Methylation Silencing of ULK2, an Autophagy Gene, Is Essential for Astrocyte Transformation and Tumor Growth

A microarray-based DNA methylation study of glioblastoma multiforme

(2014) Ramon Martinez et al.   Epigenetics

Analysis of a lung defect in autophagy-deficient mouse strains

(2013) Heesun Cheong et al.   Autophagy

A DNA Methylation Prognostic Signature of Glioblastoma: Identification of NPTX2-PTEN-NF- B Nexus

(2013) S. Shukla et al.   CANCER RESEARCH

FIP200 is required for maintenance and differentiation of postnatal neural stem cells

(2013) Chenran Wang et al.   NATURE NEUROSCIENCE

Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia

(2013) J M Devaney et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Rapamycin inhibits the growth of glioblastoma

(2012) Antonietta Arcella et al.   BRAIN RESEARCH

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

CpG Island Methylator Phenotype-Positive Tumors in the Absence of MLH1 Methylation Constitute a Distinct Subset of Duodenal Adenocarcinomas and Are Associated with Poor Prognosis

(2012) T. Fu et al.   CLINICAL CANCER RESEARCH

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

(2012) Sevin Turcan et al.   NATURE

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

(2012) Q. McAfee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

ULK1 inhibits the kinase activity of mTORC1 and cell proliferation

(2011) Chang Hwa Jung et al.   Autophagy

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy

(2011) Eun-Ju Lee et al.   Autophagy

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention

(2011) Niroop Kaza et al.   BRAIN PATHOLOGY

The multiple roles of autophagy in cancer

(2011) M. T. Rosenfeldt et al.   CARCINOGENESIS

Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

(2011) W Gao et al.   CELL DEATH AND DIFFERENTIATION

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

(2011) H. Wei et al.   GENES & DEVELOPMENT

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Identification and functional analysis of genes which confer resistance to cisplatin in tumor cells

(2010) Zchong-Zcho Wu et al.   BIOCHEMICAL PHARMACOLOGY

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

Identification of Potential Serum Biomarkers of Glioblastoma: Serum Osteopontin Levels Correlate with Poor Prognosis

(2010) P. Sreekanthreddy et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy genes as tumor suppressors

(2009) Chengyu Liang et al.   CURRENT OPINION IN CELL BIOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Epigenetic mechanisms in glioblastoma multiforme

(2009) Raman P. Nagarajan et al.   SEMINARS IN CANCER BIOLOGY

Novel Glioblastoma Markers with Diagnostic and Prognostic Value Identified through Transcriptome Analysis

(2008) S. P. Reddy et al.   CLINICAL CANCER RESEARCH

Demethylating agents in myeloid malignancies

(2008) Guillermo Garcia-Manero   CURRENT OPINION IN ONCOLOGY

Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability

(2008) Min Sung Kim et al.   HUMAN PATHOLOGY

Frameshift mutations of autophagy-related genesATG2B, ATG5, ATG9BandATG12in gastric and colorectal cancers with microsatellite instability

(2008) Mi Ran Kang et al.   JOURNAL OF PATHOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE