Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer’s disease

A patient-level data meta-analysis of standard-of-care treatments from eight prostate cancer clinical trials

(2016) N. Geifman et al.   Scientific Data

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

A survey of current trends in computational drug repositioning

(2015) Jiao Li et al.   BRIEFINGS IN BIOINFORMATICS

Fitting Linear Mixed-Effects Models Usinglme4

(2015) Douglas Bates et al.   Journal of Statistical Software

Statins, cognition, and dementia—systematic review and methodological commentary

(2015) Melinda C. Power et al.   Nature Reviews Neurology

Differences in Alzheimer disease clinical trial outcomes based on age of the participants

(2015) L. S. Schneider et al.   NEUROLOGY

HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer’s disease in a three cohorts study

(2014) V Leduc et al.   MOLECULAR PSYCHIATRY

ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

(2014) Takahisa Kanekiyo et al.   NEURON

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Effect of APOE genotype status on targeted clinical trials outcomes and efficiency in dementia and mild cognitive impairment resulting from Alzheimer's disease

(2013) Richard E. Kennedy et al.   Alzheimers & Dementia

Overview and Findings from the Religious Orders Study

(2013) David A. Bennett et al.   Current Alzheimer Research

Overview and Findings from the Rush Memory and Aging Project

(2013) David A. Bennett et al.   Current Alzheimer Research

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Statins, Bcl-2, and Apoptosis: Cell Death or Cell Protection?

(2013) W. Gibson Wood et al.   MOLECULAR NEUROBIOLOGY

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

(2013) R. Tarawneh et al.   Cold Spring Harbor Perspectives in Medicine

Preventing Alzheimer's Disease

(2012) D. J. Selkoe   SCIENCE

Promise of personalized omics to precision medicine

(2012) Rui Chen et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Chronic Divalproex Sodium to Attenuate Agitation and Clinical Progression of Alzheimer Disease

(2011) Pierre N. Tariot   ARCHIVES OF GENERAL PSYCHIATRY

Statins, Risk of Dementia, and Cognitive Function: Secondary Analysis of the Ginkgo Evaluation of Memory Study

(2011) Kerstin Bettermann et al.   Journal of Stroke & Cerebrovascular Diseases

Linking lipids to Alzheimer's disease: cholesterol and beyond

(2011) Gilbert Di Paolo et al.   NATURE REVIEWS NEUROSCIENCE

A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

(2011) M. Sano et al.   NEUROLOGY

A phase II trial of huperzine A in mild to moderate Alzheimer disease

(2011) M. S. Rafii et al.   NEUROLOGY

Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease

(2010) Joseph F. Quinn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lipid-Lowering Treatment Is Related to Decreased Risk of Dementia: A Population-Based Study (FINRISK)

(2010) A. Solomon et al.   Neurodegenerative Diseases

Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

(2010) H. H. Feldman et al.   NEUROLOGY

Current Alzheimer's disease clinical trials: Methods and placebo outcomes

(2009) Lon S. Schneider et al.   Alzheimers & Dementia

MMRM vs. LOCF: A Comprehensive Comparison Based on Simulation Study and 25 NDA Datasets

(2009) Ohidul Siddiqui et al.   Journal of Biopharmaceutical Statistics

Pravastatin and cognitive function in the elderly. Results of the PROSPER study

(2009) Stella Trompet et al.   JOURNAL OF NEUROLOGY

Alzheimer's Disease Neuroimaging Initiative (ADNI): Clinical characterization

(2009) R. C. Petersen et al.   NEUROLOGY

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

(2008) Paul S. Aisen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study

(2008) M D M Haag et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Statins, incident Alzheimer disease, change in cognitive function, and neuropathology

(2008) Z. Arvanitakis et al.   NEUROLOGY