Generation of CD163-edited pig via electroporation of the CRISPR/Cas9 system into porcine in vitro-fertilized zygotes

Transboundary spread of pig diseases: the role of international trade and travel

(2019) Daniel Beltran-Alcrudo et al.   BMC Veterinary Research

Simplified pipelines for genetic engineering of mammalian embryos by CRISPR-Cas9 electroporation†

(2019) Deqiang Miao et al.   BIOLOGY OF REPRODUCTION

Aminopeptidase N Knockout Pigs Are Not Resistant to Porcine Epidemic Diarrhea Virus Infection

(2019) Jian Zhang et al.   VIROLOGICA SINICA

CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus

(2018) Huaqiang Yang et al.   ANTIVIRAL RESEARCH

Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation

(2018) Fuminori Tanihara et al.   PLoS One

Generation of PDX-1 mutant porcine blastocysts by introducing CRISPR/Cas9-system into porcine zygotes via electroporation

(2018) Fuminori Tanihara et al.   ANIMAL SCIENCE JOURNAL

Resistance to coronavirus infection in amino peptidase N-deficient pigs

(2018) Kristin M. Whitworth et al.   TRANSGENIC RESEARCH

Genetically edited pigs lacking CD163 show no resistance following infection with the African swine fever virus isolate, Georgia 2007/1

(2017) Luca Popescu et al.   VIROLOGY

Aminopeptidase N is not required for porcine epidemic diarrhea virus cell entry

(2017) Wentao Li et al.   VIRUS RESEARCH

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

(2017) Christine Burkard et al.   PLoS Pathogens

Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)

(2017) Randall S. Prather et al.   Scientific Reports

Porcine aminopeptidase N is not a cellular receptor of porcine epidemic diarrhea virus, but promotes its infectivity via aminopeptidase activity

(2016) Kazuya Shirato et al.   JOURNAL OF GENERAL VIROLOGY

Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus

(2016) Kevin D. Wells et al.   JOURNAL OF VIROLOGY

Somatic cell reprogramming-free generation of genetically modified pigs

(2016) F. Tanihara et al.   Science Advances

Systematic analysis of CRISPR–Cas9 mismatch tolerance reveals low levels of off-target activity

(2015) Emily M. Anderson et al.   JOURNAL OF BIOTECHNOLOGY

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

(2015) Kristin M Whitworth et al.   NATURE BIOTECHNOLOGY

Astaxanthin present in the maturation medium reduces negative effects of heat shock on the developmental competence of porcine oocytes

(2015) Lanh Thi Kim Do et al.   Reproductive Biology

PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity

(2015) Matthew A. Kappes et al.   VIROLOGY

How foot-and-mouth disease virus receptor mediates foot-and-mouth disease virus infection

(2015) Guangxiang Wang et al.   Virology Journal

Impact of Porcine Epidemic Diarrhea on Performance of Growing Pigs

(2015) Julio Alvarez et al.   PLoS One

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites

(2014) Yuki Naito et al.   BIOINFORMATICS

Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos1

(2014) Kristin M. Whitworth et al.   BIOLOGY OF REPRODUCTION

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

(2014) Thomas J Cradick et al.   Molecular Therapy-Nucleic Acids

Genetically Modified Pig Models for Human Diseases

(2013) Nana Fan et al.   Journal of Genetics and Genomics

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

African swine fever: how can global spread be prevented?

(2009) S. Costard et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection

(2009) Eeuri Nam et al.   VETERINARY MICROBIOLOGY