Single-molecule probing of the conformational homogeneity of the ABC transporter BtuCD

ATP binding and hydrolysis disrupt the high-affinity interaction between the heme ABC transporter HmuUV and its cognate substrate-binding protein

(2017) Hiba Qasem-Abdullah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-molecule analysis of ligand efficacy in β2AR–G-protein activation

(2017) G. Glenn Gregorio et al.   NATURE

Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

(2017) Brandy Verhalen et al.   NATURE

L-glutamine Induces Expression of Listeria monocytogenes Virulence Genes

(2017) Adi Haber et al.   PLoS Pathogens

Exploring conformational equilibria of a heterodimeric ABC transporter

(2017) M Hadi Timachi et al.   eLife

An updated structural classification of substrate-binding proteins

(2016) Giel H. Scheepers et al.   FEBS LETTERS

Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

(2016) Manuel F Juette et al.   NATURE METHODS

Mechanistic diversity in ATP-binding cassette (ABC) transporters

(2016) Kaspar P Locher   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of bacterial haem importer complex in the inward-facing conformation

(2016) Youichi Naoe et al.   Nature Communications

Mechanistic diversity in ATP-binding cassette (ABC) transporters

(2016) Kaspar P Locher   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The uncoupled ATPase activity of the ABC transporter BtuC2D2 leads to a hysteretic conformational change, conformational memory and improved activity

(2016) Nurit Livnat-Levanon et al.   Scientific Reports

Metal binding spectrum and model structure of the Bacillus anthracis virulence determinant MntA

(2015) Elena Vigonsky et al.   Metallomics

Transport domain unlocking sets the uptake rate of an aspartate transporter

(2015) Nurunisa Akyuz et al.   NATURE

Structure and mechanism of an active lipid-linked oligosaccharide flippase

(2015) Camilo Perez et al.   NATURE

Conformational dynamics in substrate-binding domains influences transport in the ABC importer GlnPQ

(2014) Giorgos Gouridis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of AMP-PNP–bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD–F

(2014) Vladimir M Korkhov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

(2014) Smriti Mishra et al.   eLife

Conformational Cycle of the Vitamin B12ABC Importer in Liposomes Detected by Double Electron-Electron Resonance (DEER)

(2013) Benesh Joseph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transport dynamics in a glutamate transporter homologue

(2013) Nurunisa Akyuz et al.   NATURE

Structural and mechanistic insights into prokaryotic energy-coupling factor transporters

(2013) Dirk J. Slotboom   NATURE REVIEWS MICROBIOLOGY

A single intact ATPase site of the ABC transporter BtuCD drives 5% transport activity yet supports full in vivo vitamin B12 utilization

(2013) N. Tal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two molybdate/tungstate ABC transporters that interact very differently with their substrate binding proteins

(2013) E. Vigonsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of AMP-PNP-bound vitamin B12 transporter BtuCD–F

(2012) Vladimir M. Korkhov et al.   NATURE

X-ray structure of the Yersinia pestis heme transporter HmuUV

(2012) Jae-Sung Woo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Receptor–transporter interactions of canonical ATP-binding cassette import systems in prokaryotes

(2011) Erwin Schneider et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Transmembrane Gate Movements in the Type II ATP-binding Cassette (ABC) Importer BtuCD-F during Nucleotide Cycle

(2011) Benesh Joseph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial ATP-driven transporters of transition metals: physiological roles, mechanisms of action, and roles in bacterial virulence

(2011) Joshua S. Klein et al.   Metallomics

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

Single-molecule dynamics of gating in a neurotransmitter transporter homologue

(2010) Yongfang Zhao et al.   NATURE

ABC proteins in antigen translocation and viral inhibition

(2010) David Parcej et al.   Nature Chemical Biology

A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex formation

(2010) Oded Lewinson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternating Access in Maltose Transporter Mediated by Rigid-Body Rotations

(2009) Dheeraj Khare et al.   MOLECULAR CELL

ABC transporters: the power to change

(2009) Douglas C. Rees et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural insights into ABC transporter mechanism

(2008) Michael L Oldham et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems

(2008) A. L. Davidson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS