Current analytical methods for determination of glucosinolates in vegetables and human tissues

Study of solvent effect on the stability of isothiocyanate iberin, a breakdown product of glucoiberin

(2020) Roberto Cirilli et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Glucosinolates: Natural Occurrence, Biosynthesis, Accessibility, Isolation, Structures, and Biological Activities

(2020) V. P. Thinh Nguyen et al.   MOLECULES

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)

(2019) Valentina Citi et al.   PHYTOTHERAPY RESEARCH

Inhibition of Tumor Growth by Dietary Indole-3-Carbinol in a Prostate Cancer Xenograft Model May Be Associated with Disrupted Gut Microbial Interactions

(2019) Yanbei Wu et al.   Nutrients

Bioavailability of broccoli sprouts in different human overweight populations

(2019) Débora Villaño et al.   Journal of Functional Foods

Profiling glucosinolate metabolites in human urine and plasma after broccoli consumption using non-targeted and targeted metabolomic analyses

(2019) Jianghao Sun et al.   FOOD CHEMISTRY

Glucosinolate structural diversity, identification, chemical synthesis and metabolism in plants

(2019) Ivica Blažević et al.   PHYTOCHEMISTRY

Identification and analysis of a mercapturic acid conjugate of indole-3-methyl isothiocyanate in the urine of humans who consumed cruciferous vegetables

(2018) Pramod Upadhyaya et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cruciferous Vegetables and Risk of Cancers of the Gastrointestinal Tract

(2018) Ian T. Johnson   MOLECULAR NUTRITION & FOOD RESEARCH

Bioavailability of Glucoraphanin and Sulforaphane from High-Glucoraphanin Broccoli

(2018) Tharsini Sivapalan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Separation and Quantification of Four Main Chiral Glucosinolates in Radix Isatidis and Its Granules Using High-Performance Liquid Chromatography/Diode Array Detector Coupled with Circular Dichroism Detection

(2018) Yanhong Shi et al.   MOLECULES

Chromatographic column evaluation for the untargeted profiling of glucosinolates in cauliflower by means of ultra-high performance liquid chromatography coupled to high resolution mass spectrometry

(2018) Anna Laura Capriotti et al.   TALANTA

Differences in Thermal Stability of Glucosinolates in Five Brassica Vegetables

(2018) M. Dekker et al.   CZECH JOURNAL OF FOOD SCIENCES

Supercritical CO2 Extraction of Eruca sativa Using Cosolvents: Phytochemical Composition by LC-MS Analysis

(2018) Stefania Sut et al.   MOLECULES

Simultaneous direct determination of 15 glucosinolates in eight Brassica species by UHPLC-Q-Orbitrap-MS

(2018) In Min Hwang et al.   FOOD CHEMISTRY

Quantification and bioaccessibility of intact glucosinolates in broccoli ‘Parthenon’ and Savoy cabbage ‘Dama’

(2017) Ana María Fernández-León et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Development of an efficient glucosinolate extraction method

(2017) T. Doheny-Adams et al.   Plant Methods

Harnessing the Power of Cruciferous Vegetables: Developing a Biomarker for Brassica Vegetable Consumption Using Urinary 3,3'-Diindolylmethane

(2016) N. Fujioka et al.   Cancer Prevention Research

GLS-Finder: A Platform for Fast Profiling of Glucosinolates in Brassica Vegetables

(2016) Jianghao Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Development of a liquid chromatography–electrospray ionization–tandem mass spectrometry method for the simultaneous analysis of intact glucosinolates and isothiocyanates in Brassicaceae seeds and functional foods

(2016) P. Franco et al.   JOURNAL OF CHROMATOGRAPHY A

Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism

(2016) Peter Felker et al.   NUTRITION REVIEWS

Glucosinolate diversity within a phylogenetic framework of the tribe Cardamineae (Brassicaceae) unraveled with HPLC-MS/MS and NMR-based analytical distinction of 70 desulfoglucosinolates

(2016) Carl Erik Olsen et al.   PHYTOCHEMISTRY

Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism

(2016) Jinyun Liu et al.   Oncotarget

4(α-l-Rhamnosyloxy)-benzyl isothiocyanate, a bioactive phytochemical that attenuates secondary damage in an experimental model of spinal cord injury

(2015) Sabrina Giacoppo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Development of a reliable extraction and quantification method for glucosinolates in Moringa oleifera

(2015) Nadja Förster et al.   FOOD CHEMISTRY

Fast determination of intact glucosinolates in broccoli leaf by pressurized liquid extraction and ultra high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry

(2015) Ana M. Ares et al.   FOOD RESEARCH INTERNATIONAL

Comparison of Glucosinolate Profiles in Different Tissues of Nine Brassica Crops

(2015) Shiva Bhandari et al.   MOLECULES

Dietary Factors Affecting Thyroid Cancer Risk: A Meta-Analysis

(2015) Young Ae Cho et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Myrosinase in Brassicaceae: the most important issue for glucosinolate turnover and food quality

(2015) Maria del Carmen Martinez-Ballesta et al.   PHYTOCHEMISTRY REVIEWS

Enhancement of microwave-assisted extraction of bioactive compounds from cabbage outer leaves via the application of ultrasonic pretreatment

(2015) Patsaporn Pongmalai et al.   SEPARATION AND PURIFICATION TECHNOLOGY

Development and validation of an LC-APCI-MS/MS method for the determination of phenethyl isothiocyanate in human plasma

(2014) Li. Zheng et al.   BIOMEDICAL CHROMATOGRAPHY

Glucosinolate metabolism, functionality and breeding for the improvement of Brassicaceae vegetables

(2014) Masahiko Ishida et al.   BREEDING SCIENCE

Could Nitrile Derivatives of Turnip (Brassica rapa) Glucosinolates Be Hepato- or Cholangiotoxic in Cattle?

(2014) Mark G. Collett et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Development and validation of an HPLC method for the simultaneous quantification of indole-3-carbinol acetate, indole-3-carbinol, and 3,3′-diindolylmethane in mouse plasma, liver, and kidney tissues

(2014) Justin Moussata et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Sinigrin and sinalbin quantification in mustard seed using high performance liquid chromatography–time-of-flight mass spectrometry

(2014) Inna E. Popova et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

‘Moringa oleifera: study of phenolics and glucosinolates by mass spectrometry’

(2014) Mariateresa Maldini et al.   JOURNAL OF MASS SPECTROMETRY

Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway

(2014) Palanisamy Nallasamy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Effects of Conventional and Non-conventional Processing on Glucosinolates and Its Derived Forms, Isothiocyanates: Extraction, Degradation, and Applications

(2014) Qian Deng et al.   Food Engineering Reviews

Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.)

(2013) Stefanie Platz et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Urinary 3,3'-Diindolylmethane: A Biomarker of Glucobrassicin Exposure and Indole-3-Carbinol Uptake in Humans

(2013) N. Fujioka et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Optimized extraction, separation and quantification of twelve intact glucosinolates in broccoli leaves

(2013) Ana M. Ares et al.   FOOD CHEMISTRY

A new ultra-rapid UHPLC/MS/MS method for assessing glucoraphanin and sulforaphane bioavailability in human urine

(2013) Raul Dominguez-Perles et al.   FOOD CHEMISTRY

Myrosinase activity in different plant samples; optimisation of measurement conditions for spectrophotometric and pH-stat methods

(2013) Anna Piekarska et al.   INDUSTRIAL CROPS AND PRODUCTS

Evaluation of Glucosinolate Variation in a Collection of Turnip (Brassica rapa) Germplasm by the Analysis of Intact and Desulfo Glucosinolates

(2013) Jun Gu Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α

(2013) Wei Deng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease

(2013) Fabiana Morroni et al.   NEUROTOXICOLOGY

Metastasis of Breast Tumor Cells to Brain Is Suppressed by Phenethyl Isothiocyanate in a Novel In Vivo Metastasis Model

(2013) Parul Gupta et al.   PLoS One

Characterisation of taste-active extracts from raw Brassica oleracea vegetables

(2013) Dimitrios Zabaras et al.   Food & Function

Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model

(2012) Hyunjin Vincent Kim et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Effect of ethanol treatment on quality and antioxidant activity in postharvest broccoli florets

(2012) Feng Xu et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Neuroprotective Effects of Erucin against 6-Hydroxydopamine-Induced Oxidative Damage in a Dopaminergic-like Neuroblastoma Cell Line

(2012) Andrea Tarozzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantitative profiling of glucosinolates by LC–MS analysis reveals several cultivars of cabbage and kale as promising sources of sulforaphane

(2012) Katsunori Sasaki et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A liquid chromatography-mass spectrometry approach to study “glucosinoloma” in broccoli sprouts

(2012) Mariateresa Maldini et al.   JOURNAL OF MASS SPECTROMETRY

Indole-3-carbinol blocks platelet-derived growth factor-stimulated vascular smooth muscle cell function and reduces neointima formation in vivo

(2012) Hongjing Guan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Glucosinolate structures in evolution

(2012) Niels Agerbirk et al.   PHYTOCHEMISTRY

Identification, quantification and comparison of the principal bioactive compounds and external quality parameters of two broccoli cultivars

(2012) M.F. Fernández-León et al.   Journal of Functional Foods

Pressurized liquid extraction as a green approach in food and herbal plants extraction: A review

(2011) Arwa Mustafa et al.   ANALYTICA CHIMICA ACTA

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

LC-MS/MS Quantification of Sulforaphane and Indole-3-carbinol Metabolites in Human Plasma and Urine after Dietary Intake of Selenium-Fortified Broccoli

(2011) Johanna Hauder et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design

(2011) John D. Clarke et al.   PHARMACOLOGICAL RESEARCH

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

Glucosinolates, structures and analysis in food

(2010) Don Brian Clarke   Analytical Methods

Chiral Separations

(2010) A.M. Stalcup   Annual Review of Analytical Chemistry

Protective Effect of Sulforaphane on Human Vascular Endothelial Cells Against Lipopolysaccharide-Induced Inflammatory Damage

(2010) Yujuan Shan et al.   Cardiovascular Toxicology

Glucosinolates: The synthetic approach

(2010) Patrick Rollin et al.   COMPTES RENDUS CHIMIE

Determination of Glucosinolates and Their Decomposition Products—Indoles and Isothiocyanates in Cruciferous Vegetables

(2010) Anna Śmiechowska et al.   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY

Identification and quantitative determination of glucosinolates in seeds and edible parts of Korean Chinese cabbage

(2010) Eunyoung Hong et al.   FOOD CHEMISTRY

Effect of Different Cooking Methods on Color, Phytochemical Concentration, and Antioxidant Capacity of Raw and Frozen Brassica Vegetables

(2010) Nicoletta Pellegrini et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Optimization of ultrasonic-stimulated solvent extraction of sinigrin from Indian mustard seed (Brassica Juncea L.) using response surface methodology

(2010) Tianxin Wang et al.   PHYTOCHEMICAL ANALYSIS

Identification and quantification of glucosinolates in rapeseed using liquid chromatography–ion trap mass spectrometry

(2009) Silvia Millán et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ascorbigen: chemistry, occurrence, and biologic properties

(2009) Anika E. Wagner et al.   CLINICS IN DERMATOLOGY

Simultaneous evaluation of intact glucosinolates and phenolic compounds by UPLC-DAD-MS/MS in Brassica oleracea L. var. botrytis

(2009) M. Gratacós-Cubarsí et al.   FOOD CHEMISTRY

Modulation of Phase II Enzymes by Sulforaphane: Implications for Its Cardioprotective Potential

(2009) Cristina Angeloni et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Simultaneous identification of glucosinolates and phenolic compounds in a representative collection of vegetable Brassica rapa

(2009) Marta Francisco et al.   JOURNAL OF CHROMATOGRAPHY A

Phase 2 enzyme inducer sulphoraphane blocks matrix metalloproteinase production in articular chondrocytes

(2009) H. Ah Kim et al.   RHEUMATOLOGY

The synthesis of novel hexa-13C-labelled glucosinolates from [13C6]-d-glucose

(2009) Qingzhi Zhang et al.   TETRAHEDRON

Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health

(2008) Ruud Verkerk et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Rapid screening method for intact glucosinolates in Chinese medicinal herbs by using liquid chromatography coupled with electrospray ionization ion trap mass spectrometry in negative ion mode

(2008) Kim-Chung Lee et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Sulforaphane protects against cytokine- and streptozotocin-induced β-cell damage by suppressing the NF-κB pathway

(2008) Mi-Young Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Red Cabbage (Brassica oleracea) Ameliorates Diabetic Nephropathy in Rats

(2007) Hazem A. H. Kataya et al.   Evidence-based Complementary and Alternative Medicine

Applications and opportunities for ultrasound assisted extraction in the food industry — A review

(2007) Kamaljit Vilkhu et al.   Innovative Food Science & Emerging Technologies