Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

(2010) Costantino Iadecola   ACTA NEUROPATHOLOGICA

The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core

(2010) William J. Jagust et al.   Alzheimers & Dementia

Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease

(2010) Xiangling Yin et al.   AMERICAN JOURNAL OF PATHOLOGY

Pharmacological modulation of vascular inflammation in atherothrombosis

(2010) Raffaele De Caterina et al.   Annals of the New York Academy of Sciences

Inflammation and Alzheimer’s disease

(2010) Young-Jung Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

The vascular contribution to Alzheimer's disease

(2010) Robin Altman et al.   CLINICAL SCIENCE

Antiangiogenic mechanisms of simvastatin in retinal endothelial cells

(2010) Yasuaki Hata et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β-peptide elimination from the brain

(2010) Berislav V. Zlokovic et al.   JOURNAL OF NEUROCHEMISTRY

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

(2010) Daniel C Lee et al.   Journal of Neuroinflammation

The Blood-Brain Barrier: Geriatric Relevance of a Critical Brain-Body Interface

(2010) Neer Zeevi et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

The Vascular Hypothesis of Alzheimer’s Disease: Bench to Bedside and Beyond

(2010) Jack C. de la Torre   Neurodegenerative Diseases

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Vascular basis for brain degeneration: faltering controls and risk factors for dementia

(2010) Raj N Kalaria   NUTRITION REVIEWS

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

Contribution of Vascular Risk Factors to the Progression in Alzheimer Disease

(2009) Elizabeth P. Helzner et al.   ARCHIVES OF NEUROLOGY

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease

(2009) Nicholas H. Varvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Amyloid   Interaction with Receptor for Advanced Glycation End Products Up-Regulates Brain Endothelial CCR5 Expression and Promotes T Cells Crossing the Blood-Brain Barrier

(2009) M. Li et al.   JOURNAL OF IMMUNOLOGY

Inflammation in Atherosclerosis

(2009) Peter Libby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

VEGF genetic variability is associated with increased risk of developing Alzheimer's disease

(2009) Roberto Del Bo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

(2009) Vanja Vukic et al.   NEUROBIOLOGY OF DISEASE

Alzheimer’s disease and endothelial dysfunction

(2009) Giuseppe Bomboi et al.   NEUROLOGICAL SCIENCES

Mechanisms of Endothelial Dysfunction, Injury, and Death

(2008) Jordan S. Pober et al.   Annual Review of Pathology-Mechanisms of Disease

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

(2008) Linda A. Kotilinek et al.   BRAIN

Activation of protease-activated receptor1 mediates induction of matrix metalloproteinase-9 by thrombin in rat primary astrocytes

(2008) Min Sik Choi et al.   BRAIN RESEARCH BULLETIN

JAK2-STAT3 signaling pathway mediates thrombin-induced proinflammatory actions of microglia in vitro☆

(2008) C HUANG et al.   JOURNAL OF NEUROIMMUNOLOGY

Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: Role of neuronal NADPH oxidase

(2008) Keun W. Park et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia

(2008) G. Zuliani et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neurovascular signalling defects in neurodegeneration

(2008) Serena Zacchigna et al.   NATURE REVIEWS NEUROSCIENCE

Protective effects of NSAIDs on the development of Alzheimer disease

(2008) Steven C. Vlad et al.   NEUROLOGY

Cyclin C and cyclin dependent kinases 1, 2 and 3 in thrombin-induced neuronal cell cycle progression and apoptosis

(2008) Haripriya Vittal Rao et al.   NEUROSCIENCE LETTERS

Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease

(2008) E. P. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunctional Cell-Cell Signaling in the Neurovascular Unit as a Paradigm for Central Nervous System Disease

(2008) S. Guo et al.   STROKE

Thrombin-induced microglial activation contributes to the degeneration of nigral dopaminergic neurons in vivo

(2008) Cheng-Fang Huang et al.   Neuroscience Bulletin

Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-α in an animal model of inflamed Alzheimer’s disease brain

(2007) Jae K. Ryu et al.   NEUROBIOLOGY OF DISEASE