Lenti-GDNF Gene Therapy Protects Against Alzheimer's Disease-Like Neuropathology in 3xTg-AD Mice and MC65 Cells

Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain

(2014) Susana Revilla et al.   NEUROPHARMACOLOGY

Effects of exercise on mitochondrial function, neuroplasticity and anxio-depressive behavior of mice

(2014) A.S. Aguiar et al.   NEUROSCIENCE

Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms

(2014) Yoelvis García-Mesa et al.   PSYCHONEUROENDOCRINOLOGY

Various roles of astrocytes during recovery from repeated exposure to different doses of lipopolysaccharide

(2013) Yanqing Bian et al.   BEHAVIOURAL BRAIN RESEARCH

Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice

(2013) Nan Lin et al.   BEHAVIOURAL BRAIN RESEARCH

GDNF facilitates differentiation of the adult dentate gyrus-derived neural precursor cells into astrocytes via STAT3

(2013) Shuken Boku et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Potential Neuroprotection Mechanism of GDNF in the 6-OHDA-Induced Cellular Models of Parkinson’s Disease

(2013) Feng Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Upregulation of Glutamate-Aspartate Transporter by Glial Cell Line-Derived Neurotrophic Factor Ameliorates Cell Apoptosis in Neural Retina in Streptozotocin-Induced Diabetic Rats

(2013) Lu Wang et al.   CNS Neuroscience & Therapeutics

The Disturbance of Hippocampal CaMKII/PKA/PKC Phosphorylation in Early Experimental Diabetes Mellitus

(2013) Mei-Hua Liao et al.   CNS Neuroscience & Therapeutics

Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease

(2013) Dong-Mei Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glial cell-line derived neurotrophic factor (GDNF) replacement attenuates motor impairments and nigrostriatal dopamine deficits in 12-month-old mice with a partial deletion of GDNF

(2013) Ofelia M. Littrell et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Upregulation of Glutathione Peroxidase-1 Expression and Activity by Glial Cell Line–Derived Neurotrophic Factor Promotes High-Level Protection of PC12 Cells Against 6-Hydroxydopamine and Hydrogen Peroxide Toxicities

(2013) Ehsan Gharib et al.   REJUVENATION RESEARCH

Ageing of enteric neurons: oxidative stress, neurotrophic factors and antioxidant enzymes

(2012) Kris Korsak et al.   Chemistry Central Journal

Resveratrol promotes neurotrophic factor release from astroglia

(2012) Feng Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Neuroprotection by GDNF in the ischemic brain

(2012) Emília P. Duarte et al.   GROWTH FACTORS

A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons

(2012) D. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Lipopolysaccharide-induced nigral inflammation leads to increased IL-1β tissue content and expression of astrocytic glial cell line-derived neurotrophic factor

(2012) Mahmoud M. Iravani et al.   NEUROSCIENCE LETTERS

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug

(2011) P. F. Copenhaver et al.   Disease Models & Mechanisms

Identification of Novel GDNF Isoforms andcis-Antisense GDNFOS Gene and Their Regulation in Human Middle Temporal Gyrus of Alzheimer Disease

(2011) Mikko Airavaara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optimized Quantities of GDNF Overexpressed by Engineered Astrocytes Are Critical for Protection of Neuroblastoma Cells Against 6-OHDA Toxicity

(2011) Roya Safi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons

(2011) C. Peng et al.   JOURNAL OF NEUROSCIENCE

BDNF-, IGF-1- and GDNF-Secreting Human Neural Progenitor Cells Rescue Amyloid β-Induced Toxicity in Cultured Rat Septal Neurons

(2011) Narisorn Kitiyanant et al.   NEUROCHEMICAL RESEARCH

Macrophage-mediated GDNF Delivery Protects Against Dopaminergic Neurodegeneration: A Therapeutic Strategy for Parkinson's Disease

(2010) KC Biju et al.   MOLECULAR THERAPY

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

(2009) Robert H Kutner et al.   Nature Protocols

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation

(2009) Hung-Ming Wu et al.   NEUROPSYCHOPHARMACOLOGY

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

(2008) Hyun-Seok Hong et al.   NEUROBIOLOGY OF AGING

Astrocyte-secreted GDNF and glutathione antioxidant system protect neurons against 6OHDA cytotoxicity

(2008) Jagdeep K. Sandhu et al.   NEUROBIOLOGY OF DISEASE

Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

(2008) José J. Rodríguez et al.   PLoS One

Expression of GDNF transgene in astrocytes improves cognitive deficits in aged rats

(2007) M. Pertusa et al.   NEUROBIOLOGY OF AGING