Advanced maturation of human cardiac tissue grown from pluripotent stem cells

Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues

(2017) Ilya Y. Shadrin et al.   Nature Communications

Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues

(2016) Nicole T. Feric et al.   ADVANCED DRUG DELIVERY REVIEWS

Dynamic culture yields engineered myocardium with near-adult functional output

(2016) Christopher P. Jackman et al.   BIOMATERIALS

Human Engineered Heart Tissue: Analysis of Contractile Force

(2016) Ingra Mannhardt et al.   Stem Cell Reports

Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses

(2016) Nathaniel Huebsch et al.   Scientific Reports

Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro – Correlation between contraction force and electrophysiology

(2015) Marcelo C. Ribeiro et al.   BIOMATERIALS

Maintaining Ancient Organelles: Mitochondrial Biogenesis and Maturation

(2015) R. B. Vega et al.   CIRCULATION RESEARCH

Mitochondria shape cardiac metabolism

(2015) R. A. Gottlieb et al.   SCIENCE

Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

(2015) G. Gong et al.   SCIENCE

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

(2014) TingTing Hong et al.   NATURE MEDICINE

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

Human Stem Cells for Modeling Heart Disease and for Drug Discovery

(2014) E. Matsa et al.   Science Translational Medicine

Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

(2013) Sara S Nunes et al.   NATURE METHODS

Structural and Functional Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells

(2013) Scott D. Lundy et al.   STEM CELLS AND DEVELOPMENT

Induced pluripotent stem cells: the new patient?

(2012) Milena Bellin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

(2011) Junyi Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Growth of Engineered Human Myocardium With Mechanical Loading and Vascular Coculture

(2011) Nathaniel L. Tulloch et al.   CIRCULATION RESEARCH

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

(2011) Masayuki Yazawa et al.   NATURE

Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation

(2010) Gary D Lopaschuk et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition

(2010) Ryan Sun et al.   Biomedical Optics Express

Force Frequency Relationship of the Human Ventricle Increases During Early Postnatal Development

(2009) Rob F Wiegerinck et al.   PEDIATRIC RESEARCH

Generation of Functional Ventricular Heart Muscle from Mouse Ventricular Progenitor Cells

(2009) I. J. Domian et al.   SCIENCE