Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research
Authors
Keywords
-
Journal
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-02-25
DOI
10.1007/s00424-021-02536-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Probing prodrug metabolism and reciprocal toxicity with an integrated and humanized multi-tissue organ-on-a-chip platform
- (2020) Shiny Amala Priya Rajan et al. Acta Biomaterialia
- Towards chamber specific heart-on-a-chip for drug testing applications
- (2020) Yimu Zhao et al. ADVANCED DRUG DELIVERY REVIEWS
- Heart-on-a-chip Model with Integrated Extra- and Intra-cellular Bioelectronics for Monitoring Cardiac Electrophysiology under Acute Hypoxia
- (2020) Haitao Liu et al. NANO LETTERS
- Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine
- (2020) Elaheh Karbassi et al. Nature Reviews Cardiology
- Calcium Handling Defects and Cardiac Arrhythmia Syndromes
- (2020) Kornél Kistamás et al. Frontiers in Pharmacology
- PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells
- (2020) Yanping Liu et al. Aging-US
- The cell surface marker CD36 selectively identifies matured, mitochondria-rich hPSC-cardiomyocytes
- (2020) Ellen Ngar-Yun Poon et al. CELL RESEARCH
- Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
- (2020) Elisa Giacomelli et al. Cell Stem Cell
- Cardiomyocyte Maturation
- (2020) Yuxuan Guo et al. CIRCULATION RESEARCH
- Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter?
- (2020) John T Barr et al. DRUG METABOLISM AND DISPOSITION
- Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates
- (2020) Suzan J. G. Knottnerus et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A cardiomyocyte show of force: A fluorescent alpha-actinin reporter line sheds light on human cardiomyocyte contractility versus substrate stiffness
- (2020) Marcelo C. Ribeiro et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity
- (2020) G. Palano et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Stem Cell–Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy
- (2020) Forum Kamdar et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Efficient Drug Screening and Nephrotoxicity Assessment on Co-culture Microfluidic Kidney Chip
- (2020) Lei Yin et al. Scientific Reports
- Vascularized cardiac tissue construction with orientation by layer-by-layer method and 3D printer
- (2020) Yoshinari Tsukamoto et al. Scientific Reports
- Muscle and cardiac therapeutic strategies for Duchenne muscular dystrophy: past, present, and future
- (2020) Agnieszka Łoboda et al. Pharmacological Reports
- Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
- (2020) Dries A.M. Feyen et al. Cell Reports
- Perspective on human pluripotent stem cell‐derived cardiomyocytes in heart disease modeling and repair
- (2020) Qiang Li et al. Stem Cells Translational Medicine
- Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics
- (2020) Rebecca-Ann B. Burton et al. iScience
- Microfluidic organ-on-a-chip models of human liver tissue
- (2020) Ehsanollah Moradi et al. Acta Biomaterialia
- Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes
- (2020) Yvonne Sleiman et al. EBioMedicine
- Single-cell RNA-seq and optical electrophysiology of human induced pluripotent stem cell-derived cardiomyocytes reveal discordance between cardiac subtype-associated gene expression patterns and electrophysiological phenotypes
- (2019) Sherri M. Biendarra-Tiegs et al. STEM CELLS AND DEVELOPMENT
- SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes
- (2019) Christopher N Toepfer et al. CIRCULATION RESEARCH
- A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling
- (2019) Yimu Zhao et al. CELL
- Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell
- (2019) Nazish Sayed et al. CARDIOVASCULAR RESEARCH
- Oxygen Management at the Microscale: A Functional Biochip Material with Long-Lasting and Tunable Oxygen Scavenging Properties for Cell Culture Applications
- (2019) Drago Sticker et al. ACS Applied Materials & Interfaces
- Engineered heart tissue models from hiPSC-derived cardiomyocytes and cardiac ECM for disease modeling and drug testing applications
- (2019) Idit Goldfracht et al. Acta Biomaterialia
- User-Friendly and Parallelized Generation of Human Induced Pluripotent Stem Cell-Derived Microtissues in a Centrifugal Heart-on-a-Chip
- (2019) Oliver Schneider et al. TISSUE ENGINEERING PART A
- Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes
- (2019) Sanam Shafaattalab et al. Stem Cell Reports
- Maturation of three-dimensional, hiPSC-derived cardiomyocyte spheroids utilizing cyclic, uniaxial stretch and electrical stimulation
- (2019) Wesley LaBarge et al. PLoS One
- Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
- (2019) Tae-Eun Park et al. Nature Communications
- Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture
- (2019) Mariana A. Branco et al. Scientific Reports
- Bioprinting Approaches to Engineering Vascularized 3D Cardiac Tissues
- (2019) Nazan Puluca et al. Current Cardiology Reports
- Brain-on-a-chip: A history of development and future perspective
- (2019) Seokyoung Bang et al. Biomicrofluidics
- Fatty Acid-Treated Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes Exhibit Adult Cardiomyocyte-Like Energy Metabolism Phenotypes
- (2019) Yuichi Horikoshi et al. Cells
- A heart-on-a-chip platform for online monitoring of contractile behavior via digital image processing and piezoelectric sensing technique
- (2019) Mutsuhito Sakamiya et al. MEDICAL ENGINEERING & PHYSICS
- Reproducing human and cross-species drug toxicities using a Liver-Chip
- (2019) Kyung-Jin Jang et al. Science Translational Medicine
- Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes
- (2019) Berend J. van Meer et al. Nature Communications
- Engineered Liver-on-a-Chip Platform to Mimic Liver Functions and Its Biomedical Applications: A Review
- (2019) Deng et al. Micromachines
- Engineering of Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using Substrates with Multiscale Topography
- (2018) Parisa P. S. S. Abadi et al. ADVANCED FUNCTIONAL MATERIALS
- Aurothioglucose does not improve alveolarization or elicit sustained Nrf2 activation in C57BL/6 models of bronchopulmonary dysplasia
- (2018) Qian Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Can non-clinical repolarization assays predict the results of clinical thorough QT studies? Results from a research consortium
- (2018) Eunjung Park et al. BRITISH JOURNAL OF PHARMACOLOGY
- Kidney-on-a-Chip: A New Technology for Predicting Drug Efficacy, Interactions, and Drug-induced Nephrotoxicity
- (2018) Jeonghwan Lee et al. CURRENT DRUG METABOLISM
- Electrical dysfunctions in human-induced pluripotent stem cell-derived cardiomyocytes from a patient with an arrhythmogenic right ventricular cardiomyopathy
- (2018) Ibrahim El-Battrawy et al. EUROPACE
- Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?
- (2018) Jonathan P Stack et al. EUROPEAN HEART JOURNAL
- Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues
- (2018) Andrea Leonard et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Human brain organoid-on-a-chip to model prenatal nicotine exposure
- (2018) Yaqing Wang et al. LAB ON A CHIP
- Advanced maturation of human cardiac tissue grown from pluripotent stem cells
- (2018) Kacey Ronaldson-Bouchard et al. NATURE
- The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on I K1
- (2018) Birgit Goversen et al. PHARMACOLOGY & THERAPEUTICS
- Cardiac differentiation of pluripotent stem cells and implications for modeling the heart in health and disease
- (2018) Harsha D. Devalla et al. Science Translational Medicine
- Functional video-based analysis of 3D cardiac structures generated from human embryonic stem cells
- (2018) Scarlett Nitsch et al. Stem Cell Research
- Pancreatic Effects of a Bruton’s Tyrosine Kinase Small-molecule Inhibitor in Rats Are Strain-dependent
- (2018) Manoj Bhaskaran et al. TOXICOLOGIC PATHOLOGY
- Expression Profiling of Human Pluripotent Stem Cell-Derived Cardiomyocytes Exposed to Doxorubicin—Integration and Visualization of Multi-Omics Data
- (2018) Gustav Holmgren et al. TOXICOLOGICAL SCIENCES
- Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study
- (2018) Daniel Millard et al. TOXICOLOGICAL SCIENCES
- Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice
- (2018) Zhongyu Li et al. TOXICOLOGY IN VITRO
- Polypyrrole-chitosan conductive biomaterial synchronizes cardiomyocyte contraction and improves myocardial electrical impulse propagation
- (2018) Zhi Cui et al. Theranostics
- Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes
- (2018) David A Knowles et al. eLife
- Conductive silk–polypyrrole composite scaffolds with bioinspired nanotopographic cues for cardiac tissue engineering
- (2018) Jonathan H. Tsui et al. Journal of Materials Chemistry B
- International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
- (2018) Ksenia Blinova et al. Cell Reports
- Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update
- (2018) Yasunari Kanda et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium
- (2018) Marta Lemme et al. Stem Cell Reports
- Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking
- (2018) Ivan Kopljar et al. Stem Cell Reports
- Post-Translational Modifications and Diastolic Calcium Leak Associated to the Novel RyR2-D3638A Mutation Lead to CPVT in Patient-Specific hiPSC-Derived Cardiomyocytes
- (2018) Ivana Acimovic et al. Journal of Clinical Medicine
- A cardiac patch from aligned microvessel and cardiomyocyte patches
- (2017) Jeremy A. Schaefer et al. Journal of Tissue Engineering and Regenerative Medicine
- Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis
- (2017) Arisa Higa et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Simultaneous electrical recording of cardiac electrophysiology and contraction on chip
- (2017) Fang Qian et al. LAB ON A CHIP
- Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening
- (2017) Johan U. Lind et al. LAB ON A CHIP
- Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities
- (2017) Ben M. Maoz et al. LAB ON A CHIP
- Differentiation of cardiomyocytes and generation of human engineered heart tissue
- (2017) Kaja Breckwoldt et al. Nature Protocols
- High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells
- (2017) Arun Sharma et al. Science Translational Medicine
- Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling
- (2017) Oscar J. Abilez et al. STEM CELLS
- Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells
- (2017) Patrick A. Schweizer et al. Stem Cell Research & Therapy
- Current Strategies and Challenges for Purification of Cardiomyocytes Derived from Human Pluripotent Stem Cells
- (2017) Kiwon Ban et al. Theranostics
- Drugs and life-threatening ventricular arrhythmia risk: results from the DARE study cohort
- (2017) Abigail L Coughtrie et al. BMJ Open
- Assessment of extracellular field potential and Ca2+ transient signals for early QT/pro-arrhythmia detection using human induced pluripotent stem cell-derived cardiomyocytes
- (2017) Najah Abi-Gerges et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells
- (2017) Maureen Wanjare et al. Biomaterials Science
- Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features
- (2017) Jaimit Parikh et al. Frontiers in Pharmacology
- Recapitulation of Clinical Individual Susceptibility to Drug-Induced QT Prolongation in Healthy Subjects Using iPSC-Derived Cardiomyocytes
- (2017) Tadahiro Shinozawa et al. Stem Cell Reports
- CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice
- (2017) Yu Zhang et al. Science Advances
- MUSCLEMOTION
- (2017) Luca Sala et al. CIRCULATION RESEARCH
- Biomaterial-Free Three-Dimensional Bioprinting of Cardiac Tissue using Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
- (2017) Chin Siang Ong et al. Scientific Reports
- hiPSC-CM Monolayer Maturation State Determines Drug Responsiveness in High Throughput Pro-Arrhythmia Screen
- (2017) André Monteiro da Rocha et al. Scientific Reports
- From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity: A Translational Overview
- (2017) Carlo Gabriele Tocchetti et al. ANTIOXIDANTS & REDOX SIGNALING
- Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells
- (2016) Daniel Carson et al. ACS Applied Materials & Interfaces
- PNIPAAm-based biohybrid injectable hydrogel for cardiac tissue engineering
- (2016) Ali Navaei et al. Acta Biomaterialia
- Development of vascularized iPSC derived 3D-cardiomyocyte tissues by filtration Layer-by-Layer technique and their application for pharmaceutical assays
- (2016) Yuto Amano et al. Acta Biomaterialia
- Human engineered heart tissue as a model system for drug testing
- (2016) Alexandra Eder et al. ADVANCED DRUG DELIVERY REVIEWS
- Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform
- (2016) Chris Denning et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip
- (2016) Yu Shrike Zhang et al. BIOMATERIALS
- A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices
- (2016) Seyed Ali Mousavi Shaegh et al. Biomicrofluidics
- Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing
- (2016) Martin Pesl et al. BIOSENSORS & BIOELECTRONICS
- Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac TissueClinical Perspective
- (2016) Jia-Ling Ruan et al. CIRCULATION
- Cardio-Oncology
- (2016) Carrie G. Lenneman et al. CIRCULATION RESEARCH
- Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues
- (2016) Anna Marsano et al. LAB ON A CHIP
- Human induced pluripotent stem cell-derived fiber-shaped cardiac tissue on a chip
- (2016) Y. Morimoto et al. LAB ON A CHIP
- Micropost arrays for measuring stem cell-derived cardiomyocyte contractility
- (2016) Kevin M. Beussman et al. METHODS
- Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker
- (2016) Stephanie I Protze et al. NATURE BIOTECHNOLOGY
- Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity
- (2016) Paul W Burridge et al. NATURE MEDICINE
- Validating the pharmacogenomics of chemotherapy-induced cardiotoxicity: What is missing?
- (2016) Tarek Magdy et al. PHARMACOLOGY & THERAPEUTICS
- Three-Dimensional Adult Cardiac Extracellular Matrix Promotes Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
- (2016) Ashley H. Fong et al. TISSUE ENGINEERING PART A
- The Use of Ratiometric Fluorescence Measurements of the Voltage Sensitive Dye Di-4-ANEPPS to Examine Action Potential Characteristics and Drug Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
- (2016) M. P. Hortigon-Vinagre et al. TOXICOLOGICAL SCIENCES
- Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening
- (2016) Martijn J. Wilmer et al. TRENDS IN BIOTECHNOLOGY
- Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes
- (2016) George Eng et al. Nature Communications
- The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative — Update on progress
- (2016) Thomas Colatsky et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Laminar ventricular myocardium on a microelectrode array-based chip
- (2016) Ville J. Kujala et al. Journal of Materials Chemistry B
- Extracellular Recordings of Patterned Human Pluripotent Stem Cell-Derived Cardiomyocytes on Aligned Fibers
- (2016) Junjun Li et al. Stem Cells International
- Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells
- (2016) Damián Hernández et al. Stem Cells International
- Early drug development: assessment of proarrhythmic risk and cardiovascular safety
- (2016) Robert M. Lester et al. Expert Review of Clinical Pharmacology
- Human Engineered Heart Tissue: Analysis of Contractile Force
- (2016) Ingra Mannhardt et al. Stem Cell Reports
- Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs
- (2016) Carlota Oleaga et al. Scientific Reports
- Conductive interpenetrating networks of polypyrrole and polycaprolactone encourage electrophysiological development of cardiac cells
- (2015) Benjamin S. Spearman et al. Acta Biomaterialia
- Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment
- (2015) Umesh Chaudhari et al. ARCHIVES OF TOXICOLOGY
- Dynamics of Cell Generation and Turnover in the Human Heart
- (2015) Olaf Bergmann et al. CELL
- Revisiting Cardiac Cellular CompositionNovelty and Significance
- (2015) Alexander R. Pinto et al. CIRCULATION RESEARCH
- Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology
- (2015) H. D. Devalla et al. EMBO Molecular Medicine
- Modeling structural and functional deficiencies ofRBM20familial dilated cardiomyopathy using human induced pluripotent stem cells
- (2015) Saranya P. Wyles et al. HUMAN MOLECULAR GENETICS
- Stem cell derived in vivo-like human cardiac bodies in a microfluidic device for toxicity testing by beating frequency imaging
- (2015) Gunnar Bergström et al. LAB ON A CHIP
- Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes
- (2015) Kavitha T. Kuppusamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
- (2015) Anurag Mathur et al. Scientific Reports
- Engineering Adolescence
- (2014) Xiulan Yang et al. CIRCULATION RESEARCH
- Differentiating Drug-Induced Multichannel Block on the Electrocardiogram: Randomized Study of Dofetilide, Quinidine, Ranolazine, and Verapamil
- (2014) L Johannesen et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Measuring the Contractile Forces of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Arrays of Microposts
- (2014) Marita L. Rodriguez et al. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
- (2014) Gang Wang et al. NATURE MEDICINE
- Chemically defined generation of human cardiomyocytes
- (2014) Paul W Burridge et al. NATURE METHODS
- Three-Dimensional Extracellular Matrix Scaffolds by Microfluidic Fabrication for Long-Term Spontaneously Contracted Cardiomyocyte Culture
- (2014) Jeng-Chun Mei et al. TISSUE ENGINEERING PART A
- Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium
- (2013) Philip T. Sager et al. AMERICAN HEART JOURNAL
- Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes
- (2013) Donghui Zhang et al. BIOMATERIALS
- Screening Drug-Induced Arrhythmia Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Low-Impedance Microelectrode Arrays
- (2013) E. G. Navarrete et al. CIRCULATION
- Drug Screening Using a Library of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity
- (2013) Ping Liang et al. CIRCULATION
- Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture
- (2013) Tsukasa Kamakura et al. CIRCULATION JOURNAL
- Modeling of Arrhythmogenic Right Ventricular Cardiomyopathy With Human Induced Pluripotent Stem Cells
- (2013) Oren Caspi et al. Circulation-Cardiovascular Genetics
- Educational Paper: Decreasing the burden of cardiovascular disease in childhood cancer survivors: An update for the pediatrician
- (2013) Rejane F. Dillenburg et al. EUROPEAN JOURNAL OF PEDIATRICS
- Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
- (2013) Kyung-Jin Jang et al. Integrative Biology
- Microfluidic heart on a chip for higher throughput pharmacological studies
- (2013) Ashutosh Agarwal et al. LAB ON A CHIP
- Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs
- (2013) Changsung Kim et al. NATURE
- Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes
- (2013) Sara S Nunes et al. NATURE METHODS
- Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity
- (2013) Teresa M. DesRochers et al. PLoS One
- Exon Skipping and Gene Transfer Restore Dystrophin Expression in Human Induced Pluripotent Stem Cells-Cardiomyocytes Harboring DMD Mutations
- (2013) Emily Dick et al. STEM CELLS AND DEVELOPMENT
- In-vitro perfusion of engineered heart tissue through endothelialized channels
- (2013) Ingra Vollert et al. TISSUE ENGINEERING PART A
- 3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies
- (2013) Patrina Gunness et al. TOXICOLOGICAL SCIENCES
- CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia
- (2013) E Di Pasquale et al. Cell Death & Disease
- Comparison of Biocompatibility and Adsorption Properties of Different Plastics for Advanced Microfluidic Cell and Tissue Culture Models
- (2012) Paul M. van Midwoud et al. ANALYTICAL CHEMISTRY
- Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip
- (2012) Leila Choucha-Snouber et al. BIOTECHNOLOGY AND BIOENGINEERING
- In vitro 3D human small intestinal villous model for drug permeability determination
- (2012) Jiajie Yu et al. BIOTECHNOLOGY AND BIOENGINEERING
- Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes
- (2012) Shugo Tohyama et al. Cell Stem Cell
- Animal Models of Heart Failure
- (2012) Steven R. Houser et al. CIRCULATION RESEARCH
- Optical Imaging of Voltage and Calcium in Cardiac Cells & Tissues
- (2012) Todd J. Herron et al. CIRCULATION RESEARCH
- Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes
- (2012) Christine L. Mummery et al. CIRCULATION RESEARCH
- Modeling of Catecholaminergic Polymorphic Ventricular Tachycardia With Patient-Specific Human-Induced Pluripotent Stem Cells
- (2012) Ilanit Itzhaki et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions
- (2012) Xiaojun Lian et al. Nature Protocols
- Atomic Force Mechanobiology of Pluripotent Stem Cell-Derived Cardiomyocytes
- (2012) Jianwei Liu et al. PLoS One
- Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
- (2012) N. Sun et al. Science Translational Medicine
- Muscle on a chip: In vitro contractility assays for smooth and striated muscle
- (2012) Anna Grosberg et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Growth of Engineered Human Myocardium With Mechanical Loading and Vascular Coculture
- (2011) Nathaniel L. Tulloch et al. CIRCULATION RESEARCH
- Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
- (2011) Christian B. Jung et al. EMBO Molecular Medicine
- Reversible alteration of calcium dynamics in cardiomyocytes during acute hypoxia transient in a microfluidic platform
- (2011) S. Martewicz et al. Integrative Biology
- SCN5A Mutations Associate With Arrhythmic Dilated Cardiomyopathy and Commonly Localize to the Voltage-Sensing Mechanism
- (2011) William P. McNair et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Modelling the long QT syndrome with induced pluripotent stem cells
- (2011) Ilanit Itzhaki et al. NATURE
- A Universal System for Highly Efficient Cardiac Differentiation of Human Induced Pluripotent Stem Cells That Eliminates Interline Variability
- (2011) Paul W. Burridge et al. PLoS One
- Integrated Proteomic and Transcriptomic Investigation of the Acetaminophen Toxicity in Liver Microfluidic Biochip
- (2011) Jean Matthieu Prot et al. PLoS One
- Biohybrid thin films for measuring contractility in engineered cardiovascular muscle
- (2010) Patrick W. Alford et al. BIOMATERIALS
- Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome
- (2010) Alessandra Moretti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Can Animal Models of Disease Reliably Inform Human Studies?
- (2010) H. Bart van der Worp et al. PLOS MEDICINE
- In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
- (2009) Tomofumi Tanaka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nongenetic method for purifying stem cell–derived cardiomyocytes
- (2009) Fumiyuki Hattori et al. NATURE METHODS
- Electrical stimulation systems for cardiac tissue engineering
- (2009) Nina Tandon et al. Nature Protocols
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started