Opening of the human epithelial calcium channel TRPV6

Channel opening and gating mechanism in AMPA-subtype glutamate receptors

(2017) Edward C. Twomey et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

A Gate Hinge Controls the Epithelial Calcium Channel TRPV5

(2017) Jenny van der Wijst et al.   Scientific Reports

Swapping of transmembrane domains in the epithelial calcium channel TRPV6

(2017) Appu K. Singh et al.   Scientific Reports

The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs

(2016) Peter S. Shen et al.   CELL

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

(2016) Yuan Gao et al.   NATURE

Crystal structure of the epithelial calcium channel TRPV6

(2016) Kei Saotome et al.   NATURE

Covalently circularized nanodiscs for studying membrane proteins and viral entry

(2016) Mahmoud L Nasr et al.   NATURE METHODS

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the full-length TRPV2 channel by cryo-EM

(2016) Kevin W. Huynh et al.   Nature Communications

Cryo-electron microscopy structure of the TRPV2 ion channel

(2016) Lejla Zubcevic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels

(2016) Phanindra Velisetty et al.   Scientific Reports

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the TRPA1 ion channel suggests regulatory mechanisms

(2015) Candice E. Paulsen et al.   NATURE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

Thein VivoTRPV6 Protein Starts at a Non-AUG Triplet, Decoded as Methionine, Upstream of Canonical Initiation at AUG

(2013) Claudia Fecher-Trost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption

(2012) Titia E. Woudenberg-Vrenken et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB)

(2012) Gergely Kovacs et al.   CELL CALCIUM

The role of the TRPV6 channel in cancer

(2012) V’yacheslav Lehen’kyi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5)P2

(2011) Eleonora Zakharian et al.   FASEB JOURNAL

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels

(2010) Stepana Boukalova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY