Improvements in Gene Editing Technology Boost Its Applications in Livestock
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Title
Improvements in Gene Editing Technology Boost Its Applications in Livestock
Authors
Keywords
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Journal
Frontiers in Genetics
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-01-09
DOI
10.3389/fgene.2020.614688
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Note: Only part of the references are listed.- CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs
- (2020) Jiahuan Chen et al. HAEMATOLOGICA
- Prime Editing: Precision Genome Editing by Reverse Transcription
- (2020) Jun Yan et al. MOLECULAR CELL
- CRISPR in livestock: From editing to printing
- (2020) A. Menchaca et al. THERIOGENOLOGY
- Current progress of genome editing in livestock
- (2020) Kiho Lee et al. THERIOGENOLOGY
- Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs
- (2020) Ruiqiang Li et al. TRANSGENIC RESEARCH
- Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
- (2020) Michelle F. Richter et al. NATURE BIOTECHNOLOGY
- Redesigning small ruminant genomes with CRISPR toolkit: Overview and perspectives
- (2020) Peter Kalds et al. THERIOGENOLOGY
- The CRISPR/Cas9 induces large genomic fragment deletions of MSTN and phenotypic changes in sheep
- (2020) Yi DING et al. Journal of Integrative Agriculture
- Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?
- (2020) Nadja Bischoff et al. Cells
- Efficient generation of mouse models with the prime editing system
- (2020) Yao Liu et al. Cell Discovery
- CRISPR/Cas9-Mediated Biallelic Knockout of IRX3 Reduces the Production and Survival of Somatic Cell-Cloned Bama Minipigs
- (2020) Xiangxing Zhu et al. Animals
- Livestock Gene Editing by One-step Embryo Manipulation
- (2020) Sergio Navarro-Serna et al. JOURNAL OF EQUINE VETERINARY SCIENCE
- Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
- (2020) Andrew V. Anzalone et al. NATURE BIOTECHNOLOGY
- CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
- (2020) Ibrahim C. Kurt et al. NATURE BIOTECHNOLOGY
- CRISPR/Cas12a mediated knock-in of the Polled Celtic variant to produce a polled genotype in dairy cattle
- (2020) Felix Schuster et al. Scientific Reports
- Efficient generation of GGTA1-deficient pigs by electroporation of the CRISPR/Cas9 system into in vitro-fertilized zygotes
- (2020) Fuminori Tanihara et al. BMC BIOTECHNOLOGY
- IL2RG ‐deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma‐derived tumours
- (2020) Jilong Ren et al. CELL PROLIFERATION
- Donor-derived spermatogenesis following stem cell transplantation in sterile NANOS2 knockout males
- (2020) Michela Ciccarelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs
- (2020) Matthew A. Coelho et al. Nature Communications
- CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance
- (2020) Kui Xu et al. eLife
- Lack of airway submucosal glands impairs respiratory host defenses
- (2020) Lynda S Ostedgaard et al. eLife
- Generation of Marker-Free pbd-2 Knock-in Pigs Using the CRISPR/Cas9 and Cre/loxP Systems
- (2020) Jing Huang et al. Genes
- Disabling of nephrogenesis in porcine embryos via CRISPR/Cas9-mediated SIX1 and SIX4 gene targeting
- (2019) Junzheng Wang et al. XENOTRANSPLANTATION
- Programmable Base Editing of the Sheep Genome Revealed No Genome-Wide Off-Target Mutations
- (2019) Shiwei Zhou et al. Frontiers in Genetics
- Unlocking HDR-mediated nucleotide editing by identifying high-efficiency target sites using machine learning
- (2019) Aidan R. O’Brien et al. Scientific Reports
- Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
- (2019) Dmitry Kostyushev et al. Scientific Reports
- Simplified pipelines for genetic engineering of mammalian embryos by CRISPR-Cas9 electroporation†
- (2019) Deqiang Miao et al. BIOLOGY OF REPRODUCTION
- Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos
- (2019) Kayla Carey et al. BMC BIOTECHNOLOGY
- Possible detrimental effects of beta‐2‐microglobulin knockout in pigs
- (2019) Hendrik Johannes Sake et al. XENOTRANSPLANTATION
- Generation of cattle knockout for galactose‐α1,3‐galactose and N‐glycolylneuraminic acid antigens
- (2019) Andrea Perota et al. XENOTRANSPLANTATION
- Base pair editing in goat: nonsense codon introgression into FGF 5 results in longer hair
- (2019) Guanwei Li et al. FEBS Journal
- Lessening of porcine epidemic diarrhoea virus susceptibility in piglets after editing of the CMP-N-glycolylneuraminic acid hydroxylase gene with CRISPR/Cas9 to nullify N-glycolylneuraminic acid expression
- (2019) Ching-Fu Tu et al. PLoS One
- Efficient base editing for multiple genes and loci in pigs using base editors
- (2019) Jingke Xie et al. Nature Communications
- CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease)
- (2019) S. L. Eaton et al. Scientific Reports
- Generation of pigs with a Belgian Blue mutation in MSTN using CRISPR/Cpf1-assisted ssODN-mediated homologous recombination
- (2019) Yun-long ZOU et al. Journal of Integrative Agriculture
- Genome-Editing Technologies: Concept, Pros, and Cons of Various Genome-Editing Techniques and Bioethical Concerns for Clinical Application
- (2019) Sikandar Hayat Khan Molecular Therapy-Nucleic Acids
- Farm animals are important biomedical models
- (2019) Debora L Hamernik Animal Frontiers
- Generation of CD163-edited pig via electroporation of the CRISPR/Cas9 system into porcine in vitro-fertilized zygotes
- (2019) Fuminori Tanihara et al. ANIMAL BIOTECHNOLOGY
- CRISPR DNA base editors with reduced RNA off-target and self-editing activities
- (2019) Julian Grünewald et al. NATURE BIOTECHNOLOGY
- Adenine base editors catalyze cytosine conversions in human cells
- (2019) Heon Seok Kim et al. NATURE BIOTECHNOLOGY
- Sheep and Goat Genome Engineering: From Random Transgenesis to the CRISPR Era
- (2019) Peter Kalds et al. Frontiers in Genetics
- CRISPR off-targets: a question of context
- (2019) Maximilian Haeussler CELL BIOLOGY AND TOXICOLOGY
- Targeted knock-in into the OVA locus of chicken cells using CRISPR/Cas9 system with homology-independent targeted integration
- (2019) Ming Shi et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Prostaglandin‐endoperoxide synthase 2 is not required for preimplantation ovine conceptus development in sheep
- (2019) Eleanore V. O'Neil et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system
- (2019) Xiaodong Zou et al. Cell Death & Disease
- Strategies to reduce genetic mosaicism following CRISPR-mediated genome edition in bovine embryos
- (2019) I. Lamas-Toranzo et al. Scientific Reports
- Generation of pRSAD2 gene knock-in pig via CRISPR/Cas9 technology
- (2019) Zicong Xie et al. ANTIVIRAL RESEARCH
- Recent advances in CRISPR/Cas9-mediated knock-ins in mammalian cells
- (2019) Mehdi Banan JOURNAL OF BIOTECHNOLOGY
- Advances in genome editing through control of DNA repair pathways
- (2019) Charles D. Yeh et al. NATURE CELL BIOLOGY
- An efficient gene knock-in strategy using 5′-modified double-stranded DNA donors with short homology arms
- (2019) Yi Yu et al. Nature Chemical Biology
- The use of cells from ANPEP knockout pigs to evaluate the role of aminopeptidase N (APN) as a receptor for porcine deltacoronavirus (PDCoV)
- (2019) Ana Stoian et al. VIROLOGY
- CRISPR/Cas9-Mediated Integration of Large Transgene into Pig CEP112 Locus
- (2019) Guoling Li et al. G3-Genes Genomes Genetics
- Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAH
- (2018) Runjie Zhang et al. Acta Biomaterialia
- CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus
- (2018) Huaqiang Yang et al. ANTIVIRAL RESEARCH
- An FBXO40 knockout generated by CRISPR/Cas9 causes muscle hypertrophy in pigs without detectable pathological effects
- (2018) Yunlong Zou et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease
- (2018) Sen Yan et al. CELL
- A beginner's guide to gene editing
- (2018) Patrick T. Harrison et al. EXPERIMENTAL PHYSIOLOGY
- CRISPR/Cas9-mediated specific integration of fat-1 at the goat MSTN locus
- (2018) Ju Zhang et al. FEBS Journal
- Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing
- (2018) Fei Hao et al. International Journal of Biological Sciences
- Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells
- (2018) Akiko Seki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
- (2018) Luke W Koblan et al. NATURE BIOTECHNOLOGY
- Optimized base editors enable efficient editing in cells, organoids and mice
- (2018) Maria Paz Zafra et al. NATURE BIOTECHNOLOGY
- DNA mismatch repair and oligonucleotide end-protection promote base-pair substitution distal from a CRISPR/Cas9-induced DNA break
- (2018) Tim Harmsen et al. NUCLEIC ACIDS RESEARCH
- Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts
- (2018) Yanina Soledad Bogliotti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of gene-edited sheep with a defined Booroola fecundity gene (FecBB) mutation in bone morphogenetic protein receptor type 1B (BMPR1B) via clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) 9
- (2018) Shiwei Zhou et al. REPRODUCTION FERTILITY AND DEVELOPMENT
- Efficient generation of goats with defined point mutation (I397V) in GDF9 through CRISPR/Cas9
- (2018) Yiyuan Niu et al. REPRODUCTION FERTILITY AND DEVELOPMENT
- Generation of insulin-deficient piglets by disrupting INS gene using CRISPR/Cas9 system
- (2018) Bumrae Cho et al. TRANSGENIC RESEARCH
- Xenotransplantation: back to the future?
- (2018) Raphael P. H. Meier et al. TRANSPLANT INTERNATIONAL
- The CRISPR tool kit for genome editing and beyond
- (2018) Mazhar Adli Nature Communications
- VX-984 is a selective inhibitor of non-homologous end joining, with possible preferential activity in transformed cells
- (2018) Atif J. Khan et al. Oncotarget
- The production of UL16-binding protein 1 targeted pigs using CRISPR technology
- (2018) Zeyland Joanna et al. 3 Biotech
- The production of UL16-binding protein 1 targeted pigs using CRISPR technology
- (2018) Zeyland Joanna et al. 3 Biotech
- Using CRISPR/Cas9 Technology Efficiently targeted of Goat Myostatin through Zygotes Microinjection result in double-muscled phenotype in goats
- (2018) Zhengyi He et al. BIOSCIENCE REPORTS
- Editing porcine IGF2 regulatory element improved meat production in Chinese Bama pigs
- (2018) Guanghai Xiang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- CRISPR/Cas9-mediated sheep MSTN gene knockout and promote sSMSCs differentiation
- (2018) Yani Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Infection dynamics of hepatitis E virus in wild-type and immunoglobulin heavy chain knockout JH (-/-) gnotobiotic piglets
- (2018) Danielle M. Yugo et al. JOURNAL OF VIROLOGY
- Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
- (2018) Johnny H. Hu et al. NATURE
- Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation
- (2018) Fuminori Tanihara et al. PLoS One
- Production of hypoallergenic milk from DNA-free beta-lactoglobulin (BLG) gene knockout cow using zinc-finger nucleases mRNA
- (2018) Zhaolin Sun et al. Scientific Reports
- Mosaicism in CRISPR/Cas9-mediated genome editing
- (2018) Maryam Mehravar et al. DEVELOPMENTAL BIOLOGY
- Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs
- (2018) Bin Fang et al. Disease Models & Mechanisms
- Base editing: precision chemistry on the genome and transcriptome of living cells
- (2018) Holly A. Rees et al. NATURE REVIEWS GENETICS
- Harnessing genomic information for livestock improvement
- (2018) Michel Georges et al. NATURE REVIEWS GENETICS
- Resistance to coronavirus infection in amino peptidase N-deficient pigs
- (2018) Kristin M. Whitworth et al. TRANSGENIC RESEARCH
- Genetic engineering a large animal model of human hypophosphatasia in sheep
- (2018) Diarra K. Williams et al. Scientific Reports
- Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9
- (2018) Peter J. Cowan et al. Current Opinion in Organ Transplantation
- CRISPR/Cas9-mediated loss of FGF5 function increases wool staple length in sheep
- (2017) Wen-Rong Li et al. FEBS Journal
- Mechanisms of precise genome editing using oligonucleotide donors
- (2017) Yinan Kan et al. GENOME RESEARCH
- Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis
- (2017) Tang Hai et al. HUMAN GENETICS
- RAPID COMMUNICATION: Generation of FGF5 knockout sheep via the CRISPR/Cas9 system12
- (2017) R. Hu et al. JOURNAL OF ANIMAL SCIENCE
- Nonhomologous DNA end-joining for repair of DNA double-strand breaks
- (2017) Nicholas R. Pannunzio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vivo genome editing via the HITI method as a tool for gene therapy
- (2017) Keiichiro Suzuki et al. JOURNAL OF HUMAN GENETICS
- Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning
- (2017) Hanchao GAO et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- Genome editing via delivery of Cas9 ribonucleoprotein
- (2017) Mark A. DeWitt et al. METHODS
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
- (2017) Y Bill Kim et al. NATURE BIOTECHNOLOGY
- Highly efficient RNA-guided base editing in mouse embryos
- (2017) Kyoungmi Kim et al. NATURE BIOTECHNOLOGY
- Mapping the genomic landscape of CRISPR–Cas9 cleavage
- (2017) Peter Cameron et al. NATURE METHODS
- Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks
- (2017) Alexandre Paix et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reconstitution ofUCP1using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity
- (2017) Qiantao Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9
- (2017) Dong Niu et al. SCIENCE
- CRISPR/Cas9-mediated knockout of myostatin in Chinese indigenous Erhualian pigs
- (2017) Kankan Wang et al. TRANSGENIC RESEARCH
- CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels
- (2017) Lei Huang et al. Oncotarget
- Correction of a Disease Mutation using CRISPR/Cas9-assisted Genome Editing in Japanese Black Cattle
- (2017) Mitsumi Ikeda et al. Scientific Reports
- Targeted insertion of an anti-CD2 monoclonal antibody transgene into the GGTA1 locus in pigs using FokI-dCas9
- (2017) Mark B. Nottle et al. Scientific Reports
- CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep
- (2017) Marcela Vilarino et al. Scientific Reports
- Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity
- (2017) Alexis C. Komor et al. Science Advances
- CRISPR/Cas9 – Mediated Precise Targeted Integration In Vivo Using a Double Cut Donor with Short Homology Arms
- (2017) Xuan Yao et al. EBioMedicine
- Generation of beta-lactoglobulin knock-out goats using CRISPR/Cas9
- (2017) Wenjun Zhou et al. PLoS One
- Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities—an analysis of CRISPR genome-edited mouse embryos
- (2017) Akihiro Yasue et al. Scientific Reports
- Generation of GGTA1 Mutant Pigs by Direct Pronuclear Microinjection of CRISPR/Cas9 Plasmid Vectors
- (2016) Chin-Kai Chuang et al. ANIMAL BIOTECHNOLOGY
- Biallelicβ-carotene oxygenase 2knockout results in yellow fat in sheep via CRISPR/Cas9
- (2016) Y. Niu et al. ANIMAL GENETICS
- Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ
- (2016) Tomomi Aida et al. BMC GENOMICS
- Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse
- (2016) Masakazu Hashimoto et al. DEVELOPMENTAL BIOLOGY
- Recent Progress in CRISPR/Cas9 Technology
- (2016) Yue Mei et al. Journal of Genetics and Genomics
- Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives
- (2016) Fabian Oceguera-Yanez et al. METHODS
- Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity
- (2016) Josh Tycko et al. MOLECULAR CELL
- In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration
- (2016) Keiichiro Suzuki et al. NATURE
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering
- (2016) Sisi Lai et al. PLoS One
- Livestock in biomedical research: history, current status and future prospective
- (2016) Irina A. Polejaeva et al. REPRODUCTION FERTILITY AND DEVELOPMENT
- Generation ofRUNX3knockout pigs using CRISPR/Cas9-mediated gene targeting
- (2016) J-T Kang et al. REPRODUCTION IN DOMESTIC ANIMALS
- Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
- (2016) K. Nishida et al. SCIENCE
- Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
- (2016) F. Jiang et al. SCIENCE
- Zygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs
- (2016) Kristin M. Whitworth et al. TRANSGENIC RESEARCH
- Efficient production of biallelicGGTA1knockout pigsbycytoplasmic microinjection of CRISPR/Cas9 into zygotes
- (2016) Bjoern Petersen et al. XENOTRANSPLANTATION
- ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes
- (2016) Kazuto Yoshimi et al. Nature Communications
- RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
- (2016) Jun Song et al. Nature Communications
- Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency
- (2016) Shaohua Lei et al. Scientific Reports
- Isozygous and selectable marker-free MSTN knockout cloned pigs generated by the combined use of CRISPR/Cas9 and Cre/LoxP
- (2016) Yanzhen Bi et al. Scientific Reports
- Two Distinct Pathways Support Gene Correction by Single-Stranded Donors at DNA Nicks
- (2016) Luther Davis et al. Cell Reports
- Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases
- (2016) Jean-Baptiste Renaud et al. Cell Reports
- Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair
- (2016) Kankan Wang et al. Molecular Therapy-Nucleic Acids
- Mammalian interspecies substitution of immune modulatory alleles by genome editing
- (2016) Simon G. Lillico et al. Scientific Reports
- Efficient production of multi-modified pigs for xenotransplantation by ‘combineering’, gene stacking and gene editing
- (2016) Konrad Fischer et al. Scientific Reports
- Small Molecules Enhance CRISPR Genome Editing in Pluripotent Stem Cells
- (2015) Chen Yu et al. Cell Stem Cell
- Inhibition of nonhomologous end joining to increase the specificity of CRISPR/Cas9 genome editing
- (2015) Supriya V. Vartak et al. FEBS Journal
- Livestock Models in Translational Medicine
- (2015) J. A. Roth et al. ILAR JOURNAL
- Generation of B Cell-Deficient Pigs by Highly Efficient CRISPR/Cas9-Mediated Gene Targeting
- (2015) Fengjiao Chen et al. Journal of Genetics and Genomics
- RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes
- (2015) Sean E Humphrey et al. Journal of Hematology & Oncology
- Engineering large animal models of human disease
- (2015) C Bruce A Whitelaw et al. JOURNAL OF PATHOLOGY
- CRISPR-Cas immunity in prokaryotes
- (2015) Luciano A. Marraffini NATURE
- Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
- (2015) Takeshi Maruyama et al. NATURE BIOTECHNOLOGY
- Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus
- (2015) Kristin M Whitworth et al. NATURE BIOTECHNOLOGY
- Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
- (2015) Ayal Hendel et al. NATURE BIOTECHNOLOGY
- Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
- (2015) Daesik Kim et al. NATURE METHODS
- MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
- (2015) Tetsushi Sakuma et al. Nature Protocols
- Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes
- (2015) M. Crispo et al. PLoS One
- Modeling Disease In Vivo With CRISPR/Cas9
- (2015) Lukas E. Dow TRENDS IN MOLECULAR MEDICINE
- Erratum: Erratum: CRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes
- (2015) Hua Zhong et al. Scientific Reports
- Production of Human Albumin in Pigs Through CRISPR/Cas9-Mediated Knockin of Human cDNA into Swine Albumin Locus in the Zygotes
- (2015) Jin Peng et al. Scientific Reports
- Application of CRISPR/Cas9 for biomedical discoveries
- (2015) Sean M. Riordan et al. Cell and Bioscience
- Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing
- (2015) Francis Robert et al. Genome Medicine
- Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
- (2015) Xiao-Hui Zhang et al. Molecular Therapy-Nucleic Acids
- Efficacy of the porcine species in biomedical research
- (2015) Karina Gutierrez et al. Frontiers in Genetics
- Highly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs
- (2015) Jinxue Ruan et al. Scientific Reports
- Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos1
- (2014) Kristin M. Whitworth et al. BIOLOGY OF REPRODUCTION
- Improving livestock for agriculture - technological progress from random transgenesis to precision genome editing heralds a new era
- (2014) Götz Laible et al. Biotechnology Journal
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- One-step generation of knockout pigs by zygote injection of CRISPR/Cas system
- (2014) Tang Hai et al. CELL RESEARCH
- Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer
- (2014) Xiaoqing Zhou et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
- (2014) S. Kim et al. GENOME RESEARCH
- Creating Class I MHC–Null Pigs Using Guide RNA and the Cas9 Endonuclease
- (2014) Luz M. Reyes et al. JOURNAL OF IMMUNOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Efficient Gene Knockout in Goats Using CRISPR/Cas9 System
- (2014) Wei Ni et al. PLoS One
- Evaluation of sgRNA Target Sites for CRISPR-Mediated Repression of TP53
- (2014) Ingrid E. B. Lawhorn et al. PLoS One
- Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection
- (2014) Ping Li et al. XENOTRANSPLANTATION
- Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases
- (2014) Daniel Sommer et al. Nature Communications
- Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
- (2014) Shota Nakade et al. Nature Communications
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- (2013) S. W. Cho et al. GENOME RESEARCH
- Breaking and joining single-stranded DNA: the HUH endonuclease superfamily
- (2013) Michael Chandler et al. NATURE REVIEWS MICROBIOLOGY
- Efficient nonmeiotic allele introgression in livestock using custom endonucleases
- (2013) W. Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
- (2013) Thomas Gaj et al. TRENDS IN BIOTECHNOLOGY
- TALENs: a widely applicable technology for targeted genome editing
- (2012) J. Keith Joung et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Insights from past millennia into climatic impacts on human health and survival
- (2012) A. J. McMichael PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection
- (2012) Rachel J. Derscheid et al. Viruses-Basel
- Solutions for a cultivated planet
- (2011) Jonathan A. Foley et al. NATURE
- Gene editing: not just for translation anymore
- (2011) Moira A McMahon et al. NATURE METHODS
- Global food demand and the sustainable intensification of agriculture
- (2011) D. Tilman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Airway disease: The use of large animal models for drug discovery
- (2011) Joanne Van der Velden et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Mammalian cell transfection: the present and the future
- (2010) Tae Kyung Kim et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Genome editing with engineered zinc finger nucleases
- (2010) Fyodor D. Urnov et al. NATURE REVIEWS GENETICS
- Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases
- (2010) M. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Food Security: The Challenge of Feeding 9 Billion People
- (2010) H. C. J. Godfray et al. SCIENCE
- A frameshift mutation in the coding region of themyostatingene (MSTN) affects carcass conformation and fatness in Norwegian White Sheep (Ovis aries)
- (2009) I. A. Boman et al. ANIMAL GENETICS
- Commentary on Domestic Animals in Agricultural and Biomedical Research: An Endangered Enterprise
- (2009) Lawrence P. Reynolds et al. JOURNAL OF NUTRITION
- The Prion's Elusive Reason for Being
- (2008) Adriano Aguzzi et al. Annual Review of Neuroscience
- MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings
- (2008) Mitch McVey et al. TRENDS IN GENETICS
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