Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD
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Title
Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD
Authors
Keywords
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Journal
Frontiers in Neuroscience
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-06-11
DOI
10.3389/fnins.2019.00548
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Note: Only part of the references are listed.- C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A
- (2019) Thomas G. Moens et al. ACTA NEUROPATHOLOGICA
- CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1
- (2019) Judith M. Silverman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multi-omic measurements of heterogeneity in HeLa cells across laboratories
- (2019) Yansheng Liu et al. NATURE BIOTECHNOLOGY
- RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43
- (2019) Elsa Zacco et al. JOURNAL OF MOLECULAR BIOLOGY
- Transcriptome–pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS
- (2018) Florian Krach et al. ACTA NEUROPATHOLOGICA
- Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis
- (2018) Alexander G. Thompson et al. ANNALS OF NEUROLOGY
- TDP43 and RNA instability in amyotrophic lateral sclerosis
- (2018) Kaitlin Weskamp et al. BRAIN RESEARCH
- Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
- (2018) Sebastian Markmiller et al. CELL
- The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis
- (2018) Yingying Zhang et al. GENES & DEVELOPMENT
- TAR DNA-binding protein 43 (TDP-43) liquid–liquid phase separation is mediated by just a few aromatic residues
- (2018) Hao-Ru Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The prion-like domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization
- (2018) Shannon N. Rhoads et al. MOLECULAR BIOLOGY OF THE CELL
- Molecular and functional signatures in a novel Alzheimer’s disease mouse model assessed by quantitative proteomics
- (2018) Dong Kyu Kim et al. Molecular Neurodegeneration
- TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
- (2018) Ching-Chieh Chou et al. NATURE NEUROSCIENCE
- TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics
- (2018) Stephani A. Davis et al. NEUROSCIENCE LETTERS
- RNA buffers the phase separation behavior of prion-like RNA binding proteins
- (2018) Shovamayee Maharana et al. SCIENCE
- ALS Genes in the Genomic Era and their Implications for FTD
- (2018) Hung Phuoc Nguyen et al. TRENDS IN GENETICS
- Abnormal RNA stability in amyotrophic lateral sclerosis
- (2018) E. M. Tank et al. Nature Communications
- Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects
- (2018) Zhouwei Xu et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis
- (2018) Matthew D. Cykowski et al. Acta Neuropathologica Communications
- Motor Neuron Disease: Pathophysiology, Diagnosis, and Management
- (2018) Laura A. Foster et al. AMERICAN JOURNAL OF MEDICINE
- Preliminary Observation about Alteration of Proteins and Their Potential Functions in Spinal Cord of SOD1 G93A Transgenic Mice
- (2018) Jie Zhang et al. International Journal of Biological Sciences
- Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43kDa (TDP-43)
- (2018) Friederike Hans et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity
- (2018) Moushami Mallik et al. JOURNAL OF CELL BIOLOGY
- Deep Dive on the Proteome of Human Cerebrospinal Fluid: A Valuable Data Resource for Biomarker Discovery and Missing Protein Identification
- (2018) Charlotte Macron et al. JOURNAL OF PROTEOME RESEARCH
- Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial
- (2018) Christina Ludwig et al. Molecular Systems Biology
- Efficient proximity labeling in living cells and organisms with TurboID
- (2018) Tess C Branon et al. NATURE BIOTECHNOLOGY
- Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration
- (2018) Sharan Paul et al. Nature Communications
- Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells
- (2018) Edward Pokrishevsky et al. Scientific Reports
- New Antibody-Free Mass Spectrometry-Based Quantification Reveals That C9ORF72 Long Protein Isoform Is Reduced in the Frontal Cortex of Hexanucleotide-Repeat Expansion Carriers
- (2018) Arthur Viodé et al. Frontiers in Neuroscience
- RNA binding proteins co-localize with small tau inclusions in tauopathy
- (2018) Brandon F. Maziuk et al. Acta Neuropathologica Communications
- CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper–Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding
- (2018) Natalie E. Farrawell et al. ACS Chemical Neuroscience
- A Quantitative Chemical Proteomics Approach for Site-specific Stoichiometry Analysis of Ubiquitination
- (2018) Yunan Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
- (2018) Marina Iridoy et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Postnovo: Postprocessing Enables Accurate and FDR-Controlled de Novo Peptide Sequencing
- (2018) Samuel E. Miller et al. JOURNAL OF PROTEOME RESEARCH
- Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis
- (2018) Irene Zubiri et al. Molecular Neurodegeneration
- TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates
- (2018) Florent Laferrière et al. NATURE NEUROSCIENCE
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The BioGRID interaction database: 2019 update
- (2018) Rose Oughtred et al. NUCLEIC ACIDS RESEARCH
- Machine Learning Reveals Protein Signatures in CSF and Plasma Fluids of Clinical Value for ALS
- (2018) Michael S. Bereman et al. Scientific Reports
- Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS
- (2018) Arundhati Sengupta-Ghosh et al. NEUROBIOLOGY OF DISEASE
- Proteomic studies in the discovery of cerebrospinal fluid biomarkers for amyotrophic lateral sclerosis
- (2017) Peggy Barschke et al. Expert Review of Proteomics
- Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype
- (2017) Alison L. Hogan et al. HUMAN MOLECULAR GENETICS
- MALDI versus ESI: The Impact of the Ion Source on Peptide Identification
- (2017) Wiebke Maria Nadler et al. JOURNAL OF PROTEOME RESEARCH
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- The lysosomal protein cathepsin L is a progranulin protease
- (2017) Chris W. Lee et al. Molecular Neurodegeneration
- The heat shock response in neurons and astroglia and its role in neurodegenerative diseases
- (2017) Rebecca San Gil et al. Molecular Neurodegeneration
- Biotinylation by antibody recognition—a method for proximity labeling
- (2017) Daniel Z Bar et al. NATURE METHODS
- Frontotemporal Dementia
- (2017) Nicholas T. Olney et al. NEUROLOGIC CLINICS
- Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice
- (2017) Zoe A. Klein et al. NEURON
- Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS
- (2017) Prajwal Ciryam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of the Tau phosphorylation pattern that drives its aggregation
- (2017) Clément Despres et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum Proteome in a Sporadic Amyotrophic Lateral Sclerosis Geographical Cluster
- (2017) Stefano De Benedetti et al. Proteomics Clinical Applications
- A Golden Age for Working with Public Proteomics Data
- (2017) Lennart Martens et al. TRENDS IN BIOCHEMICAL SCIENCES
- Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program
- (2017) Ping Wang et al. Nature Communications
- Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes
- (2017) Nadine Ait-Bouziad et al. Nature Communications
- 3′UTR Length-Dependent Control of SynGAP Isoform α2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function
- (2017) Satoshi Yokoi et al. Cell Reports
- Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients
- (2017) Shanye Yin et al. Cell Reports
- Tau Oligomers: Cytotoxicity, Propagation, and Mitochondrial Damage
- (2017) Scott S. Shafiei et al. Frontiers in Aging Neuroscience
- Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF (cyclin F) complex
- (2017) Albert Lee et al. Open Biology
- Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106
- (2017) Barbara Celona et al. eLife
- Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?
- (2017) Christopher P. Webster et al. Frontiers in Molecular Neuroscience
- Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis
- (2017) Jee-Eun Kim et al. PLoS One
- Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways
- (2016) Anna M. Blokhuis et al. ACTA NEUROPATHOLOGICA
- Noncovalent Interactions between Superoxide Dismutase and Flavonoids Studied by Native Mass Spectrometry Combined with Molecular Simulations
- (2016) Xiaoyu Zhuang et al. ANALYTICAL CHEMISTRY
- Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS
- (2016) Marisa Kamelgarn et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts
- (2016) Malathi Narayan et al. Biomarkers in Medicine
- Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein–protein interaction network
- (2016) Yang Li et al. BRAIN RESEARCH
- C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
- (2016) Kyung-Ha Lee et al. CELL
- Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
- (2016) Kohsuke Kanekura et al. HUMAN MOLECULAR GENETICS
- Comprehensive Quantitative Profiling of Tau and Phosphorylated Tau Peptides in Cerebrospinal Fluid by Mass Spectrometry Provides New Biomarker Candidates
- (2016) Claire L. Russell et al. JOURNAL OF ALZHEIMERS DISEASE
- Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
- (2016) Chang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Relationship between mutant Cu/Zn superoxide dismutase 1 maturation and inclusion formation in cell models
- (2016) Jacob I. Ayers et al. JOURNAL OF NEUROCHEMISTRY
- Tau physiology and pathomechanisms in frontotemporal lobar degeneration
- (2016) Liviu-Gabriel Bodea et al. JOURNAL OF NEUROCHEMISTRY
- An improved smaller biotin ligase for BioID proximity labeling
- (2016) Dae In Kim et al. MOLECULAR BIOLOGY OF THE CELL
- Ingenuity Pathway Analysis of Gene Expression Profiles in Distal Nerve Stump following Nerve Injury: Insights into Wallerian Degeneration
- (2016) Jun Yu et al. Frontiers in Cellular Neuroscience
- Proteomic analysis of cerebrospinal fluid in amyotrophic lateral sclerosis
- (2016) YAN CHEN et al. Experimental and Therapeutic Medicine
- CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia
- (2016) Kelly L. Williams et al. Nature Communications
- Proteomic profiling of the spinal cord in ALS: decreased ATP5D levels suggest synaptic dysfunction in ALS pathogenesis
- (2016) Jooyeon Engelen-Lee et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Susceptibility of Mutant SOD1 to Form a Destabilized Monomer Predicts Cellular Aggregation and Toxicity but Not In vitro Aggregation Propensity
- (2016) Luke McAlary et al. Frontiers in Neuroscience
- The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway
- (2016) Peter M. Sullivan et al. Acta Neuropathologica Communications
- VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies
- (2016) Carla Brancia et al. PLoS One
- Mass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains
- (2016) Fuyuki Kametani et al. Scientific Reports
- Rapid flow cytometric measurement of protein inclusions and nuclear trafficking
- (2016) D. R. Whiten et al. Scientific Reports
- Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS
- (2015) Céline Ruegsegger et al. ACTA NEUROPATHOLOGICA
- Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau
- (2015) Sayuri Taniguchi-Watanabe et al. ACTA NEUROPATHOLOGICA
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Evidence for Fungal Infection in Cerebrospinal Fluid and Brain Tissue from Patients with Amyotrophic Lateral Sclerosis
- (2015) Ruth Alonso et al. International Journal of Biological Sciences
- Regulation of Postsynaptic Function by the Dementia-Related ESCRT-III Subunit CHMP2B
- (2015) R. Chassefeyre et al. JOURNAL OF NEUROSCIENCE
- Label-Free LC–MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis
- (2015) Mahlon A. Collins et al. JOURNAL OF PROTEOME RESEARCH
- Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1
- (2015) Noga Gershoni-Emek et al. MOLECULAR & CELLULAR PROTEOMICS
- The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome
- (2015) C. Geeth Gunawardana et al. MOLECULAR & CELLULAR PROTEOMICS
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration–associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways
- (2015) Tao Wang et al. NEUROBIOLOGY OF AGING
- Cerebrospinal Fluid from Sporadic Amyotrophic Lateral Sclerosis Patients Induces Mitochondrial and Lysosomal Dysfunction
- (2015) Aparna Sharma et al. NEUROCHEMICAL RESEARCH
- Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport
- (2015) M. Štalekar et al. NEUROSCIENCE
- Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
- (2015) Harindranath Kadavath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Connecting the dots between tau dysfunction and neurodegeneration
- (2015) Bess Frost et al. TRENDS IN CELL BIOLOGY
- Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice
- (2015) Dapeng Chen et al. Frontiers in Cellular Neuroscience
- An acetylation switch controls TDP-43 function and aggregation propensity
- (2015) Todd J. Cohen et al. Nature Communications
- ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP
- (2015) Shuying Sun et al. Nature Communications
- Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins
- (2015) Fabian Hosp et al. Cell Reports
- Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis
- (2014) Paul C. Trippier et al. ACS Chemical Neuroscience
- C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
- (2014) Stephanie May et al. ACTA NEUROPATHOLOGICA
- Bioinformatic analysis of proteomics data
- (2014) Andreas Schmidt et al. BMC Systems Biology
- Dimerization of visinin-like protein 1 is regulated by oxidative stress and calcium and is a pathological hallmark of amyotrophic lateral sclerosis
- (2014) Martina P. Liebl et al. FREE RADICAL BIOLOGY AND MEDICINE
- C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
- (2014) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- Insights into the Role of the Unusual Disulfide Bond in Copper-Zinc Superoxide Dismutase
- (2014) Kevin Sea et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a Misfolded Region in Superoxide Dismutase 1 That Is Exposed in Amyotrophic Lateral Sclerosis
- (2014) Melissa S. Rotunno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
- (2014) E. L. Scotter et al. JOURNAL OF CELL SCIENCE
- Human SOD1-G93A Specific Distribution Evidenced in Murine Brain of a Transgenic Model for Amyotrophic Lateral Sclerosis by MALDI Imaging Mass Spectrometry
- (2014) Elena Acquadro et al. JOURNAL OF PROTEOME RESEARCH
- Alterations in muscle proteome of patients diagnosed with amyotrophic lateral sclerosis
- (2014) Kristin Elf et al. Journal of Proteomics
- In-depth Characterization of the Cerebrospinal Fluid (CSF) Proteome Displayed Through the CSF Proteome Resource (CSF-PR)
- (2014) Astrid Guldbrandsen et al. MOLECULAR & CELLULAR PROTEOMICS
- Directed evolution of APEX2 for electron microscopy and proximity labeling
- (2014) Stephanie S Lam et al. NATURE METHODS
- Proteostasis impairment in protein-misfolding and -aggregation diseases
- (2014) Mark S. Hipp et al. TRENDS IN CELL BIOLOGY
- Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases
- (2014) Emily Feneberg et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- SOD1 oxidation and formation of soluble aggregates in yeast: Relevance to sporadic ALS development
- (2014) Dorival Martins et al. Redox Biology
- Increased expression of Myosin binding protein H in the skeletal muscle of amyotrophic lateral sclerosis patients
- (2013) Antonio Conti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Proteostasis and neurodegeneration: The roles of proteasomal degradation and autophagy
- (2013) Keiji Tanaka et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Comparison of label-free and label-based strategies for proteome analysis of hepatoma cell lines
- (2013) Dominik A. Megger et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
- (2013) Rachele A. Saccon et al. BRAIN
- Accelerated neurodegeneration through chaperone-mediated oligomerization of tau
- (2013) Laura J. Blair et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of Metal Loading and Subcellular pH on Net Charge of Superoxide Dismutase-1
- (2013) Yunhua Shi et al. JOURNAL OF MOLECULAR BIOLOGY
- Sources of Technical Variability in Quantitative LC–MS Proteomics: Human Brain Tissue Sample Analysis
- (2013) Paul D. Piehowski et al. JOURNAL OF PROTEOME RESEARCH
- Angiogenin induces modifications in the astrocyte secretome: Relevance to amyotrophic lateral sclerosis
- (2013) Alexandra Skorupa et al. Journal of Proteomics
- Deamidation of Asparagine to Aspartate Destabilizes Cu, Zn Superoxide Dismutase, Accelerates Fibrillization, and Mirrors ALS-Linked Mutations
- (2013) Yunhua Shi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multiplexed and data-independent tandem mass spectrometry for global proteome profiling
- (2013) John D. Chapman et al. MASS SPECTROMETRY REVIEWS
- Status of Large-scale Analysis of Post-translational Modifications by Mass Spectrometry
- (2013) Jesper V. Olsen et al. MOLECULAR & CELLULAR PROTEOMICS
- Mapping and analysis of phosphorylation sites: a quick guide for cell biologists
- (2013) Noah Dephoure et al. MOLECULAR BIOLOGY OF THE CELL
- Heat shock factor 1 over-expression protects against exposure of hydrophobic residues on mutant SOD1 and early mortality in a mouse model of amyotrophic lateral sclerosis
- (2013) Pei-Yi Lin et al. Molecular Neurodegeneration
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- Plasma Peptide Biomarker Discovery for Amyotrophic Lateral Sclerosis by MALDI –TOF Mass Spectrometry Profiling
- (2013) Laurence Conraux et al. PLoS One
- Proteomic Analysis Reveals Differentially Regulated Protein Acetylation in Human Amyotrophic Lateral Sclerosis Spinal Cord
- (2013) Dong Liu et al. PLoS One
- Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm
- (2013) Y. Song et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy
- (2013) P. K. Chan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging
- (2013) H.-W. Rhee et al. SCIENCE
- A six-plex proteome quantification strategy reveals the dynamics of protein turnover
- (2013) Fangjun Wang et al. Scientific Reports
- Molecular Signatures of Amyotrophic Lateral Sclerosis Disease Progression in Hind and Forelimb Muscles of an SOD1G93A Mouse Model
- (2012) Daniele Capitanio et al. ANTIOXIDANTS & REDOX SIGNALING
- Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
- (2012) Cristian A. Lasagna-Reeves et al. FASEB JOURNAL
- Cell signaling, post-translational protein modifications and NMR spectroscopy
- (2012) Francois-Xavier Theillet et al. JOURNAL OF BIOMOLECULAR NMR
- A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells
- (2012) Kyle J. Roux et al. JOURNAL OF CELL BIOLOGY
- Quantitative Analysis of the Detergent-Insoluble Brain Proteome in Frontotemporal Lobar Degeneration Using SILAC Internal Standards
- (2012) Nicholas T. Seyfried et al. JOURNAL OF PROTEOME RESEARCH
- Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking
- (2012) Dale S. Haines et al. MOLECULAR & CELLULAR PROTEOMICS
- Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis
- (2012) Ludovic C. Gillet et al. MOLECULAR & CELLULAR PROTEOMICS
- Deciphering a global network of functionally associated post-translational modifications
- (2012) Pablo Minguez et al. Molecular Systems Biology
- Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy
- (2012) Jeffrey D Martell et al. NATURE BIOTECHNOLOGY
- Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination
- (2012) Eric B. Dammer et al. PLoS One
- Phosphorylated -Synuclein in Parkinson's Disease
- (2012) Y. Wang et al. Science Translational Medicine
- Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding
- (2012) Sudhakaran Prabakaran et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis
- (2011) Adam K. Walker et al. IUBMB LIFE
- Proteins That Bind to Misfolded Mutant Superoxide Dismutase-1 in Spinal Cords from Transgenic Amyotrophic Lateral Sclerosis (ALS) Model Mice
- (2011) Per Zetterström et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner
- (2011) Anne Gauthier-Kemper et al. JOURNAL OF CELL BIOLOGY
- Universal and Confident Phosphorylation Site Localization Using phosphoRS
- (2011) Thomas Taus et al. JOURNAL OF PROTEOME RESEARCH
- Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome
- (2011) Woong Kim et al. MOLECULAR CELL
- Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration
- (2011) Yair M Gozal et al. Molecular Neurodegeneration
- MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
- (2011) Lily Ting et al. NATURE METHODS
- Amyotrophic Lateral Sclerosis Multiprotein Biomarkers in Peripheral Blood Mononuclear Cells
- (2011) Giovanni Nardo et al. PLoS One
- Progranulin, a Glycoprotein Deficient in Frontotemporal Dementia, Is a Novel Substrate of Several Protein Disulfide Isomerase Family Proteins
- (2011) Sandra Almeida et al. PLoS One
- Less label, more free: Approaches in label-free quantitative mass spectrometry
- (2011) Karlie A. Neilson et al. PROTEOMICS
- Proteomic Analysis of Hippocampal Dentate Granule Cells in Frontotemporal Lobar Degeneration: Application of Laser Capture Technology
- (2011) Yair M. Gozal et al. Frontiers in Neurology
- Carbonic Anhydrase I Is Recognized by an SOD1 Antibody upon Biotinylation of Human Spinal Cord Extracts
- (2010) Jian Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Collapsin Response Mediator Protein 4a (CRMP4a) Is Upregulated in Motoneurons of Mutant SOD1 Mice and Can Trigger Motoneuron Axonal Degeneration and Cell Death
- (2010) L. Duplan et al. JOURNAL OF NEUROSCIENCE
- Galectin-3 Is a Candidate Biomarker for Amyotrophic Lateral Sclerosis: Discovery by a Proteomics Approach
- (2010) Jian-Ying Zhou et al. JOURNAL OF PROTEOME RESEARCH
- Development and application of mass spectrometric methods for the analysis of progranulin N-glycosylation
- (2010) Kriangsak Songsrirote et al. Journal of Proteomics
- Improved Quantitative Mass Spectrometry Methods for Characterizing Complex Ubiquitin Signals
- (2010) Lilian Phu et al. MOLECULAR & CELLULAR PROTEOMICS
- Confident Phosphorylation Site Localization Using the Mascot Delta Score
- (2010) Mikhail M. Savitski et al. MOLECULAR & CELLULAR PROTEOMICS
- Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling
- (2010) Guoqiang Xu et al. NATURE BIOTECHNOLOGY
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
- (2010) Vivianna M Van Deerlin et al. NATURE GENETICS
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
- (2010) Sang-Won Min et al. NEURON
- ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import
- (2010) Q. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
- (2010) S.-C. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nitroproteomics of Peripheral Blood Mononuclear Cells from Patients and a Rat Model of ALS
- (2009) Giovanni Nardo et al. ANTIOXIDANTS & REDOX SIGNALING
- Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord
- (2009) Jianjun Zhai et al. FEBS Journal
- Tau - an inhibitor of deacetylase HDAC6 function
- (2009) Mar Perez et al. JOURNAL OF NEUROCHEMISTRY
- Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
- (2009) Brian D. Freibaum et al. JOURNAL OF PROTEOME RESEARCH
- Changes in the Spinal Cord Proteome of an Amyotrophic Lateral Sclerosis Murine Model Determined by Differential In-gel Electrophoresis
- (2009) Daniel Bergemalm et al. MOLECULAR & CELLULAR PROTEOMICS
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Characterization of Detergent-Insoluble Proteins in ALS Indicates a Causal Link between Nitrative Stress and Aggregation in Pathogenesis
- (2009) Manuela Basso et al. PLoS One
- Proteomic analysis of plasma from Portuguese patients with familial amyotrophic lateral sclerosis
- (2008) Angelina S. Palma et al. Amyotrophic Lateral Sclerosis
- Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
- (2008) Masato Hasegawa et al. ANNALS OF NEUROLOGY
- Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
- (2008) R. I. Morimoto GENES & DEVELOPMENT
- Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis†
- (2008) Cristina Cheroni et al. HUMAN MOLECULAR GENETICS
- Protein Folding and Misfolding on Surfaces
- (2008) Massimo Stefani INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural determinants of the cellular localization and shuttling of TDP-43
- (2008) Y. M. Ayala et al. JOURNAL OF CELL SCIENCE
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- Quantitative phosphoproteomics by mass spectrometry: Past, present, and future
- (2008) Aleksandra Nita-Lazar et al. PROTEOMICS
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
- TDP-43: an emerging new player in neurodegenerative diseases
- (2008) I-Fan Wang et al. TRENDS IN MOLECULAR MEDICINE
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