Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas

(2016) Roberto Würth et al.   MOLECULAR NEUROBIOLOGY

Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells

(2016) Alessandro Corsaro et al.   Oncotarget

Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

(2015) Ksenya Shchors et al.   CANCER CELL

The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma

(2015) Barbara Banelli et al.   CELL CYCLE

Autophagy, Metabolism, and Cancer

(2015) E. White et al.   CLINICAL CANCER RESEARCH

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

HDAC Inhibitors as Novel Anti-Cancer Therapeutics

(2015) Cristabelle Souza et al.   Recent Patents on Anti-Cancer Drug Discovery

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current

(2015) Marta Gritti et al.   Oncotarget

To be or not to be, the level of autophagy is the question: Dual roles of autophagy in the survival response to starvation

(2014) Chanhee Kang et al.   Autophagy

Histone deacetylase inhibitors and cell death

(2014) Jing Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy Is Modulated in Human Neuroblastoma Cells Through Direct Exposition to Low Frequency Electromagnetic Fields

(2014) Nicoletta Marchesi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

(2014) Donatella Del Bufalo et al.   Molecular Cancer

Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells

(2014) Valentina Villa et al.   MOLECULAR NEUROBIOLOGY

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Inhibition of autophagy significantly enhances combination therapy with sorafenib and HDAC inhibitors for human hepatoma cells

(2014) Hang Yuan   WORLD JOURNAL OF GASTROENTEROLOGY

New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells

(2014) Roberto Würth et al.   Biomed Research International

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures

(2013) Elisa Carra et al.   CELL CYCLE

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy in tumour cell death

(2013) Robin L. Macintosh et al.   SEMINARS IN CANCER BIOLOGY

Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity

(2013) Monica Gatti et al.   TOXICOLOGY

HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses

(2013) J E Bolden et al.   Cell Death & Disease

Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression

(2012) E. Pazolli et al.   CANCER RESEARCH

Autophagy is required for the activation of NFκB

(2012) Alfredo Criollo et al.   CELL CYCLE

Metformin selectively affects human glioblastoma tumor-initiating cell viability

(2012) Roberto Würth et al.   CELL CYCLE

The Definition of Primary and Secondary Glioblastoma

(2012) H. Ohgaki et al.   CLINICAL CANCER RESEARCH

The status of the art of human malignant glioma management: the promising role of targeting tumor-initiating cells

(2012) Tullio Florio et al.   DRUG DISCOVERY TODAY

AUTOCOUNTER, an ImageJ JavaScript to analyze LC3B-GFP expression dynamics in autophagy-induced astrocytoma cells

(2012) L. Fassina et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Autophagy and ionizing radiation in tumors: The “survive or not survive” dilemma

(2012) Silvia Palumbo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Combination of Pan-Histone Deacetylase Inhibitor and Autophagy Inhibitor Exerts Superior Efficacy against Triple-Negative Human Breast Cancer Cells

(2012) R. Rao et al.   MOLECULAR CANCER THERAPEUTICS

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

(2011) Shinji Saiki et al.   Autophagy

Heterogeneity Maintenance in Glioblastoma: A Social Network

(2011) R. Bonavia et al.   CANCER RESEARCH

Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer

(2011) K Ted Thurn et al.   Future Oncology

HDACs link the DNA damage response, processing of double-strand breaks and autophagy

(2011) Thomas Robert et al.   NATURE

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Gefitinib Targets EGFR Dimerization and ERK1/2 Phosphorylation to Inhibit Pleural Mesothelioma Cell Proliferation

(2010) R. E. Favoni et al.   CURRENT CANCER DRUG TARGETS

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Different Response of Human Glioma Tumor-initiating Cells to Epidermal Growth Factor Receptor Kinase Inhibitors

(2009) Fabrizio Griffero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells

(2008) Akio Soeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY