Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering
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Title
Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering
Authors
Keywords
Blastocysts, Polymerase chain reaction, Fetuses, Embryos, Pig models, Swine, Fibroblasts, Pluripotency
Journal
PLoS One
Volume 11, Issue 1, Pages e0146562
Publisher
Public Library of Science (PLoS)
Online
2016-01-13
DOI
10.1371/journal.pone.0146562
References
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Note: Only part of the references are listed.- CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
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- (2014) Nicole A. J. Krentz et al. PLoS One
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- RNA-Guided Human Genome Engineering via Cas9
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- oct4-EGFP reporter gene expression marks the stem cells in embryonic development and in adult gonads of transgenic medaka
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- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Establishment of a Porcine Oct-4 Promoter-Driven EGFP Reporter System for Monitoring Pluripotency of Porcine Stem Cells
- (2011) Lizhen Huang et al. Cellular Reprogramming
- Role of Oct4 in maintaining and regaining stem cell pluripotency
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- Oct4-Enhanced Green Fluorescent Protein Transgenic Pigs: A New Large Animal Model for Reprogramming Studies
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- Derivation of induced pluripotent stem cells from pig somatic cells
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- Generation of Pig Induced Pluripotent Stem Cells with a Drug-Inducible System
- (2009) Zhao Wu et al. Journal of Molecular Cell Biology
- Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
- (2008) C. S. Rogers et al. SCIENCE
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