Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

Neuroinflammation in Amyotrophic Lateral Sclerosis: Role of Redox (dys)Regulation

(2018) Nadia D'Ambrosi et al.   ANTIOXIDANTS & REDOX SIGNALING

CSF cystatin C and diffusion tensor imaging parameters as biomarkers of upper motor neuron degeneration in amyotrophic lateral sclerosis

(2018) Shunya Nakane et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Metabotropic glutamate receptor involvement in the pathophysiology of amyotrophic lateral sclerosis: new potential drug targets for therapeutic applications

(2018) Giuseppe Battaglia et al.   CURRENT OPINION IN PHARMACOLOGY

Selenoprotein T is a key player in ER proteostasis, endocrine homeostasis and neuroprotection

(2018) Youssef Anouar et al.   FREE RADICAL BIOLOGY AND MEDICINE

“In vitro” studies on galectin-3 in human natural killer cells

(2018) Alvaro Brittoli et al.   IMMUNOLOGY LETTERS

Delivery of an anti-transthyretin Nanobody to the brain through intranasal administration reveals transthyretin expression and secretion by motor neurons

(2018) João R. Gomes et al.   JOURNAL OF NEUROCHEMISTRY

TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

(2018) Stephani A. Davis et al.   NEUROSCIENCE LETTERS

The role of galectin-3 in the tumorigenesis and progression of pituitary tumors

(2018) Bo Diao et al.   Oncology Letters

Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism

(2018) Erin G Conlon et al.   eLife

Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum

(2018) Celeste M. Karch et al.   JAMA Neurology

Investigation of Gal-3 Expression Pattern in Serum and Cerebrospinal Fluid of Patients Suffering From Neurodegenerative Disorders

(2018) Ghulam M. Ashraf et al.   Frontiers in Neuroscience

Comparison of elevated phosphorylated neurofilament heavy chains in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis

(2017) Maxim De Schaepdryver et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Elevated Levels of Selenium Species in Cerebrospinal Fluid of Amyotrophic Lateral Sclerosis Patients with Disease-Associated Gene Mutations

(2017) Jessica Mandrioli et al.   Neurodegenerative Diseases

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria

(2017) Michael J. Strong et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Amyotrophic lateral sclerosis

(2017) Orla Hardiman et al.   Nature Reviews Disease Primers

Stress-Dependent Changes in the CacyBP/SIP Interacting Protein S100A6 in the Mouse Brain

(2017) Katarzyna Bartkowska et al.   PLoS One

Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression

(2017) Mercedes Lachén-Montes et al.   Scientific Reports

Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia

(2016) J R Gomes et al.   CELL DEATH AND DIFFERENTIATION

Increased Expressions of Plasma Galectin-3 in Patients with Amyotrophic Lateral Sclerosis

(2016) Ling Chen et al.   CHINESE MEDICAL JOURNAL

ALS‐linked protein disulfide isomerase variants cause motor dysfunction

(2016) Ute Woehlbier et al.   EMBO JOURNAL

Amyotrophic lateral sclerosis: moving towards a new classification system

(2016) Ammar Al-Chalabi et al.   LANCET NEUROLOGY

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

Gene discovery in amyotrophic lateral sclerosis: implications for clinical management

(2016) Ammar Al-Chalabi et al.   Nature Reviews Neurology

Specific Legislation on Biobanks in Spain

(2015) Isabel M García-Merino et al.   BIOPRESERVATION AND BIOBANKING

Galectin-3 in autoimmunity and autoimmune diseases

(2015) Felipe L de Oliveira et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The Diversity of Mechanisms Influenced by Transthyretin in Neurobiology: Development, Disease and Endocrine Disruption

(2015) B. Alshehri et al.   JOURNAL OF NEUROENDOCRINOLOGY

Downregulated AEG-1 together with inhibited PI3K/Akt pathway is associated with reduced viability of motor neurons in an ALS model

(2015) Xiang Yin et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

An Assessment of Possible Neuropathology and Clinical Relationships in 46 Sporadic Amyotrophic Lateral Sclerosis Patient Autopsies

(2015) Grant Coan et al.   Neurodegenerative Diseases

Specific Legislation on Biobanks in Spain

(2015) Isabel M García-Merino et al.   Biopreservation and Biobanking

Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes

(2014) Janet Cady et al.   ANNALS OF NEUROLOGY

Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study

(2014) Ching-Hua Lu et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Alterations in muscle proteome of patients diagnosed with amyotrophic lateral sclerosis

(2014) Kristin Elf et al.   Journal of Proteomics

Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study

(2014) Ammar Al-Chalabi et al.   LANCET NEUROLOGY

Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS

(2014) Bradley N. Smith et al.   NEURON

Microglia centered pathogenesis in ALS: insights in cell interconnectivity

(2014) Dora Brites et al.   Frontiers in Cellular Neuroscience

Mechanisms of mutant SOD1 induced mitochondrial toxicity in amyotrophic lateral sclerosis

(2014) Piia Vehviläinen et al.   Frontiers in Cellular Neuroscience

Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain

(2014) S A Shah et al.   Cell Death & Disease

Elevated Galectin-3 Levels in the Serum of Patients With Alzheimer's Disease

(2013) Xuexin Wang et al.   American Journal of Alzheimers Disease and Other Dementias

Increased expression of Myosin binding protein H in the skeletal muscle of amyotrophic lateral sclerosis patients

(2013) Antonio Conti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis

(2013) Thomas Philips et al.   BRAIN

Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis

(2013) Lars Tönges et al.   GLIA

Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature

(2013) A. Chiò et al.   NEUROEPIDEMIOLOGY

Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease

(2013) Magdalena Czeredys et al.   Frontiers in Molecular Neuroscience

S100A6 Amyloid Fibril Formation Is Calcium-modulated and Enhances Superoxide Dismutase-1 (SOD1) Aggregation

(2012) Hugo M. Botelho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcyclin binding protein and Siah-1 interacting protein in Alzheimer's disease pathology: neuronal localization and possible function

(2012) Urszula Wasik et al.   NEUROBIOLOGY OF AGING

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

(2011) Alan E. Renton et al.   NEURON

Galectin-3 Is a Candidate Biomarker for Amyotrophic Lateral Sclerosis: Discovery by a Proteomics Approach

(2010) Jian-Ying Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

Cystatin C: A Candidate Biomarker for Amyotrophic Lateral Sclerosis

(2010) Meghan E. Wilson et al.   PLoS One

Cerebrospinal fluid and serum antibodies against neurofilaments in patients with amyotrophic lateral sclerosis

(2009) L. Fialová et al.   EUROPEAN JOURNAL OF NEUROLOGY

Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

(2009) P. Rudrabhatla et al.   JOURNAL OF NEUROSCIENCE

Proteome analysis reveals candidate markers of disease progression in amyotrophic lateral sclerosis (ALS)

(2009) Johannes Brettschneider et al.   NEUROSCIENCE LETTERS