Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

Evidence that Non-Fibrillar Tau Causes Pathology Linked to Neurodegeneration and Behavioral Impairments

(2017) Kurt R. Brunden et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau pathology in children and young adults: can you still be unconditionally baptist?

(2011) Charles Duyckaerts   ACTA NEUROPATHOLOGICA

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila

(2011) Yasmina Talmat-Amar et al.   HUMAN MOLECULAR GENETICS

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

(2011) Jack Reifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β Annular Protofibrils Evade Fibrillar Fate in Alzheimer Disease Brain

(2011) Cristian A. Lasagna-Reeves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Prefibrillar Tau Oligomersin Vitroand in Alzheimer Disease

(2011) Kristina R. Patterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Are Tangles as Toxic as They Look?

(2011) Tara L. Spires-Jones et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

(2011) A. Sydow et al.   JOURNAL OF NEUROSCIENCE

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

(2011) Rakez Kayed et al.   Molecular Neurodegeneration

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Preparation and Characterization of Neurotoxic Tau Oligomers

(2010) Cristian A. Lasagna-Reeves et al.   BIOCHEMISTRY

Intra and Extracellular Protein Interactions with Tau

(2010) F. Hernandez et al.   Current Alzheimer Research

Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau

(2010) Miguel Díaz-Hernández et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Prion-like transmission of protein aggregates in neurodegenerative diseases

(2010) Patrik Brundin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions

(2009) Byron Caughey et al.   Annual Review of Biochemistry

Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study

(2009) G. Lace et al.   BRAIN

Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders

(2009) Rakez Kayed et al.   CURRENT OPINION IN IMMUNOLOGY

Rapid Progression from Mild Cognitive Impairment to Alzheimer’s Disease in Subjects with Elevated Levels of Tau in Cerebrospinal Fluid and the APOE ε4/ε4 Genotype

(2009) Elin S. Blom et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation

(2009) Dominik Paquet et al.   JOURNAL OF CLINICAL INVESTIGATION

Tau oligomers and aggregation in Alzheimer’s disease

(2009) Marco A. Meraz-Ríos et al.   JOURNAL OF NEUROCHEMISTRY

Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

(2009) M. Polydoro et al.   JOURNAL OF NEUROSCIENCE

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Prion-like mechanisms in neurodegenerative diseases

(2009) Bess Frost et al.   NATURE REVIEWS NEUROSCIENCE

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies

(2008) Robert Adalbert et al.   BRAIN

Mechanism of Tau-Induced Neurodegeneration in Alzheimer Disease and Related Tauopathies

(2008) Alejandra del Alonso et al.   Current Alzheimer Research

Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model

(2008) Shreyasi Chatterjee et al.   HUMAN MOLECULAR GENETICS

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

The Potential for -Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

(2008) M.-M. Mocanu et al.   JOURNAL OF NEUROSCIENCE

Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

(2008) A. Gómez-Ramos et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis

(2008) Scott A. Small et al.   NEURON