The systematic analysis of protein–lipid interactions comes of age

Phosphatidylinositol transfer proteins and instructive regulation of lipid kinase biology

(2015) Aby Grabon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

(2015) Marielle S. Köberlin et al.   CELL

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

(2015) Micah J. Niphakis et al.   CELL

Bifunctional Fatty Acid Chemical Reporter for Analyzing S-Palmitoylated Membrane Protein–Protein Interactions in Mammalian Cells

(2015) Tao Peng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

HIV gp41–mediated membrane fusion occurs at edges of cholesterol-rich lipid domains

(2015) Sung-Tae Yang et al.   Nature Chemical Biology

A subset of annular lipids is linked to the flippase activity of an ABC transporter

(2015) Chérine Bechara et al.   Nature Chemistry

Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates

(2015) Varnavas D. Mouchlis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains

(2015) Ivana Vonkova et al.   Cell Reports

High-Throughput Proteomics

(2014) Zhaorui Zhang et al.   Annual Review of Analytical Chemistry

Caged lipids as tools for investigating cellular signaling

(2014) Doris Höglinger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fat & fabulous: Bifunctional lipids in the spotlight

(2014) Per Haberkant et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Membrane proteins bind lipids selectively to modulate their structure and function

(2014) Arthur Laganowsky et al.   NATURE

Lipid landscapes and pipelines in membrane homeostasis

(2014) Joost C.M. Holthuis et al.   NATURE

Amphotericin forms an extramembranous and fungicidal sterol sponge

(2014) Thomas M Anderson et al.   Nature Chemical Biology

Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering

(2014) Lu Wei et al.   NATURE METHODS

Measuring genetic interactions in human cells by RNAi and imaging

(2014) Christina Laufer et al.   Nature Protocols

Phospholipid - Driven gene regulation

(2013) Paul M. Musille et al.   FEBS LETTERS

ActivatingAKT2Mutation: Hypoinsulinemic Hypoketotic Hypoglycemia

(2013) Ved Bhushan Arya et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Lipid Directed Intrinsic Membrane Protein Segregation

(2013) Jesper S. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Lipid E-MAP Identifies Ubx2 as a Critical Regulator of Lipid Saturation and Lipid Bilayer Stress

(2013) Michal A. Surma et al.   MOLECULAR CELL

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

A quantitative liposome microarray to systematically characterize protein-lipid interactions

(2013) Antoine-Emmanuel Saliba et al.   NATURE METHODS

Detergent-free mass spectrometry of membrane protein complexes

(2013) Jonathan T S Hopper et al.   NATURE METHODS

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

(2013) Jonathan J Hulce et al.   NATURE METHODS

Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides

(2013) Dor Salomon et al.   Nature Communications

Profiling Lipid–protein Interactions Using Nonquenched Fluorescent Liposomal Nanovesicles and Proteome Microarrays

(2012) Kuan-Yi Lu et al.   MOLECULAR & CELLULAR PROTEOMICS

A simple guide to biochemical approaches for analyzing protein–lipid interactions

(2012) Hongxia Zhao et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae

(2012) Mohan Babu et al.   NATURE

Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

(2012) F.-Xabier Contreras et al.   NATURE

The role of lipids in defining membrane protein interactions: insights from mass spectrometry

(2012) Nelson P. Barrera et al.   TRENDS IN CELL BIOLOGY

Host targeting of virulence determinants and phosphoinositides in blood stage malaria parasites

(2012) Souvik Bhattacharjee et al.   TRENDS IN PARASITOLOGY

Mechanisms of Membrane Curvature Sensing

(2011) Bruno Antonny   Annual Review of Biochemistry

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Crystal Structure and Allosteric Activation of Protein Kinase C βII

(2011) Thomas A. Leonard et al.   CELL

Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium

(2011) Matthew R. Whorton et al.   CELL

Label-free imaging of lipid dynamics using Coherent Anti-stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) microscopy

(2011) Andrew Folick et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Membrane protein sequestering by ionic protein–lipid interactions

(2011) Geert van den Bogaart et al.   NATURE

A Mosaic Activating Mutation inAKT1Associated with the Proteus Syndrome

(2011) Marjorie J. Lindhurst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination

(2011) H. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mass Spectrometry of Intact V-Type ATPases Reveals Bound Lipids and the Effects of Nucleotide Binding

(2011) M. Zhou et al.   SCIENCE

Conditional Peripheral Membrane Proteins: Facing up to Limited Specificity

(2011) Katarina Moravcevic et al.   STRUCTURE

Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids

(2010) Katarina Moravcevic et al.   CELL

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

A Comprehensive Comparison of Transmembrane Domains Reveals Organelle-Specific Properties

(2010) Hayley J. Sharpe et al.   CELL

Extensive In Vivo Metabolite-Protein Interactions Revealed by Large-Scale Systematic Analyses

(2010) Xiyan Li et al.   CELL

Giant Vesicles: Preparations and Applications

(2010) Peter Walde et al.   CHEMBIOCHEM

Revealing a signaling role of phytosphingosine-1-phosphate in yeast

(2010) L Ashley Cowart et al.   Molecular Systems Biology

A systematic screen for protein–lipid interactions in Saccharomyces cerevisiae

(2010) Oriol Gallego et al.   Molecular Systems Biology

Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

(2010) Devaraj Subramanian et al.   Nature Chemical Biology

Non-vesicular lipid transport by lipid-transfer proteins and beyond

(2010) Sima Lev   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanisms in signal transduction at the membrane

(2010) Jay T Groves et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking

(2010) Pablo S Aguilar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proteomic identification of phosphatidylinositol (3,4,5) triphosphate-binding proteins in Dictyostelium discoideum

(2010) P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosteric gating of Son of sevenless activity by the histone domain

(2010) Kamlesh K. Yadav et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains

(2010) B. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

(2009) J. D. Matute et al.   BLOOD

Photocrosslinking and Click Chemistry Enable the Specific Detection of Proteins Interacting with Phospholipids at the Membrane Interface

(2009) Jacob Gubbens et al.   CHEMISTRY & BIOLOGY

Films of Agarose Enable Rapid Formation of Giant Liposomes in Solutions of Physiologic Ionic Strength

(2009) Kim S. Horger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

(2009) Nelson P Barrera et al.   NATURE METHODS

Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart

(2009) J. D. Scott et al.   SCIENCE

Liposomes: Technologies and Analytical Applications

(2008) Aldo Jesorka et al.   Annual Review of Analytical Chemistry

Update of the LIPID MAPS comprehensive classification system for lipids

(2008) Eoin Fahy et al.   JOURNAL OF LIPID RESEARCH

Comprehensive Identification of PIP3-Regulated PH Domains from C. elegans to H. sapiens by Model Prediction and Live Imaging

(2008) Wei Sun Park et al.   MOLECULAR CELL

Membrane recognition by phospholipid-binding domains

(2008) Mark A. Lemmon   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipid signalling in disease

(2008) Matthias P. Wymann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Unilamellar vesicle formation and encapsulation by microfluidic jetting

(2008) J. C. Stachowiak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA