Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α

Stem Cell Antigen 1 Protects Against Cardiac Hypertrophy and Fibrosis After Pressure Overload

(2012) Heng Zhou et al.   HYPERTENSION

Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice

(2012) Youngshim Choi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance

(2012) Nicole Metes-Kosik et al.   MOLECULAR NUTRITION & FOOD RESEARCH

AMPK activation enhances PPARα activity to inhibit cardiac hypertrophy via ERK1/2 MAPK signaling pathway

(2011) Rongsen Meng et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment

(2011) B Taylor-Harding et al.   BRITISH JOURNAL OF CANCER

AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure

(2011) C. Beauloye et al.   CARDIOVASCULAR RESEARCH

Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1–Smad signalling

(2011) Ling Yan et al.   CARDIOVASCULAR RESEARCH

In search of new therapeutic targets and strategies for heart failure: recent advances in basic science

(2011) Ajay M Shah et al.   LANCET

Antiobesity activities of indole-3-carbinol in high-fat-diet–induced obese mice

(2011) Hsiao-Pei Chang et al.   NUTRITION

Activating Transcription Factor 3 Deficiency Promotes Cardiac Hypertrophy, Dysfunction, and Fibrosis Induced by Pressure Overload

(2011) Heng Zhou et al.   PLoS One

AMPK in cardiovascular health and disease

(2010) Najeeb A Shirwany et al.   ACTA PHARMACOLOGICA SINICA

Extracellular signal-regulated kinase 1/2 (ERK1/2) signaling in cardiac hypertrophy

(2010) Izhak Kehat et al.   Annals of the New York Academy of Sciences

Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart

(2010) E. E. Creemers et al.   CARDIOVASCULAR RESEARCH

AMP-activated protein kinase and its downstream transcriptional pathways

(2010) Carles Cantó et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Indole-3-carbinol inhibits hepatic stellate cells proliferation by blocking NADPH oxidase/reactive oxygen species/p38 MAPK pathway

(2010) Jie Ping et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Novel regulators and drug targets of cardiac hypertrophy

(2010) Piet Finckenberg et al.   JOURNAL OF HYPERTENSION

Pharmacological Exploitation of Indole-3-Carbinol to Develop Potent Antitumor Agents

(2010) J.-R. Weng et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Mitogen-Activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-Breaking Tale

(2010) Beth A. Rose et al.   PHYSIOLOGICAL REVIEWS

Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts

(2008) Jianhai Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Indole-3-carbinol as a chemopreventive and anti-cancer agent

(2008) Jing-Ru Weng et al.   CANCER LETTERS

AMP Activated Protein Kinase-α2 Deficiency Exacerbates Pressure-Overload–Induced Left Ventricular Hypertrophy and Dysfunction in Mice

(2008) Ping Zhang et al.   HYPERTENSION

AMP-activated Protein Kinase Inhibits Transforming Growth Factor-β-induced Smad3-dependent Transcription and Myofibroblast Transdifferentiation

(2008) Rangnath Mishra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tackling heart failure in the twenty-first century

(2008) James O. Mudd et al.   NATURE