Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS
Authors
Keywords
ALS, Na<sup>+</sup>/K<sup>+</sup>ATPase-α3, SOD1 interactome, Motor neuron excitability, Sporadic and familial ALS
Journal
ACTA NEUROPATHOLOGICA
Volume 131, Issue 3, Pages 427-451
Publisher
Springer Nature
Online
2015-11-30
DOI
10.1007/s00401-015-1510-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Homeostatic Dysregulation in Membrane Properties of Masticatory Motoneurons Compared with Oculomotor Neurons in a Mouse Model for Amyotrophic Lateral Sclerosis
- (2015) S. Venugopal et al. JOURNAL OF NEUROSCIENCE
- Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping
- (2015) Johan Bergh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
- (2015) Anna-Claire Devlin et al. Nature Communications
- A Computational Model of Motor Neuron Degeneration
- (2014) Gwendal Le Masson et al. NEURON
- Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons
- (2014) Brian J. Wainger et al. Cell Reports
- Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis
- (2014) Félix Leroy et al. eLife
- Intracerebroventricular Injection of Adeno-Associated Virus 6 and 9 Vectors for Cell Type–Specific Transgene Expression in the Spinal Cord
- (2013) Elisabeth Dirren et al. HUMAN GENE THERAPY
- Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability
- (2013) Elsa Fritz et al. JOURNAL OF NEUROPHYSIOLOGY
- Alterations on Na+,K+-ATPase and Acetylcholinesterase Activities Induced by Amyloid-β Peptide in Rat Brain and GM1 Ganglioside Neuroprotective Action
- (2013) Fernando Kreutz et al. NEUROCHEMICAL RESEARCH
- Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival
- (2013) Smita Saxena et al. NEURON
- An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis
- (2013) Melissa S. Rotunno et al. Frontiers in Cellular Neuroscience
- Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry
- (2012) Kapila Gunasekera et al. BMC GENOMICS
- A Specific and Essential Role for Na,K-ATPase α3 in Neurons Co-expressing α1 and α3
- (2012) Guillaume Azarias et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting of Monomer/Misfolded SOD1 as a Therapeutic Strategy for Amyotrophic Lateral Sclerosis
- (2012) H.-N. Liu et al. JOURNAL OF NEUROSCIENCE
- Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy
- (2012) Ali Al Kaabi et al. PLoS One
- An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1
- (2012) S. Guareschi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Motoneuron afterhyperpolarisation duration in amyotrophic lateral sclerosis
- (2011) Maria Piotrkiewicz et al. JOURNAL OF PHYSIOLOGY-LONDON
- Selective Neuronal Vulnerability in Neurodegenerative Diseases: from Stressor Thresholds to Degeneration
- (2011) Smita Saxena et al. NEURON
- The Physiological Significance of the Cardiotonic Steroid/Ouabain-Binding Site of the Na,K-ATPase
- (2010) Jerry B Lingrel Annual Review of Physiology
- Identification of novel spinal cholinergic genetic subtypes disclose Chodl and Pitx2 as markers for fast motor neurons and partition cells
- (2010) Anders Enjin et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- Increase in presynaptic territory of C-terminals on lumbar motoneurons of G93A SOD1 mice during disease progression
- (2009) A. H. Pullen et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Upregulation of persistent sodium conductances in familial ALS
- (2009) S. Vucic et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Incidence of amyotrophic lateral sclerosis in Europe
- (2009) G. Logroscino et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Early Excitability Changes in Lumbar Motoneurons of Transgenic SOD1G85R and SOD1G93A-Low Mice
- (2009) Arnaud Pambo-Pambo et al. JOURNAL OF NEUROPHYSIOLOGY
- Na,K-ATPase Activity Regulates AMPA Receptor Turnover through Proteasome-Mediated Proteolysis
- (2009) D. Zhang et al. JOURNAL OF NEUROSCIENCE
- Crystal structure of the sodium–potassium pump at 2.4 Å resolution
- (2009) Takehiro Shinoda et al. NATURE
- A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
- (2009) Smita Saxena et al. NATURE NEUROSCIENCE
- Glycinergic Innervation of Motoneurons Is Deficient in Amyotrophic Lateral Sclerosis Mice
- (2008) Qing Chang et al. AMERICAN JOURNAL OF PATHOLOGY
- ALSOD: The Amyotrophic Lateral Sclerosis Online Database
- (2008) Richard Wroe et al. Amyotrophic Lateral Sclerosis
- Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis
- (2008) Steve Vucic et al. BRAIN
- ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
- (2008) H. Nishitoh et al. GENES & DEVELOPMENT
- Preferential motor unit loss in the SOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis
- (2008) J. Hegedus et al. JOURNAL OF PHYSIOLOGY-LONDON
- Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis
- (2008) Julie D. Atkin et al. NEUROBIOLOGY OF DISEASE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now