The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism

Regulatory switch at the cytoplasmic interface controls TRPV channel gating

(2019) Lejla Zubcevic et al.   eLife

Inhibition of the Warm-temperature Activated Ca2+-permeable TRPV3 Channel Attenuates Atopic Dermatitis

(2019) Yaxuan Qu et al.   MOLECULAR PHARMACOLOGY

The ion selectivity filter is not an activation gate in TRPV1-3 channels

(2019) Andrés Jara-Oseguera et al.   eLife

Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms

(2018) Zengqin Deng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms

(2018) Zengqin Deng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Structure and gating mechanism of the transient receptor potential channel TRPV3

(2018) Appu K. Singh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational ensemble of the human TRPV3 ion channel

(2018) Lejla Zubcevic et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis

(2018) Jasenko Zivanov et al.   IUCrJ

Structure of mammalian endolysosomal TRPML1 channel in nanodiscs

(2017) Qingfeng Chen et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Single-residue molecular switch for high-temperature dependence of vanilloid receptor TRPV3

(2017) Beiying Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

(2016) Yuan Gao et al.   NATURE

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Cholesterol sensitises the transient receptor potential channel TRPV3 to lower temperatures and activator concentrations

(2013) Anke S. Klein et al.   CELL CALCIUM

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel

(2013) Lin Tang et al.   NATURE

Exome Sequencing Reveals Mutations in TRPV3 as a Cause of Olmsted Syndrome

(2012) Zhimiao Lin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Heteromeric Heat-sensitive Transient Receptor Potential Channels Exhibit Distinct Temperature and Chemical Response

(2011) Wei Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P2hydrolysis

(2011) Julia F. Doerner et al.   JOURNAL OF GENERAL PHYSIOLOGY

Hysteresis of gating underlines sensitization of TRPV3 channels

(2011) Beiying Liu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers

(2010) Y. V. Grinkova et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

Pore region of TRPV3 ion channel is specifically required for heat activation

(2008) Jörg Grandl et al.   NATURE NEUROSCIENCE

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies

(2008) Abhiram Dukkipati et al.   PROTEIN EXPRESSION AND PURIFICATION

Monoterpenoid agonists of TRPV3

(2007) A K Vogt-Eisele et al.   BRITISH JOURNAL OF PHARMACOLOGY