The Use of Ratiometric Fluorescence Measurements of the Voltage Sensitive Dye Di-4-ANEPPS to Examine Action Potential Characteristics and Drug Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology

(2016) Aleksandra Klimas et al.   Nature Communications

Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging

(2016) Graham T. Dempsey et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Action Potential Morphology of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Does Not Predict Cardiac Chamber Specificity and Is Dependent on Cell Density

(2015) David T.M. Du et al.   BIOPHYSICAL JOURNAL

High Throughput Measurement of Ca++Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment Characterization Using a Large Panel of Cardioactive and Inactive Compounds

(2015) Hua Rong Lu et al.   TOXICOLOGICAL SCIENCES

Comprehensive T wave Morphology Assessment in a Randomized Clinical Study of Dofetilide, Quinidine, Ranolazine, and Verapamil

(2015) J. Vicente et al.   Journal of the American Heart Association

Action Potential Characterization of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Using Automated Patch-Clamp Technology

(2014) Olaf Scheel et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium

(2013) Philip T. Sager et al.   AMERICAN HEART JOURNAL

Computational Models of Ventricular- and Atrial-Like Human Induced Pluripotent Stem Cell Derived Cardiomyocytes

(2013) Michelangelo Paci et al.   ANNALS OF BIOMEDICAL ENGINEERING

Electronic “expression” of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells

(2013) Glenna C.L. Bett et al.   HEART RHYTHM

Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG

(2012) Malin K.B. Jonsson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

(2011) Junyi Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations

(2011) Tamás Szél et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models

(2011) Udo Kraushaar et al.   Expert Opinion On Drug Safety

Electrophysiological Characterization of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2011) Masaki Honda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Re-Evaluation of the Action Potential Upstroke Velocity as a Measure of the Na+ Current in Cardiac Myocytes at Physiological Conditions

(2011) Géza Berecki et al.   PLoS One

Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation

(2011) Thomas O'Hara et al.   PLoS Computational Biology

Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes

(2010) Malin K.B. Jonsson et al.   Stem Cell Research

The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

(2010) Shengde Peng et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Use-dependent block of cardiac late Na+ current by ranolazine

(2009) Sridharan Rajamani et al.   HEART RHYTHM