Calcium channel blockers and dementia

Recent Updates of N-Type Calcium Channel Blockers with Therapeutic Potential for Neuropathic Pain and Stroke

(2012) Takashi Yamamoto et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Pharmacological prevention and treatment of vascular dementia: Approaches and perspectives

(2012) Andrius Baskys et al.   EXPERIMENTAL GERONTOLOGY

A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats

(2011) Victoria E. Scott et al.   BIOCHEMICAL PHARMACOLOGY

New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugs

(2011) Salvatore Salomone et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes

(2011) M Mezler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug

(2011) P. F. Copenhaver et al.   Disease Models & Mechanisms

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(2011) Daniel Paris et al.   MOLECULAR MEDICINE

Effects of amyloid-β peptides on voltage-gated L-type CaV1.2 and CaV1.3 Ca2+ channels

(2011) Sunoh Kim et al.   MOLECULES AND CELLS

Is Alzheimer's Disease a Result of Presynaptic Failure? - Synaptic Dysfunctions Induced by Oligomeric β-Amyloid

(2011) Volker Nimmrich et al.   REVIEWS IN THE NEUROSCIENCES

Calcium dysregulation in amyotrophic lateral sclerosis

(2010) Julian Grosskreutz et al.   CELL CALCIUM

The dysregulation of intracellular calcium in Alzheimer disease

(2010) Charlene Supnet et al.   CELL CALCIUM

Rapid Communication: Ca2+ Channel Blockers Attenuate β-Amyloid Peptide Toxicity to Cortical Neurons in Culture

(2010) John H. Weiss et al.   JOURNAL OF NEUROCHEMISTRY

Analgesic Effects of a Substituted N-Triazole Oxindole (TROX-1), a State-Dependent, Voltage-Gated Calcium Channel 2 Blocker

(2010) C. Abbadie et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease

(2010) Thimmappa S. Anekonda et al.   NEUROBIOLOGY OF DISEASE

Calpain inhibition prevents amyloid-β-induced neurodegeneration and associated behavioral dysfunction in rats

(2010) Ivica Granic et al.   NEUROPHARMACOLOGY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Contribution of Vascular Risk Factors to the Progression in Alzheimer Disease

(2009) Elizabeth P. Helzner et al.   ARCHIVES OF NEUROLOGY

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Glutamate, excitotoxicity, and programmed cell death in parkinson disease

(2009) W. Michael Caudle et al.   EXPERIMENTAL NEUROLOGY

Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses

(2009) Efrat Abramov et al.   NATURE NEUROSCIENCE

Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities

(2009) Jin-Tai Yu et al.   PROGRESS IN NEUROBIOLOGY

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

Nimodipine and Its Use in Cerebrovascular Disease: Evidence from Recent Preclinical and Controlled Clinical Studies

(2008) Daniele Tomassoni et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Amyloid   Oligomers (A 1-42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents

(2008) V. Nimmrich et al.   JOURNAL OF NEUROSCIENCE

Aβ-globulomers are formed independently of the fibril pathway

(2008) Gerald P. Gellermann et al.   NEUROBIOLOGY OF DISEASE

Use of calcium antagonists and cognitive decline in old age

(2006) Stella Trompet et al.   NEUROBIOLOGY OF AGING