Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1

Distinct functional roles of cytoplasmic dynein defined by the intermediate chain isoforms

(2015) K. Kevin Pfister   EXPERIMENTAL CELL RESEARCH

C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis

(2015) Jonathan D Rohrer et al.   LANCET NEUROLOGY

Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number

(2014) Alejandra Gardiol et al.   DEVELOPMENTAL BIOLOGY

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

Human Staufen1 Associates to MiRNAs Involved in Neuronal Cell Differentiation and is Required for Correct Dendritic Formation

(2014) Joan Peredo et al.   PLoS One

Integrated regulation of motor-driven organelle transport by scaffolding proteins

(2014) Meng-meng Fu et al.   TRENDS IN CELL BIOLOGY

The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity

(2014) Jacki E. Heraud-Farlow et al.   TRENDS IN NEUROSCIENCES

RNA metabolism in ALS: When normal processes become pathological

(2014) Cristian A. Droppelmann et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease

(2014) Elizabeth B. Moloney et al.   Frontiers in Neuroscience

Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions

(2013) Jun Zhang et al.   Cytoskeleton

Dynein Interacts with the Neural Cell Adhesion Molecule (NCAM180) to Tether Dynamic Microtubules and Maintain Synaptic Density in Cortical Neurons

(2013) Eran Perlson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ordered Recruitment of Dynactin to the Microtubule Plus-End is Required for Efficient Initiation of Retrograde Axonal Transport

(2013) A. J. Moughamian et al.   JOURNAL OF NEUROSCIENCE

Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis

(2013) Shusheng Wang et al.   MOLECULAR BIOLOGY OF THE CELL

dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration

(2013) Kensuke Ikenaka et al.   PLoS One

Releasing the brake: restoring fast axonal transport in neurodegenerative disorders

(2013) Maria-Victoria Hinckelmann et al.   TRENDS IN CELL BIOLOGY

Neurodegeneration-associated TDP-43 Interacts with Fragile X Mental Retardation Protein (FMRP)/Staufen (STAU1) and Regulates SIRT1 Expression in Neuronal Cells

(2012) Zhipeng Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cortical dynein is critical for proper spindle positioning in human cells

(2012) Sachin Kotak et al.   JOURNAL OF CELL BIOLOGY

Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

(2012) Tomomi Kiyomitsu et al.   NATURE CELL BIOLOGY

Quantitative Proteomic Analysis of Human Substantia Nigra in Alzheimer’s Disease, Huntington’s Disease and Multiple Sclerosis

(2012) Sheng Chen et al.   NEUROCHEMICAL RESEARCH

The p150Glued CAP-Gly Domain Regulates Initiation of Retrograde Transport at Synaptic Termini

(2012) Thomas E. Lloyd et al.   NEURON

Dynactin Is Required for Transport Initiation from the Distal Axon

(2012) Armen J. Moughamian et al.   NEURON

HIPPIE: Integrating Protein Interaction Networks with Experiment Based Quality Scores

(2012) Martin H. Schaefer et al.   PLoS One

Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin

(2011) Richard J. McKenney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic dynein in neurodegeneration

(2011) Judith Eschbach et al.   PHARMACOLOGY & THERAPEUTICS

ANAT: A Tool for Constructing and Analyzing Functional Protein Networks

(2011) N. Yosef et al.   Science Signaling

Interaction proteomics of synapse protein complexes

(2010) Ka Wan Li et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Dendritically Localized Transcripts Are Sorted into Distinct Ribonucleoprotein Particles That Display Fast Directional Motility along Dendrites of Hippocampal Neurons

(2010) F. Tubing et al.   JOURNAL OF NEUROSCIENCE

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Nitroproteomics of Peripheral Blood Mononuclear Cells from Patients and a Rat Model of ALS

(2009) Giovanni Nardo et al.   ANTIOXIDANTS & REDOX SIGNALING

bioDBnet: the biological database network

(2009) Uma Mudunuri et al.   BIOINFORMATICS

Transmitting the message: intracellular mRNA localization

(2009) Carine Meignin et al.   CURRENT OPINION IN CELL BIOLOGY

Axonal Transport Proteomics Reveals Mobilization of Translation Machinery to the Lesion Site in Injured Sciatic Nerve

(2009) Izhak Michaelevski et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of Detergent-Insoluble Proteins in ALS Indicates a Causal Link between Nitrative Stress and Aggregation in Pathogenesis

(2009) Manuela Basso et al.   PLoS One

Subcellular mRNA Localization in Animal Cells and Why It Matters

(2009) C. E. Holt et al.   SCIENCE

Perception of the acoustic environment and neuroimaging findings: a report of six cases with a history of closed head injury

(2008) Per-Olof Bergemalm et al.   ACTA OTO-LARYNGOLOGICA

Proteomic analysis of plasma from Portuguese patients with familial amyotrophic lateral sclerosis

(2008) Angelina S. Palma et al.   Amyotrophic Lateral Sclerosis

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

Proteomic and oxidative stress analysis in human brain samples of Huntington disease

(2008) M Alba Sorolla et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis

(2008) Jacqueline Whyte et al.   JOURNAL OF CELL BIOLOGY

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

(2008) I.-Fan Wang et al.   JOURNAL OF NEUROCHEMISTRY

Proteomics analysis of immuno-precipitated synaptic protein complexes

(2008) P. Klemmer et al.   Journal of Proteomics

A Large Number of Protein Expression Changes Occur Early in Life and Precede Phenotype Onset in a Mouse Model for Huntington Disease

(2008) Claus Zabel et al.   MOLECULAR & CELLULAR PROTEOMICS

Staufen1 Regulation of Protein Synthesis-Dependent Long-Term Potentiation and Synaptic Function in Hippocampal Pyramidal Cells

(2008) G. Lebeau et al.   MOLECULAR AND CELLULAR BIOLOGY

Proteomics of human cerebral microdialysate: From detection of biomarkers to clinical application

(2008) Martin H. Maurer et al.   Proteomics Clinical Applications