Chemically defined generation of human cardiomyocytes

Human Stem Cells for Modeling Heart Disease and for Drug Discovery

(2014) E. Matsa et al.   Science Translational Medicine

Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment

(2014) Sergey Rodin et al.   Nature Communications

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

(2013) Kathryn Blaschke et al.   NATURE

Human Embryonic Stem Cell-Derived Cardiomyocytes Migrate in Response to Gradients of Fibronectin and Wnt5a

(2013) Kara White Moyes et al.   STEM CELLS AND DEVELOPMENT

Functional Diversity of Laminins

(2012) Anna Domogatskaya et al.   Annual Review of Cell and Developmental Biology

Small Molecule-Mediated TGF-β Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells

(2012) Erik Willems et al.   Cell Stem Cell

Production of De Novo Cardiomyocytes: Human Pluripotent Stem Cell Differentiation and Direct Reprogramming

(2012) Paul W. Burridge et al.   Cell Stem Cell

Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes

(2012) Shugo Tohyama et al.   Cell Stem Cell

Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells

(2012) Jianhua Zhang et al.   CIRCULATION RESEARCH

Intracellular recording of action potentials by nanopillar electroporation

(2012) Chong Xie et al.   Nature Nanotechnology

Microbioreactor Arrays for Full Factorial Screening of Exogenous and Paracrine Factors in Human Embryonic Stem Cell Differentiation

(2012) Drew M. Titmarsh et al.   PLoS One

Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

(2012) X. Lian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells

(2012) Takamichi Miyazaki et al.   Nature Communications

A Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Conditions

(2012) Itsunari Minami et al.   Cell Reports

Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells

(2011) Nan Cao et al.   CELL RESEARCH

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

(2011) Bin-Kuan Chou et al.   CELL RESEARCH

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

(2011) Steven J. Kattman et al.   Cell Stem Cell

NKX2-5 eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

(2011) David A Elliott et al.   NATURE METHODS

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

A Universal System for Highly Efficient Cardiac Differentiation of Human Induced Pluripotent Stem Cells That Eliminates Interline Variability

(2011) Paul W. Burridge et al.   PLoS One

Efficient and Scalable Purification of Cardiomyocytes from Human Embryonic and Induced Pluripotent Stem Cells by VCAM1 Surface Expression

(2011) Hideki Uosaki et al.   PLoS One

Efficient Differentiation of Human Induced Pluripotent Stem Cells Generates Cardiac Cells That Provide Protection Following Myocardial Infarction in the Rat

(2011) Lee Carpenter et al.   STEM CELLS AND DEVELOPMENT

Differential gene expressions in atrial and ventricular myocytes: insights into the road of applying embryonic stem cell-derived cardiomyocytes for future therapies

(2010) Sze Ying Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum

(2010) Masato Nagaoka et al.   BMC DEVELOPMENTAL BIOLOGY

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

(2010) Qiangzhe Zhang et al.   CELL RESEARCH

Albumin and mammalian cell culture: implications for biotechnology applications

(2010) Geoffrey L. Francis   CYTOTECHNOLOGY

Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells

(2010) Zara Melkoumian et al.   NATURE BIOTECHNOLOGY

Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511

(2010) Sergey Rodin et al.   NATURE BIOTECHNOLOGY

Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells

(2010) Sharon L. Paige et al.   PLoS One

Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes

(2010) Prashant Mali et al.   STEM CELLS

Defining a Threshold Surface Density of Vitronectin for the Stable Expansion of Human Embryonic Stem Cells

(2010) Lynn Y.W. Yap et al.   TISSUE ENGINEERING PART C-METHODS

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

(2009) Noemi FUSAKI et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

(2008) Elizabeth S Ng et al.   Nature Protocols

Recombinant Vitronectin Is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self-Renewal via αVβ5 Integrin

(2008) Stefan R. Braam et al.   STEM CELLS

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK

(2007) Ralph Graichen et al.   DIFFERENTIATION