Structural basis of temperature sensation by the TRP channel TRPV3

Cytoplasmic Inter-Subunit Interface Controls Use-Dependence of Thermal Activation of TRPV3 Channel

(2019) Lucie Macikova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure and gating mechanism of the transient receptor potential channel TRPV3

(2018) Appu K. Singh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine

(2018) Marina A. Kasimova et al.   JOURNAL OF GENERAL PHYSIOLOGY

Conformational ensemble of the human TRPV3 ion channel

(2018) Lejla Zubcevic et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Single-residue molecular switch for high-temperature dependence of vanilloid receptor TRPV3

(2017) Beiying Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels

(2016) Ignacio Diaz-Franulic et al.   Annual Review of Biophysics

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel function

(2013) Di-Jing Shi et al.   Protein & Cell

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Hysteresis of gating underlines sensitization of TRPV3 channels

(2011) Beiying Liu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels

(2011) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

(2010) Jörg Grandl et al.   NATURE NEUROSCIENCE

Pore region of TRPV3 ion channel is specifically required for heat activation

(2008) Jörg Grandl et al.   NATURE NEUROSCIENCE