Can Animal Models of Disease Reliably Inform Human Studies?

Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

(2010) Emily S. Sena et al.   PLOS BIOLOGY

Emulating Multicentre Clinical Stroke Trials: A New Paradigm for Studying Novel Interventions in Experimental Models of Stroke

(2009) P. M. W. Bath et al.   International Journal of Stroke

Systematic Review and Stratified Meta-analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke

(2009) Victoria Banwell et al.   Journal of Stroke & Cerebrovascular Diseases

Launching invasive, first-in-human trials against Parkinson's disease: Ethical considerations

(2009) Jonathan Kimmelman et al.   MOVEMENT DISORDERS

Design, power, and interpretation of studies in the standard murine model of ALS

(2008) Sean Scott et al.   Amyotrophic Lateral Sclerosis

Early complications of ischemic stroke

(2008) H. Bart van der Worp et al.   Current Treatment Options in Neurology

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial

(2008) Marc GH Besselink et al.   LANCET

Intrauterine Growth Restriction in a Rodent Model and Developmental Programming of the Metabolic Syndrome: A Critical Appraisal of the Experimental Evidence

(2008) U. Neitzke et al.   PLACENTA

Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias

(2008) Kerry Dwan et al.   PLoS One

Evidence for the Efficacy of NXY-059 in Experimental Focal Cerebral Ischaemia Is Confounded by Study Quality

(2008) Malcolm R. Macleod et al.   STROKE

Empirical Evidence of Bias in the Design of Experimental Stroke Studies

(2008) Nicolas A. Crossley et al.   STROKE

Good Laboratory Practice

(2008) Malcolm R. Macleod et al.   STROKE

Progesterone for the treatment of experimental brain injury; a systematic review

(2007) C. L. Gibson et al.   BRAIN