Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume 25, Issue 9, Pages 1803-1813
Publisher
Oxford University Press (OUP)
Online
2016-03-02
DOI
10.1093/hmg/ddw052
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nuclear accumulation of mRNAs underlies G4C2-repeat-induced translational repression in a cellular model of C9orf72 ALS
- (2015) S. Rossi et al. JOURNAL OF CELL SCIENCE
- Emerging mechanisms of molecular pathology in ALS
- (2015) Owen M. Peters et al. JOURNAL OF CLINICAL INVESTIGATION
- Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
- (2014) Mai Yamakawa et al. HUMAN MOLECULAR GENETICS
- Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome
- (2014) Eileen Chen et al. MOLECULAR CELL
- C9orf72 nucleotide repeat structures initiate molecular cascades of disease
- (2014) Aaron R. Haeusler et al. NATURE
- Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS
- (2014) Zhaoming Su et al. NEURON
- Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
- (2014) Xinmei Wen et al. NEURON
- C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
- (2014) S. Mizielinska et al. SCIENCE
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
- (2014) I. Kwon et al. SCIENCE
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
- (2012) Elisa Majounie et al. LANCET NEUROLOGY
- Sustained translational repression by eIF2α-P mediates prion neurodegeneration
- (2012) Julie A. Moreno et al. NATURE
- Translational control in cellular and developmental processes
- (2012) Jian Kong et al. NATURE REVIEWS GENETICS
- C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
- (2012) Pietro Fratta et al. Scientific Reports
- Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism
- (2012) Thomas D. Baird et al. Advances in Nutrition
- FTD and ALS: A Tale of Two Diseases
- (2011) R. Ferrari et al. Current Alzheimer Research
- Phosphorylation of Eukaryotic Translation Initiation Factor 4B (EIF4B) by Open Reading Frame 45/p90 Ribosomal S6 Kinase (ORF45/RSK) Signaling Axis Facilitates Protein Translation during Kaposi Sarcoma-associated Herpesvirus (KSHV) Lytic Replication
- (2011) Ersheng Kuang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Network-based Auto-probit Modeling for Protein Function Prediction
- (2010) Xiaoyu Jiang et al. BIOMETRICS
- Arginine-Rich Peptides Destabilize the Plasma Membrane, Consistent with a Pore Formation Translocation Mechanism of Cell-Penetrating Peptides
- (2009) H.D. Herce et al. BIOPHYSICAL JOURNAL
- SUnSET, a nonradioactive method to monitor protein synthesis
- (2009) Enrico K Schmidt et al. NATURE METHODS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started