Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

(2015) Di Xia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Misfolded proteins, mitochondrial dysfunction, and neurodegenerative diseases

(2014) P. Hemachandra Reddy   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans

(2014) Milena Ullrich et al.   Nature Protocols

Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses

(2014) Tatsuya Mishima et al.   PLoS One

Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

(2014) Hans Zempel et al.   TRENDS IN NEUROSCIENCES

Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn

(2014) Di Xia et al.   Frontiers in Molecular Neuroscience

Measuring and Managing Ratio Compression for Accurate iTRAQ/TMT Quantification

(2013) Mikhail M. Savitski et al.   JOURNAL OF PROTEOME RESEARCH

Increased Tau Phosphorylation and Tau Truncation, and Decreased Synaptophysin Levels in Mutant BRI2/Tau Transgenic Mice

(2013) Holly J. Garringer et al.   PLoS One

Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus

(2013) Chang Liu et al.   PLoS One

What Renders TAU Toxic

(2013) Jürgen Götz et al.   Frontiers in Neurology

The Protein Phosphatase PP2A/Bα Binds to the Microtubule-associated Proteins Tau and MAP2 at a Motif Also Recognized by the Kinase Fyn

(2012) Jean-Marie Sontag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic strategies for tau mediated neurodegeneration

(2012) Y. Yoshiyama et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo

(2012) Brian DuBoff et al.   NEURON

Loss of Axonal Mitochondria Promotes Tau-Mediated Neurodegeneration and Alzheimer's Disease–Related Tau Phosphorylation Via PAR-1

(2012) Kanae Iijima-Ando et al.   PLoS Genetics

Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain

(2011) Katherine J. Kopeikina et al.   AMERICAN JOURNAL OF PATHOLOGY

The Nucleotide-binding State of Microtubules Modulates Kinesin Processivity and the Ability of Tau to Inhibit Kinesin-mediated Transport

(2011) Derrick P. McVicker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

(2011) E. D. Roberson et al.   JOURNAL OF NEUROSCIENCE

Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy

(2011) Nahuai Badiola et al.   PLoS One

Functional implications of the association of tau with the plasma membrane

(2010) Amy M. Pooler et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

(2010) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer’s disease

(2009) Alex E. Roher et al.   BIOMARKERS

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

(2009) Esperanza Fernández et al.   Molecular Systems Biology

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Growth Factor-Dependent Trafficking of Cerebellar NMDA Receptors via Protein Kinase B/Akt Phosphorylation of NR2C

(2009) Bo-Shiun Chen et al.   NEURON

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

(2009) V. Rhein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tau isoform regulation is region- and cell-specific in mouse brain

(2008) Pamela McMillan et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH