Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
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Title
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
Authors
Keywords
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Journal
NATURE
Volume 551, Issue 7681, Pages 464-471
Publisher
Springer Nature
Online
2017-10-24
DOI
10.1038/nature24644
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- CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations
- (2017) Cem Kuscu et al. NATURE METHODS
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- (2017) Dylan Kwart et al. Nature Protocols
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- Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity
- (2017) Alexis C. Komor et al. Science Advances
- Precise genome-wide base editing by the CRISPR Nickase system in yeast
- (2017) Atsushi Satomura et al. Scientific Reports
- Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
- (2016) Ahmed H. Badran et al. NATURE
- Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
- (2016) Dominik Paquet et al. NATURE
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition
- (2016) Elizabeth A Traxler et al. NATURE MEDICINE
- Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
- (2016) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity
- (2016) Melissa M Matthews et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cytosine deamination and the precipitous decline of spontaneous mutation during Earth's history
- (2016) Charles A. Lewis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
- (2016) K. Nishida et al. SCIENCE
- Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
- (2016) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity
- (2016) Melissa M Matthews et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ClinVar: public archive of interpretations of clinically relevant variants
- (2015) Melissa J. Landrum et al. NUCLEIC ACIDS RESEARCH
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies
- (2013) Eyal Grunebaum et al. Current Opinion in Allergy and Clinical Immunology
- A system for the continuous directed evolution of biomolecules
- (2011) Kevin M. Esvelt et al. NATURE
- HFE-associated hereditary hemochromatosis
- (2009) Jacob Alexander et al. GENETICS IN MEDICINE
- Miscoding Properties of 2′-Deoxyinosine, a Nitric Oxide-Derived DNA Adduct, during Translesion Synthesis Catalyzed by Human DNA Polymerases
- (2008) Manabu Yasui et al. JOURNAL OF MOLECULAR BIOLOGY
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