolic Acid in Human Prostate Cancer Cells
- (2018) Chao Wang et al. MOLECULAR NUTRITION & FOOD RESEARCH
- LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy
- (2018) Changhong Liu et al. MOLECULAR THERAPY
- Metastatic prostate cancer-associated P62 inhibits autophagy flux and promotes epithelial to mesenchymal transition by sustaining the level of HDAC6
- (2018) Xianhan Jiang et al. PROSTATE
- Targeting the miR-665-3p-ATG4B-autophagy axis relieves inflammation and apoptosis in intestinal ischemia/reperfusion
- (2018) Zhenlu Li et al. Cell Death & Disease
- Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment
- (2018) Jianbo Feng et al. ONCOGENE
- NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation
- (2018) Ji Hye Shin et al. Oncogenesis
- microRNAs-107 inhibited autophagy, proliferation, and migration of breast cancer cells by targeting HMGB1
- (2018) Hongyan Ai et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer
- (2018) Keqiang Zhang et al. Molecular Cancer
- Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells
- (2018) Youping Yang et al. OncoTargets and Therapy
- EZH2 inhibitors: a patent review (2014-2016)
- (2017) Giulia Stazi et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Autophagy impairment byHelicobacter pylori-induced methylation silencing ofMAP1LC3Av1promotes gastric carcinogenesis
- (2017) Jibran Sualeh Muhammad et al. INTERNATIONAL JOURNAL OF CANCER
- Let-7i-Induced Atg4B Suppression Is Essential for Autophagy of Placental Trophoblast in Preeclampsia
- (2017) Yinyan Xu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer
- (2017) Liang Ouyang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Histone deacetylase 7 silencing induces apoptosis and autophagy in salivary mucoepidermoid carcinoma cells
- (2017) Mee-Young Ahn et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
- (2017) Jun-ichi Sakamaki et al. MOLECULAR CELL
- Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway
- (2017) S Ambrosio et al. ONCOGENE
- MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability
- (2017) L Liu et al. ONCOGENE
- Downregulation of miRNA-26b inhibits cancer proliferation of laryngeal carcinoma through autophagy by targeting ULK2 and inactivation of the PTEN/AKT pathway
- (2017) Shujing Wang et al. ONCOLOGY REPORTS
- MicroRNA-144-3p inhibits autophagy activation and enhances Bacillus Calmette-Guérin infection by targeting ATG4a in RAW264.7 macrophage cells
- (2017) Le Guo et al. PLoS One
- Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis
- (2017) Rui Zhang et al. TUMOR BIOLOGY
- Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo
- (2017) Lan Zhang et al. Chemical Science
- MicroRNA-18a-5p functions as an oncogene by directly targeting IRF2 in lung cancer
- (2017) Chen Liang et al. Cell Death & Disease
- Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies
- (2017) Angel Chao et al. Oncotarget
- TUSC3 induces autophagy in human non-small cell lung cancer cells through Wnt/β-catenin signaling
- (2017) Yun Peng et al. Oncotarget
- Promoter methylation of TCF21 may repress autophagy in the progression of lung cancer
- (2017) Baokun Chen et al. Journal of Cell Communication and Signaling
- Targeting the MIR34C-5p-ATG4B-autophagy axis enhances the sensitivity of cervical cancer cells to pirarubicin
- (2016) Yaran Wu et al. Autophagy
- 3,3′-Diindolylmethane induces anti-human gastric cancer cells by the miR-30e-ATG5 modulating autophagy
- (2016) Yang Ye et al. BIOCHEMICAL PHARMACOLOGY
- CARM1 Preferentially Methylates H3R17 over H3R26 through a Random Kinetic Mechanism
- (2016) Suzanne L. Jacques et al. BIOCHEMISTRY
- Upregulation of p72 enhances malignant migration and invasion of glioma cells by repressing Beclin1 expression
- (2016) Zhenxing Zhang et al. BIOCHEMISTRY-MOSCOW
- Cyproheptadine exhibits antitumor activity in urothelial carcinoma cells by targeting GSK3β to suppress mTOR and β-catenin signaling pathways
- (2016) Hsiao-Yen Hsieh et al. CANCER LETTERS
- AMPK–ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells
- (2016) Ji Eun Jang et al. CLINICAL CANCER RESEARCH
- SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling
- (2016) Menno J. Oudhoff et al. DEVELOPMENTAL CELL
- Aberrant methylation of ATG2B , ATG4D , ATG9A and ATG9B CpG island promoter is associated with decreased mRNA expression in sporadic breast carcinoma
- (2016) Xuemei Zhang et al. GENE
- Reversine Increases the Plasticity of Long-Term Cryopreserved Fibroblasts to Multipotent Progenitor Cells through Activation of Oct4
- (2016) Xiangchen Li et al. International Journal of Biological Sciences
- Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription
- (2016) Yasushi Takemoto et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure
- (2016) Edward Ratovitski Marine Drugs
- AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy
- (2016) Hi-Jai R. Shin et al. NATURE
- Histone deacetylase 8 as a novel therapeutic target in oral squamous cell carcinoma
- (2016) Mee-Young Ahn et al. ONCOLOGY REPORTS
- Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB
- (2016) Sang Eun Park et al. Oncotarget
- Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells
- (2016) Francesca Angeletti et al. Frontiers in Molecular Neuroscience
- Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells
- (2016) Jane Ying-Chieh Lee et al. Frontiers in Pharmacology
- Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells
- (2016) Yizhou Yao et al. Genes
- S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells
- (2015) Tsang-Pai Liu et al. ANTI-CANCER DRUGS
- Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway
- (2015) Fu-Zheng Wei et al. Autophagy
- Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways
- (2015) Jianbin Zhang et al. Autophagy
- Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinoma
- (2015) Aishu Ren et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation
- (2015) Rui Huang et al. MOLECULAR CELL
- MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells
- (2015) Xing Guo et al. Oncotarget
- miR-340 suppresses glioblastoma multiforme
- (2015) Daquan Huang et al. Oncotarget
- BTG1 expression correlates with pathogenesis, aggressive behaviors and prognosis of gastric cancer: a potential target for gene therapy
- (2015) Hua-chuan Zheng et al. Oncotarget
- The roles of BTG3 expression in gastric cancer: a potential marker for carcinogenesis and a target molecule for gene therapy
- (2015) Wen-feng Gou et al. Oncotarget
- Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib
- (2015) Kwai Fung Hui et al. Oncotarget
- miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG
- (2015) Longtao Huangfu et al. Oncotarget
- miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy
- (2015) Animesh Bhattacharya et al. Oncotarget
- The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death
- (2015) Jia-Dong Fan et al. PLoS One
- Mir-24-3p downregulation contributes to VP16–DDP resistance in small-cell lung cancer by targeting ATG4A
- (2015) Banzhou Pan et al. Oncotarget
- Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells
- (2014) Hua Zhu et al. Autophagy
- YY1-MIR372-SQSTM1 regulatory axis in autophagy
- (2014) Lifeng Feng et al. Autophagy
- EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells
- (2014) Bryson W Katona et al. CANCER BIOLOGY & THERAPY
- Methylation Silencing of ULK2, an Autophagy Gene, Is Essential for Astrocyte Transformation and Tumor Growth
- (2014) Sudhanshu Shukla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia
- (2014) V El-Khoury et al. LEUKEMIA
- miR-143 inhibits cell proliferation by targeting autophagy-related 2B in non-small cell lung cancer H1299 cells
- (2014) JIALI WEI et al. Molecular Medicine Reports
- Inhibition of H3K9 Methyltransferase G9a Repressed Cell Proliferation and Induced Autophagy in Neuroblastoma Cells
- (2014) Xiao-Xue Ke et al. PLoS One
- An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1
- (2013) Kyle D. Konze et al. ACS Chemical Biology
- CARM1 and PRMT1 are dysregulated in lung cancer without hierarchical features
- (2013) Rania Elakoum et al. BIOCHIMIE
- Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer
- (2013) Biao Xie et al. Cancer Cell International
- A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors
- (2013) M New et al. CELL DEATH AND DIFFERENTIATION
- Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients
- (2013) Yu-Ping Liao et al. HUMAN MOLECULAR GENETICS
- Epigenetic Regulation of Autophagy by the Methyltransferase G9a
- (2013) A. Artal-Martinez de Narvajas et al. MOLECULAR AND CELLULAR BIOLOGY
- The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
- (2013) Jens Füllgrabe et al. NATURE
- Role of Histone Lysine Methyltransferases SUV39H1 and SETDB1 in Gliomagenesis: Modulation of Cell Proliferation, Migration, and Colony Formation
- (2013) Anastasia Spyropoulou et al. NEUROMOLECULAR MEDICINE
- miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells
- (2013) YONGHUA XU et al. ONCOLOGY REPORTS
- Paradoxical Regulation of Hypoxia Inducible Factor-1α (HIF-1α) by Histone Deacetylase Inhibitor in Diffuse Large B-Cell Lymphoma
- (2013) Savita Bhalla et al. PLoS One
- Histone deacetylase 10 promotes autophagy-mediated cell survival
- (2013) I. Oehme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Down-Regulation of Autophagy-Related Protein 5 (ATG5) Contributes to the Pathogenesis of Early-Stage Cutaneous Melanoma
- (2013) H. Liu et al. Science Translational Medicine
- Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma
- (2013) N Syed et al. Cell Death & Disease
- Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress
- (2013) Pei-Ming Yang et al. Scientific Reports
- Pharmacokinetic and pharmacodynamic analysis of 5-aza-2’-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy
- (2013) Metin Karahoca et al. Clinical Epigenetics
- miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1
- (2012) Gozde Korkmaz et al. Autophagy
- VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma
- (2012) Olga Mikhaylova et al. CANCER CELL
- miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions
- (2012) Ying Chang et al. GASTROENTEROLOGY
- Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers
- (2012) Xiaotong Hu et al. JOURNAL OF PATHOLOGY
- EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
- (2012) Michael T. McCabe et al. NATURE
- HDAC1 Inactivation Induces Mitotic Defect and Caspase-Independent Autophagic Cell Death in Liver Cancer
- (2012) Hong Jian Xie et al. PLoS One
- Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
- (2012) M. T. McCabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
- (2012) J. G. Lohr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2
- (2012) Sharad K. Verma et al. ACS Medicinal Chemistry Letters
- The miR-290-295 cluster suppresses autophagic cell death of melanoma cells
- (2012) Yong Chen et al. Scientific Reports
- microRNA-101 is a potent inhibitor of autophagy
- (2011) Lisa B Frankel et al. EMBO JOURNAL
- The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells
- (2011) María J. Ruiz-Magaña et al. INTERNATIONAL JOURNAL OF CANCER
- Colorectal Cancer Epigenetics: Complex Simplicity
- (2011) Manon van Engeland et al. JOURNAL OF CLINICAL ONCOLOGY
- Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
- (2011) Ryan D. Morin et al. NATURE
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis
- (2010) I. Velichutina et al. BLOOD
- Genetic and epigenetic silencing of the beclin 1gene in sporadic breast tumors
- (2010) Zidong Li et al. BMC CANCER
- SET7/9 mediated methylation of non-histone proteins in mammalian cells
- (2010) Sriharsa Pradhan et al. Epigenetics
- Jarid2 and PRC2, partners in regulating gene expression
- (2010) G. Li et al. GENES & DEVELOPMENT
- G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53
- (2010) Jing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
- Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)—Hit to Lead studies
- (2009) Honghe Wan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- In VivoResidue-specific Histone Methylation Dynamics
- (2009) Barry M. Zee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein Arginine Methylation in Mammals: Who, What, and Why
- (2009) Mark T. Bedford et al. MOLECULAR CELL
- AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2
- (2009) Hana Kim et al. NUCLEIC ACIDS RESEARCH
- Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)
- (2008) Ashok V. Purandare et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
- (2008) Carlo Stresemann et al. INTERNATIONAL JOURNAL OF CANCER
- Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation
- (2008) Motonobu Watanabe et al. INTERNATIONAL JOURNAL OF CANCER
- Dominant Alleles Identify SET Domain Residues Required for Histone Methyltransferase of Polycomb Repressive Complex 2
- (2008) Preeti Joshi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms
- (2008) Raphael Margueron et al. MOLECULAR CELL
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