JOURNAL OF MEDICINAL CHEMISTRY

Journal Title
JOURNAL OF MEDICINAL CHEMISTRY

J. Med. Chem.

ISSN / eISSN
0022-2623 / 1520-4804
Aims and Scope
The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.

Some specific areas that are appropriate include the following:
Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools.
Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication.
Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds.
Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition.
Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge.
Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules.
Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs.
Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.
Subject Area

CHEMISTRY, MEDICINAL

CiteScore
12.30 View Trend
CiteScore Ranking
Category Quartile Rank
Pharmacology, Toxicology and Pharmaceutics - Drug Discovery Q1 #13/156
Pharmacology, Toxicology and Pharmaceutics - Molecular Medicine Q1 #18/171
Web of Science Core Collection
Science Citation Index Expanded (SCIE) Social Sciences Citation Index (SSCI)
Indexed -
Category (Journal Citation Reports 2023) Quartile
CHEMISTRY, MEDICINAL - SCIE Q1
H-index
240
Country/Area of Publication
UNITED STATES
Publisher
American Chemical Society
Publication Frequency
Biweekly
Year Publication Started
1959
Annual Article Volume
945
Open Access
NO
Contact
AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036
Verified Reviews
Note: Verified reviews are sourced from across review platforms and social media globally.
JMC is a top journal in the field of medicinal chemistry, representing the highest level in the field. I submitted an article and received the review results within a month, and it was accepted after the revision. The submission process for JMC is very simplified, without the need to upload high-resolution images, etc. The review speed is fast, with a response generally within three weeks. The reviewers are highly knowledgeable and provide constructive suggestions. Overall, JMC seems to prioritize innovative and comprehensive research results. This is my first article in JMC, and I hope to have more publications in the future. I also wish everyone success in their research!
2022-03-03
I also submitted it. The revision was due on September 20th, with four reviewers: one rejection, two minor revisions, and one major revision. We conducted additional experiments and made changes to the article until December 27th, when it was finally submitted. It is still under review until now. I hope it will be accepted, as it has consumed a lot of energy.
2023-01-03

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