Assessing the Role of Lipids in the Molecular Mechanism of Membrane Proteins
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Assessing the Role of Lipids in the Molecular Mechanism of Membrane Proteins
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 14, Pages 7267
Publisher
MDPI AG
Online
2021-07-06
DOI
10.3390/ijms22147267
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Visualization of the mechanosensitive ion channel MscS under membrane tension
- (2021) Yixiao Zhang et al. NATURE
- Cryo-EM structure of an activated GPCR–G protein complex in lipid nanodiscs
- (2021) Meng Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Detergent-free Lipodisq Nanoparticles Facilitate High-Resolution Mass Spectrometry of Folded Integral Membrane Proteins
- (2021) Kin Kuan Hoi et al. NANO LETTERS
- Structural insights into the lipid and ligand regulation of serotonin receptors
- (2021) Peiyu Xu et al. NATURE
- More Than Just Closed and Open: Unraveling a Mechanosensor
- (2021) Vanessa J. Flegler et al. TRENDS IN BIOCHEMICAL SCIENCES
- Phospholipid translocation captured in a bifunctional membrane protein MprF
- (2021) Danfeng Song et al. Nature Communications
- The Protein Imager: a full-featured online molecular viewer interface with server-side HQ-rendering capabilities
- (2020) Gianluca Tomasello et al. BIOINFORMATICS
- Structure of the M2 muscarinic receptor–β-arrestin complex in a lipid nanodisc
- (2020) Dean P. Staus et al. NATURE
- Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter
- (2020) Kevin L. Jagessar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer
- (2020) Pramod Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins
- (2020) Gabriella Angiulli et al. eLife
- A glimpse into the molecular mechanism of integral membrane proteins through hydrogen–deuterium exchange mass spectrometry
- (2020) Chloe Martens et al. PROTEIN SCIENCE
- Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
- (2020) Meghna Sobti et al. Nature Communications
- Membrane Chemistry Tunes the Structure of a Peptide Transporter
- (2020) Tanya Lasitza-Male et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism
- (2020) Hiroto Shimada et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Gating of human TRPV3 in a lipid bilayer
- (2020) Zengqin Deng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+channels in nanodisc
- (2020) Shuai Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM analysis of a membrane protein embedded in the liposome
- (2020) Xia Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modular microfluidics enables kinetic insight from time-resolved cryo-EM
- (2020) Märt-Erik Mäeots et al. Nature Communications
- Structural basis for the modulation of pentameric ligand-gated ion channel function by lipids
- (2020) Mackenzie J. Thompson et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The Multidrug Transporter MdfA Deviates from the Canonical Model of Alternating Access of MFS Transporters
- (2020) Eliane H. Yardeni et al. JOURNAL OF MOLECULAR BIOLOGY
- Shared structural mechanisms of general anaesthetics and benzodiazepines
- (2020) Jeong Joo Kim et al. NATURE
- Selective regulation of human TRAAK channels by biologically active phospholipids
- (2020) Samantha Schrecke et al. Nature Chemical Biology
- Nanodiscs and mass spectrometry: Making membranes fly
- (2020) Michael T. Marty INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
- Fake It ‘Till You Make It—The Pursuit of Suitable Membrane Mimetics for Membrane Protein Biophysics
- (2020) Johannes Thoma et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Functional Oligomeric Forms of Uncoupling Protein 2: Strong Evidence for Asymmetry in Protein and Lipid Bilayer Systems
- (2020) Afshan Ardalan et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Current Methods for Detecting Cell Membrane Transient Interactions
- (2020) Yousef Bagheri et al. Frontiers in Chemistry
- A 10-year meta-analysis of membrane protein structural biology: Detergents, membrane mimetics, and structure determination techniques
- (2020) Brendon C. Choy et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel
- (2019) Yang Liu et al. Nature Communications
- Emerging Diversity in Lipid–Protein Interactions
- (2019) Valentina Corradi et al. CHEMICAL REVIEWS
- Late steps in bacterial translation initiation visualized using time-resolved cryo-EM
- (2019) Sandip Kaledhonkar et al. NATURE
- MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine
- (2019) Chih-Chia Su et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural insight into TRPV5 channel function and modulation
- (2019) Shangyu Dang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors
- (2019) Reza Dastvan et al. SCIENCE
- Structural basis for functional interactions in dimers of SLC26 transporters
- (2019) Yung-Ning Chang et al. Nature Communications
- Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs
- (2019) David M Kern et al. eLife
- Regulatory switch at the cytoplasmic interface controls TRPV channel gating
- (2019) Lejla Zubcevic et al. eLife
- From polymer chemistry to structural biology: The development of SMA and related amphipathic polymers for membrane protein extraction and solubilisation
- (2019) Juan Francisco Bada Juarez et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Structure of the Mechanosensitive Channel MscS Embedded in the Membrane Bilayer
- (2019) Tim Rasmussen et al. JOURNAL OF MOLECULAR BIOLOGY
- Conformation space of a heterodimeric ABC exporter under turnover conditions
- (2019) Susanne Hofmann et al. NATURE
- Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase
- (2019) Soo Y. Ro et al. Nature Communications
- Cryo-EM Studies of TMEM16F Calcium-Activated Ion Channel Suggest Features Important for Lipid Scrambling
- (2019) Shengjie Feng et al. Cell Reports
- Molecular mechanism of TRPV2 channel modulation by cannabidiol
- (2019) Ruth A Pumroy et al. eLife
- Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging
- (2019) Florian KM Schur CURRENT OPINION IN STRUCTURAL BIOLOGY
- Specific Residues in a Purine Transporter Are Critical for Dimerization, ER Exit, and Function
- (2019) Anezia Kourkoulou et al. GENETICS
- Integrating hydrogen–deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins
- (2019) Chloe Martens et al. Nature Protocols
- Structural basis of temperature sensation by the TRP channel TRPV3
- (2019) Appu K. Singh et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii
- (2019) Luke L. McGoldrick et al. Nature Communications
- Structure-based characterization of novel TRPV5 inhibitors
- (2019) Taylor ET Hughes et al. eLife
- Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS
- (2019) Bharat Reddy et al. eLife
- Structure and Dynamics of Membrane Proteins from Solid-State NMR
- (2018) Venkata S. Mandala et al. Annual Review of Biophysics
- Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale
- (2018) Mavis Jiarong Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of the alternative complex III in a supercomplex with cytochrome oxidase
- (2018) Chang Sun et al. NATURE
- Single-molecule probing of the conformational homogeneity of the ABC transporter BtuCD
- (2018) Min Yang et al. Nature Chemical Biology
- Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ
- (2018) Jani Reddy Bolla et al. Nature Chemistry
- Identifying key membrane protein lipid interactions using mass spectrometry
- (2018) Kallol Gupta et al. Nature Protocols
- Orthosteric and allosteric action of the C5a receptor antagonists
- (2018) Heng Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Lipid binding attenuates channel closure of the outer membrane protein OmpF
- (2018) Idlir Liko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Allostery revealed within lipid binding events to membrane proteins
- (2018) John W. Patrick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer
- (2018) Eitan Lerner et al. SCIENCE
- Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research
- (2018) Ali Flayhan et al. STRUCTURE
- Orthosteric and allosteric action of the C5a receptor antagonists
- (2018) Heng Liu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT
- (2018) Patrick S. Merkle et al. Science Advances
- Structural and functional characterization of protein–lipid interactions of the Salmonella typhimurium melibiose transporter MelB
- (2018) Parameswaran Hariharan et al. BMC BIOLOGY
- Conformational dynamics of the ABC transporter McjD seen by single‐molecule FRET
- (2018) Florence Husada et al. EMBO JOURNAL
- PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
- (2018) Hsin-Yung Yen et al. NATURE
- Structural basis for activation of voltage sensor domains in an ion channel TPC1
- (2018) Alexander F. Kintzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Visualizing and discovering cellular structures with super-resolution microscopy
- (2018) Yaron M. Sigal et al. SCIENCE
- Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs
- (2018) Doreen Matthies et al. eLife
- The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution
- (2018) Michael Luke Carlson et al. eLife
- Chemical Additives Enable Native Mass Spectrometry Measurement of Membrane Protein Oligomeric State within Intact Nanodiscs
- (2018) James E. Keener et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure and activity of lipid bilayer within a membrane-protein transporter
- (2018) Weihua Qiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry
- (2018) Dror S. Chorev et al. SCIENCE
- Direct protein-lipid interactions shape the conformational landscape of secondary transporters
- (2018) Chloe Martens et al. Nature Communications
- Conformational ensemble of the human TRPV3 ion channel
- (2018) Lejla Zubcevic et al. Nature Communications
- Cryo-EM structure of the mechanically activated ion channel OSCA1.2
- (2018) Sebastian Jojoa-Cruz et al. eLife
- Structure of the human multidrug transporter ABCG2
- (2017) Nicholas M. I. Taylor et al. NATURE
- Structure of mammalian endolysosomal TRPML1 channel in nanodiscs
- (2017) Qingfeng Chen et al. NATURE
- Opening of the human epithelial calcium channel TRPV6
- (2017) Luke L. McGoldrick et al. NATURE
- The role of interfacial lipids in stabilizing membrane protein oligomers
- (2017) Kallol Gupta et al. NATURE
- Conformational dynamics of a neurotransmitter:sodium symporter in a lipid bilayer
- (2017) Suraj Adhikary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Specific phospholipid binding to Na,K-ATPase at two distinct sites
- (2017) Michael Habeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the human TRPM4 ion channel in a lipid nanodisc
- (2017) Henriette E. Autzen et al. SCIENCE
- Allosteric modulation of protein-protein interactions by individual lipid binding events
- (2017) Xiao Cong et al. Nature Communications
- Membrane cholesterol access into a G-protein-coupled receptor
- (2017) Ramon Guixà-González et al. Nature Communications
- Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters
- (2017) Michael Landreh et al. Nature Communications
- Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter
- (2017) Andreas Anderluh et al. Nature Communications
- The folding, stability and function of lactose permease differ in their dependence on bilayer lipid composition
- (2017) Heather E. Findlay et al. Scientific Reports
- The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
- (2016) Peter S. Shen et al. CELL
- Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD
- (2016) Shahid Mehmood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
- (2016) Yuan Gao et al. NATURE
- High-resolution mass spectrometry of small molecules bound to membrane proteins
- (2016) Joseph Gault et al. NATURE METHODS
- A comprehensive map of molecular drug targets
- (2016) Rita Santos et al. NATURE REVIEWS DRUG DISCOVERY
- Lipids modulate the conformational dynamics of a secondary multidrug transporter
- (2016) Chloé Martens et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Dimer interface of bovine cytochromecoxidase is influenced by local posttranslational modifications and lipid binding
- (2016) Idlir Liko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipids modulate the conformational dynamics of a secondary multidrug transporter
- (2016) Chloé Martens et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles
- (2015) Michael T. Marty et al. ANALYTICAL CHEMISTRY
- A review of traditional and emerging methods to characterize lipid–protein interactions in biological membranes
- (2015) Chih-Yun Hsia et al. Analytical Methods
- General and specific lipid–protein interactions in Na,K-ATPase
- (2015) F. Cornelius et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The Effect of Detergent, Temperature, and Lipid on the Oligomeric State of MscL Constructs: Insights from Mass Spectrometry
- (2015) Eamonn Reading et al. CHEMISTRY & BIOLOGY
- Allosteric regulation of G protein–coupled receptor activity by phospholipids
- (2015) Rosie Dawaliby et al. Nature Chemical Biology
- A subset of annular lipids is linked to the flippase activity of an ABC transporter
- (2015) Chérine Bechara et al. Nature Chemistry
- The systematic analysis of protein–lipid interactions comes of age
- (2015) Antoine-Emmanuel Saliba et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Principles of cryo-EM single-particle image processing
- (2015) Fred J. Sigworth Microscopy
- Cholesterol Modulates the Dimer Interface of the β2-Adrenergic Receptor via Cholesterol Occupancy Sites
- (2014) Xavier Prasanna et al. BIOPHYSICAL JOURNAL
- Single Molecule Analysis Reveals Coexistence of Stable Serotonin Transporter Monomers and Oligomers in the Live Cell Plasma Membrane
- (2014) Andreas Anderluh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intrinsic Conformational Plasticity of Native EmrE Provides a Pathway for Multidrug Resistance
- (2014) Min-Kyu Cho et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Membrane proteins bind lipids selectively to modulate their structure and function
- (2014) Arthur Laganowsky et al. NATURE
- TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2
- (2014) Nobuaki Takahashi et al. Nature Communications
- Perspectives in Enzymology of Membrane Proteins by Solid-State NMR
- (2013) Sandra J. Ullrich et al. ACCOUNTS OF CHEMICAL RESEARCH
- Structural evidence for functional lipid interactions in the betaine transporter BetP
- (2013) Caroline Koshy et al. EMBO JOURNAL
- How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters
- (2013) Aravind Penmatsa et al. JOURNAL OF PHYSIOLOGY-LONDON
- Protonation drives the conformational switch in the multidrug transporter LmrP
- (2013) Matthieu Masureel et al. Nature Chemical Biology
- Importance of lipid-pore loop interface for potassium channel structure and function
- (2013) E. A. W. van der Cruijsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate
- (2013) F. Buchmayer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump
- (2013) J. Marcoux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DEER Distance Measurements on Proteins
- (2012) Gunnar Jeschke Annual Review of Physical Chemistry
- Dynamics of a bacterial multidrug ABC transporter in the inward- and outward-facing conformations
- (2012) S. Mehmood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward the Fourth Dimension of Membrane Protein Structure: Insight into Dynamics from Spin-Labeling EPR Spectroscopy
- (2011) Hassane S. Mchaourab et al. STRUCTURE
- Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry
- (2010) Christine M. Hebling et al. ANALYTICAL CHEMISTRY
- Hydrogen exchange mass spectrometry for studying protein structure and dynamics
- (2010) Lars Konermann et al. CHEMICAL SOCIETY REVIEWS
- Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS
- (2009) John R. Engen ANALYTICAL CHEMISTRY
- Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
- (2009) Markus Almén et al. BMC BIOLOGY
- Membrane protein assembly into Nanodiscs
- (2009) Timothy H. Bayburt et al. FEBS LETTERS
- Crystal structure of the sodium–potassium pump at 2.4 Å resolution
- (2009) Takehiro Shinoda et al. NATURE
- Protein modulation of lipids, and vice-versa, in membranes
- (2008) Derek Marsh BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?
- (2008) Yamuna Devi Paila et al. GLYCOCONJUGATE JOURNAL
- X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
- (2008) Nicolas Bocquet et al. NATURE
- A practical guide to single-molecule FRET
- (2008) Rahul Roy et al. NATURE METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation