The role of interfacial lipids in stabilizing membrane protein oligomers

Shared Molecular Mechanisms of Membrane Transporters

(2016) David Drew et al.   Annual Review of Biochemistry

A sliding selectivity scale for lipid binding to membrane proteins

(2016) Michael Landreh et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

(2016) Yuan Gao et al.   NATURE

X-ray structures and mechanism of the human serotonin transporter

(2016) Jonathan A. Coleman et al.   NATURE

High-resolution mass spectrometry of small molecules bound to membrane proteins

(2016) Joseph Gault et al.   NATURE METHODS

Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters

(2016) Mathieu Coincon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters

(2016) Mathieu Coincon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

The Role of the Detergent Micelle in Preserving the Structure of Membrane Proteins in the Gas Phase

(2015) Eamonn Reading et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Extending native mass spectrometry approaches to integral membrane proteins

(2015) Albert Konijnenberg et al.   BIOLOGICAL CHEMISTRY

Alchembed: A Computational Method for Incorporating Multiple Proteins into Complex Lipid Geometries

(2015) Elizabeth Jefferys et al.   Journal of Chemical Theory and Computation

Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities

(2015) Juan Zhen et al.   JOURNAL OF NEUROCHEMISTRY

Structural insights into µ-opioid receptor activation

(2015) Weijiao Huang et al.   NATURE

Propagation of conformational changes during μ-opioid receptor activation

(2015) Rémy Sounier et al.   NATURE

The role of lipids in mechanosensation

(2015) Christos Pliotas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes

(2015) Phillip J. Stansfeld et al.   STRUCTURE

The role of lipids in mechanosensation

(2015) Christos Pliotas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lipidomics: Analysis of the Lipid Composition of Cells and Subcellular Organelles by Electrospray Ionization Mass Spectrometry

(2014) Britta Brügger   Annual Review of Biochemistry

Variation of the Detergent-Binding Capacity and Phospholipid Content of Membrane Proteins When Purified in Different Detergents

(2014) Hüseyin Ilgü et al.   BIOPHYSICAL JOURNAL

Single Molecule Analysis Reveals Coexistence of Stable Serotonin Transporter Monomers and Oligomers in the Live Cell Plasma Membrane

(2014) Andreas Anderluh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights

(2014) Chiara Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

Membrane proteins bind lipids selectively to modulate their structure and function

(2014) Arthur Laganowsky et al.   NATURE

Structures of bacterial homologues of SWEET transporters in two distinct conformations

(2014) Yan Xu et al.   NATURE

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

(2014) H. Wu et al.   SCIENCE

Integral Membrane Proteins and Bilayer Proteomics

(2013) Julian P. Whitelegge   ANALYTICAL CHEMISTRY

Non-covalent binding of membrane lipids to membrane proteins

(2013) Philip L. Yeagle   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Architecture and Membrane Interactions of the EGF Receptor

(2013) Anton Arkhipov et al.   CELL

A flexible algorithm for calculating pair interactions on SIMD architectures

(2013) Szilárd Páll et al.   COMPUTER PHYSICS COMMUNICATIONS

Detergent-free mass spectrometry of membrane protein complexes

(2013) Jonathan T S Hopper et al.   NATURE METHODS

Mass spectrometry of intact membrane protein complexes

(2013) Arthur Laganowsky et al.   Nature Protocols

An analysis of oligomerization interfaces in transmembrane proteins

(2013) Jose M Duarte et al.   BMC STRUCTURAL BIOLOGY

Restructuring G-Protein- Coupled Receptor Activation

(2012) Martin Audet et al.   CELL

Improved Parameters for the Martini Coarse-Grained Protein Force Field

(2012) Djurre H. de Jong et al.   Journal of Chemical Theory and Computation

Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates

(2012) B. K. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology

(2011) Jürgen Cox et al.   Annual Review of Biochemistry

MDAnalysis: A toolkit for the analysis of molecular dynamics simulations

(2011) Naveen Michaud-Agrawal et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

(2011) Scott B. Hansen et al.   NATURE

Molecular Simulation Approaches to Membrane Proteins

(2011) Phillip J. Stansfeld et al.   STRUCTURE

Ion Mobility Mass Spectrometry of Two Tetrameric Membrane Protein Complexes Reveals Compact Structures and Differences in Stability and Packing

(2010) Sheila C. Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site

(2010) Chayne L. Piscitelli et al.   NATURE

β-Sheet-dependent Dimerization Is Essential for the Stability of NhaA Na+/H+Antiporter

(2009) Katia Herz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of receptor oligomerization by FRAP microscopy

(2009) Sandra Dorsch et al.   NATURE METHODS

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

(2009) Nelson P Barrera et al.   NATURE METHODS

Assembly reflects evolution of protein complexes

(2008) Emmanuel D. Levy et al.   NATURE

Micelles Protect Membrane Complexes from Solution to Vacuum

(2008) N. P. Barrera et al.   SCIENCE

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation