Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells
Authors
Keywords
-
Journal
Genes
Volume 7, Issue 10, Pages 83
Publisher
MDPI AG
Online
2016-10-03
DOI
10.3390/genes7100083
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays
- (2016) Yunlong Wu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The novel EZH2 inhibitor, GSK126, suppresses cell migration and angiogenesis via down-regulating VEGF-A
- (2016) Ya-Tian Chen et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non-small-cell lung cancer cells
- (2016) Taichi Takashina et al. CANCER SCIENCE
- Mutation spectra of histone methyltransferases with canonical SET domains and EZH2-targeted therapy
- (2016) Masaru Katoh Epigenomics
- Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition
- (2016) Martijn AJ Koppens et al. Oncotarget
- EZH2 promotes colorectal cancer stem-like cell expansion by activating p21cip1-Wnt/β-catenin signaling
- (2016) Jian-Fang Chen et al. Oncotarget
- Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer
- (2016) Xuejiao Song et al. Scientific Reports
- MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells
- (2016) Ziqiang Zhu et al. PLoS One
- S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells
- (2015) Tsang-Pai Liu et al. ANTI-CANCER DRUGS
- Cancer statistics, 2015
- (2015) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients
- (2015) SHINICHIRO HASEGAWA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- EZH2 mediates ATO-induced apoptosis in acute myeloid leukemia cell lines through the Wnt signaling pathway
- (2015) Hao Zhang et al. TUMOR BIOLOGY
- miR-340 suppresses glioblastoma multiforme
- (2015) Daquan Huang et al. Oncotarget
- Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner
- (2015) Kailiang Zhang et al. Oncotarget
- Cancer treatment and survivorship statistics, 2014
- (2014) Carol E. DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Inhibition of EZH2 expression is associated with the proliferation, apoptosis, and migration of SW620 colorectal cancer cells in vitro
- (2014) Song-Bing He et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Selective Inhibition of EZH2 by EPZ-6438 Leads to Potent Antitumor Activity in EZH2-Mutant Non-Hodgkin Lymphoma
- (2014) S. K. Knutson et al. MOLECULAR CANCER THERAPEUTICS
- Ambra1 Is an Essential Regulator of Autophagy and Apoptosis in SW620 Cells: Pro-Survival Role of Ambra1
- (2014) Wen Gu et al. PLoS One
- 3-Deazaneplanocin A (DZNep), an Inhibitor of the Histone Methyltransferase EZH2, Induces Apoptosis and Reduces Cell Migration in Chondrosarcoma Cells
- (2014) Nicolas Girard et al. PLoS One
- Enhancer of Zeste Homolog 2 (EZH2) Promotes Progression of Cholangiocarcinoma Cells by Regulating Cell Cycle and Apoptosis
- (2013) Shigeki Nakagawa et al. ANNALS OF SURGICAL ONCOLOGY
- Autophagy-Mediated Tumor Promotion
- (2013) Jessie Yanxiang Guo et al. CELL
- The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
- (2013) Jens Füllgrabe et al. NATURE
- Clinical and Prognostic Features of Rectal Neuroendocrine Tumors
- (2013) Brett Weinstock et al. NEUROENDOCRINOLOGY
- Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
- (2013) S. K. Knutson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis
- (2012) L. Ouyang et al. CELL PROLIFERATION
- A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia
- (2012) C. Simon et al. GENES & DEVELOPMENT
- Cell death pathology: Cross-talk with autophagy and its clinical implications
- (2011) Ivano Amelio et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
- (2011) Eugenia Morselli et al. JOURNAL OF CELL BIOLOGY
- EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin
- (2011) Z-T Tong et al. ONCOGENE
- Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
- (2010) E Wirawan et al. Cell Death & Disease
- JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
- (2008) Yongjie Wei et al. MOLECULAR CELL
- Roles of the EZH2 histone methyltransferase in cancer epigenetics
- (2008) Jeffrey A. Simon et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started