Expression Profiling of Human Pluripotent Stem Cell-Derived Cardiomyocytes Exposed to Doxorubicin—Integration and Visualization of Multi-Omics Data

MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes

(2016) Umesh Chaudhari et al.   ARCHIVES OF TOXICOLOGY

New signal transduction paradigms in anthracycline-induced cardiotoxicity

(2016) Alessandra Ghigo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Resveratrol-induced autophagy promotes survival and attenuates doxorubicin-induced cardiotoxicity

(2016) Jun Gu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

(2016) Paul W Burridge et al.   NATURE MEDICINE

f-divergence cutoff index to simultaneously identify differential expression in the integrated transcriptome and proteome

(2016) Shaojun Tang et al.   NUCLEIC ACIDS RESEARCH

Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases

(2016) Yuhei Nishimura et al.   Oxidative Medicine and Cellular Longevity

Integrative methods for analyzing big data in precision medicine

(2016) Vladimir Gligorijević et al.   PROTEOMICS

Early transcriptional changes in cardiac mitochondria during chronic doxorubicin exposure and mitigation by dexrazoxane in mice

(2016) Vikrant Vijay et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNAs as potential biomarkers for doxorubicin-induced cardiotoxicity

(2016) Gustav Holmgren et al.   TOXICOLOGY IN VITRO

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes

(2016) Agnes Maillet et al.   Scientific Reports

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment

(2015) Umesh Chaudhari et al.   ARCHIVES OF TOXICOLOGY

Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy

(2015) D. Cardinale et al.   CIRCULATION

Cardiac hypertrophy reduction in SHR by specific silencing of myocardial Na+/H+ exchanger

(2015) Mariela B. Nolly et al.   JOURNAL OF APPLIED PHYSIOLOGY

Resveratrol protects cardiomyocytes from doxorubicin-induced apoptosis through the AMPK/P53 pathway

(2015) MI-HUA LIU et al.   Molecular Medicine Reports

Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells

(2015) Gustav Holmgren et al.   TOXICOLOGY

Na+/H+ Exchanger Isoform 1-Induced Osteopontin Expression Facilitates Cardiomyocyte Hypertrophy

(2015) Iman A. Mohamed et al.   PLoS One

Na+/H+ Exchanger Isoform 1 Induced Cardiomyocyte Hypertrophy Involves Activation of p90 Ribosomal S6 Kinase

(2015) Maiy Jaballah et al.   PLoS One

The National Institutes of Health's Big Data to Knowledge (BD2K) initiative: capitalizing on biomedical big data

(2014) Ronald Margolis et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

Metformin Protects Cardiomyocyte from Doxorubicin Induced Cytotoxicity through an AMP-Activated Protein Kinase Dependent Signaling Pathway: An In Vitro Study

(2014) Laura C. Kobashigawa et al.   PLoS One

Examining the Protective Role of ErbB2 Modulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2014) Sandy Eldridge et al.   TOXICOLOGICAL SCIENCES

Pathway-based visualization of cross-platform microarray datasets

(2012) C. Wrzodek et al.   BIOINFORMATICS

InCroMAP: integrated analysis of cross-platform microarray and pathway data

(2012) C. Wrzodek et al.   BIOINFORMATICS

Inhibition of AMP-activated Protein Kinase α (AMPKα) by Doxorubicin Accentuates Genotoxic Stress and Cell Death in Mouse Embryonic Fibroblasts and Cardiomyocytes

(2012) Shaobin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass

(2010) Deise Raquel Barpe et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

(2009) Paul J Boersema et al.   Nature Protocols