Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

Conformational ensemble of the sodium-coupled aspartate transporter

(2013) Elka R Georgieva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conformational heterogeneity of the aspartate transporter GltPh

(2013) Inga Hänelt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Massign: An Assignment Strategy for Maximizing Information from the Mass Spectra of Heterogeneous Protein Assemblies

(2012) Nina Morgner et al.   ANALYTICAL CHEMISTRY

Lipid Bilayer Properties Control Membrane Partitioning, Binding, and Transport of P-Glycoprotein Substrates

(2012) Adam T. Clay et al.   BIOCHEMISTRY

Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria

(2012) E A Roundhill et al.   BRITISH JOURNAL OF CANCER

Charge-State Dependent Compaction and Dissociation of Protein Complexes: Insights from Ion Mobility and Molecular Dynamics

(2012) Zoe Hall et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

(2012) Mi Sun Jin et al.   NATURE

Determining P-glycoprotein–drug interactions: Evaluation of reconstituted P-glycoprotein in a liposomal system and LLC-MDR1 polarized cell monolayers

(2012) Donald L. Melchior et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Design and Synthesis of Selenazole-Containing Peptides for Cocrystallization with P-Glycoprotein

(2011) Houchao Tao et al.   CHEMBIOCHEM

P-glycoprotein Inhibition: The Past, the Present and the Future

(2011) Richard A.J. Darby et al.   CURRENT DRUG METABOLISM

The P-glycoprotein multidrug transporter

(2011) Frances J. Sharom   Essays in Biochemistry

Dynamic Ligand-induced Conformational Rearrangements in P-glycoprotein as Probed by Fluorescence Resonance Energy Transfer Spectroscopy

(2011) Brandy Verhalen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass Spectrometry of Intact V-Type ATPases Reveals Bound Lipids and the Effects of Nucleotide Binding

(2011) M. Zhou et al.   SCIENCE

Collision Cross Sections of Proteins and Their Complexes: A Calibration Framework and Database for Gas-Phase Structural Biology

(2010) Matthew F. Bush et al.   ANALYTICAL CHEMISTRY

Detergents as intrinsic P-glycoprotein substrates and inhibitors

(2009) Xiaochun Li-Blatter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A Multidrug ABC Transporter with a Taste for Salt

(2009) Saroj Velamakanni et al.   PLoS One

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Interaction of the P-Glycoprotein Multidrug Efflux Pump with Cholesterol: Effects on ATPase Activity, Drug Binding and Transport†

(2008) Paul D. W. Eckford et al.   BIOCHEMISTRY

Molecular basis of multidrug transport by ABC transporters

(2008) Markus A. Seeger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cardiolipin, the heart of mitochondrial metabolism

(2008) R. H. Houtkooper et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Micelles Protect Membrane Complexes from Solution to Vacuum

(2008) N. P. Barrera et al.   SCIENCE