A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: implications for early detection and therapy

(2011) Vincent T. Marchesi   FASEB JOURNAL

Peripheral reduction of β-amyloid is sufficient to reduce brain β-amyloid: Implications for Alzheimer's disease

(2011) J. Gregor Sutcliffe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Vascular risk factor detection and control may prevent Alzheimer's disease

(2010) Jack C. de la Torre   AGEING RESEARCH REVIEWS

The RAGE Axis

(2010) Shi Fang Yan et al.   CIRCULATION RESEARCH

The 1.5 Å Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding

(2010) HaJeung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

(2010) Michela Guglielmotto et al.   NEUROBIOLOGY OF AGING

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Peripherally Applied A -Containing Inoculates Induce Cerebral  -Amyloidosis

(2010) Y. S. Eisele et al.   SCIENCE

Structural Basis for Ligand Recognition and Activation of RAGE

(2010) Michael Koch et al.   STRUCTURE

Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene

(2009) Anastasia Z. Kalea et al.   FASEB JOURNAL

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-  and neuronal dysfunction

(2009) K. Takuma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

(2008) Michelle C. Janelsins et al.   AMERICAN JOURNAL OF PATHOLOGY

Site-Specific Blockade of RAGE-Vd Prevents Amyloid-  Oligomer Neurotoxicity

(2008) E. Sturchler et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE

SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

(2008) Robert D. Bell et al.   NATURE CELL BIOLOGY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON