CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep

CRISPR/Cas9-mediated loss of FGF5 function increases wool staple length in sheep

(2017) Wen-Rong Li et al.   FEBS Journal

RAPID COMMUNICATION: Generation of FGF5 knockout sheep via the CRISPR/Cas9 system12

(2017) R. Hu et al.   JOURNAL OF ANIMAL SCIENCE

An AANAT/ASMT transgenic animal model constructed with CRISPR/Cas9 system serving as the mammary gland bioreactor to produce melatonin-enriched milk in sheep

(2017) Teng Ma et al.   JOURNAL OF PINEAL RESEARCH

Correction of a pathogenic gene mutation in human embryos

(2017) Hong Ma et al.   NATURE

Interspecies organogenesis generates autologous functional islets

(2017) Tomoyuki Yamaguchi et al.   NATURE

Alteration of sheep coat color pattern by disruption of ASIP gene via CRISPR Cas9

(2017) Xuemei Zhang et al.   Scientific Reports

CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs

(2017) Jun Wu et al.   Scientific Reports

Biallelicβ-carotene oxygenase 2knockout results in yellow fat in sheep via CRISPR/Cas9

(2016) Y. Niu et al.   ANIMAL GENETICS

Efficient dual sgRNA-directed large gene deletion in rabbit with CRISPR/Cas9 system

(2016) Yuning Song et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

CrispRVariants charts the mutation spectrum of genome engineering experiments

(2016) Helen Lindsay et al.   NATURE BIOTECHNOLOGY

Genetically engineered livestock for agriculture: a generation after the first transgenic animal research conference

(2016) James D. Murray et al.   TRANSGENIC RESEARCH

Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep

(2016) Xiaolong Wang et al.   Scientific Reports

Pluripotent Stem Cells from Domesticated Mammals

(2016) Toshihiko Ezashi et al.   Annual Review of Animal Biosciences

Laser-assisted Cytoplasmic Microinjection in Livestock Zygotes

(2016) Yanina S. Bogliotti et al.   Jove-Journal of Visualized Experiments

Rosa26-targeted sheep gene knock-in via CRISPR-Cas9 system

(2016) Mingming Wu et al.   Scientific Reports

Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

(2015) M. Crispo et al.   PLoS One

Revisiting the Flight of Icarus: Making Human Organs from PSCs with Large Animal Chimeras

(2014) Tamir Rashid et al.   Cell Stem Cell

Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes

(2014) Shuo-Ting Yen et al.   DEVELOPMENTAL BIOLOGY

Dual sgRNAs facilitate CRISPR/Cas9-mediated mouse genome targeting

(2014) Jiankui Zhou et al.   FEBS Journal

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Heritable Multiplex Genetic Engineering in Rats Using CRISPR/Cas9

(2014) Yuanwu Ma et al.   PLoS One

Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

(2013) H. Matsunari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Generation of Kidney from Pluripotent Stem Cells via Blastocyst Complementation

(2012) Jo-ichi Usui et al.   AMERICAN JOURNAL OF PATHOLOGY

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

(2010) Toshihiro Kobayashi et al.   CELL

Pdx1 and other factors that regulate pancreatic β-cell survival

(2009) K. Fujimoto et al.   DIABETES OBESITY & METABOLISM