Human brain organoid-on-a-chip to model prenatal nicotine exposure

Probing impaired neurogenesis in human brain organoids exposed to alcohol

(2017) Yujuan Zhu et al.   Integrative Biology

In situ generation of human brain organoids on a micropillar array

(2017) Yujuan Zhu et al.   LAB ON A CHIP

Bioinspired onion epithelium-like structure promotes the maturation of cardiomyocytes derived from human pluripotent stem cells

(2017) Cong Xu et al.   Biomaterials Science

Functional engineered human cardiac patches prepared from nature's platform improve heart function after acute myocardial infarction

(2016) Qingjie Wang et al.   BIOMATERIALS

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Engineering a perfusable 3D human liver platform from iPS cells

(2016) Arnout Schepers et al.   LAB ON A CHIP

The promises and challenges of human brain organoids as models of neuropsychiatric disease

(2016) Giorgia Quadrato et al.   NATURE MEDICINE

CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit

(2016) Chun-Ting Lee et al.   NEUROPSYCHOPHARMACOLOGY

Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain

(2016) Chongyuan Luo et al.   Cell Reports

Human induced pluripotent stem cell-derived beating cardiac tissues on paper

(2015) Li Wang et al.   LAB ON A CHIP

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex

(2015) Yuki Aoyama et al.   NEUROPSYCHOPHARMACOLOGY

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

How unique is the human neocortex?

(2013) Z. Molnar et al.   DEVELOPMENT

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Environmental tobacco smoke exposure and brain development: The case of attention deficit/hyperactivity disorder

(2013) Linda S. Pagani   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

(2013) T. Kadoshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of emotional behaviors in young offspring of C57BL/6J mice after gestational and/or perinatal exposure to nicotine in six different time-windows

(2012) Tursun Alkam et al.   BEHAVIOURAL BRAIN RESEARCH

Prenatal Nicotine Exposure Mouse Model Showing Hyperactivity, Reduced Cingulate Cortex Volume, Reduced Dopamine Turnover, and Responsiveness to Oral Methylphenidate Treatment

(2012) J. Zhu et al.   JOURNAL OF NEUROSCIENCE

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Modeling human cortical development in vitro using induced pluripotent stem cells

(2012) J. Mariani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers

(2011) Jean-Michel Peyrin et al.   LAB ON A CHIP

The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels

(2011) Martine N Manuel et al.   Neural Development

Prenatal Exposure to Nicotine Impairs Performance of the 5-Choice Serial Reaction Time Task in Adult Rats

(2011) Tomasz Schneider et al.   NEUROPSYCHOPHARMACOLOGY

Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain

(2011) Sonja C. Vernes et al.   PLoS Genetics

Cytoarchitecture of mouse and human subventricular zone in developing cerebral neocortex

(2011) Hidenori Tabata et al.   EXPERIMENTAL BRAIN RESEARCH

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells

(2009) N. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal tobacco smoking, nicotine replacement and neurobehavioural development

(2008) James R Pauly et al.   ACTA PAEDIATRICA

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell

Facilitation of Cortico–Amygdala Synapses by Nicotine: Activity-Dependent Modulation of Glutamatergic Transmission

(2008) Li Jiang et al.   JOURNAL OF NEUROPHYSIOLOGY

Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons

(2008) R. Satta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA