Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues

Effects of Physiologic Mechanical Stimulation on Embryonic Chick Cardiomyocytes Using a Microfluidic Cardiac Cell Culture Model

(2015) Mai-Dung Nguyen et al.   ANALYTICAL CHEMISTRY

On-chip assessment of human primary cardiac fibroblasts proliferative responses to uniaxial cyclic mechanical strain

(2015) Giovanni Stefano Ugolini et al.   BIOTECHNOLOGY AND BIOENGINEERING

Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales

(2015) Nathaniel Huebsch et al.   TISSUE ENGINEERING PART C-METHODS

Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

(2015) Anurag Mathur et al.   Scientific Reports

Controlled electromechanical cell stimulation on-a-chip

(2015) Andrea Pavesi et al.   Scientific Reports

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

Bioengineering heart tissue for in vitro testing

(2013) Elisa Cimetta et al.   CURRENT OPINION IN BIOTECHNOLOGY

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium

(2013) Irene C. Turnbull et al.   FASEB JOURNAL

Lessons from the heart: Mirroring electrophysiological characteristics during cardiac development to in vitro differentiation of stem cell derived cardiomyocytes

(2013) Nikki H.L. van den Heuvel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Microfluidic heart on a chip for higher throughput pharmacological studies

(2013) Ashutosh Agarwal et al.   LAB ON A CHIP

Cardiac-like flow generator for long-term imaging of endothelial cell responses to circulatory pulsatile flow at microscale

(2013) Huaying Chen et al.   LAB ON A CHIP

Design and formulation of functional pluripotent stem cell-derived cardiac microtissues

(2013) N. Thavandiran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microsystems for biomimetic stimulation of cardiac cells

(2012) Chelsey S. Simmons et al.   LAB ON A CHIP

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impedance-Based Detection of Beating Rhythm and Proarrhythmic Effects of Compounds on Stem Cell-Derived Cardiomyocytes

(2011) Malin K.B. Jonsson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Valve-based microfluidic compression platform: single axon injury and regrowth

(2011) Suneil Hosmane et al.   LAB ON A CHIP

Engineered approaches to the stem cell microenvironment for cardiac tissue regeneration

(2011) Ebrahim Ghafar-Zadeh et al.   LAB ON A CHIP

The Effects of Mechanical Stress on the Growth, Differentiation, and Paracrine Factor Production of Cardiac Stem Cells

(2011) Hiroshi Kurazumi et al.   PLoS One

Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology

(2011) Sebastian Schaaf et al.   PLoS One

A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues

(2011) Thomas Boudou et al.   TISSUE ENGINEERING PART A

Scaffold stiffness affects the contractile function of three-dimensional engineered cardiac constructs

(2010) Anna Marsano et al.   BIOTECHNOLOGY PROGRESS

Cyclic Mechanical Stretch Induces Cardiomyocyte Orientation and Polarization of the Gap Junction Protein Connexin43

(2010) Aida Salameh et al.   CIRCULATION RESEARCH

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Thickness-dependent mechanical properties of polydimethylsiloxane membranes

(2009) Miao Liu et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

(2009) Carlos P. Huang et al.   LAB ON A CHIP

Electrical stimulation systems for cardiac tissue engineering

(2009) Nina Tandon et al.   Nature Protocols

Deformation of PDMS membrane and microcantilever by a water droplet: Comparison between Mooney–Rivlin and linear elastic constitutive models

(2008) Ying-Song Yu et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Cardiac tissue engineering using perfusion bioreactor systems

(2008) Milica Radisic et al.   Nature Protocols