Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients

Published 2017 View Full Article

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Title
Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients
Authors
Keywords
pre-mRNA splicing, U2 snRNP, ALS, FTD, C9ORF72, toxic polydipeptide repeats, DPRs, poly-GR, poly-PR, iPSC-derived motor neurons
Journal
Cell Reports
Volume 19, Issue 11, Pages 2244-2256
Publisher
Elsevier BV
Online
2017-06-14
DOI
10.1016/j.celrep.2017.05.056

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