- Home
- Publications
- Publication Search
- Publication Details
Title
Emerging views of the nucleus as a cellular mechanosensor
Authors
Keywords
-
Journal
NATURE CELL BIOLOGY
Volume 20, Issue 4, Pages 373-381
Publisher
Springer Nature
Online
2018-02-21
DOI
10.1038/s41556-018-0038-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins
- (2018) Andrew D. Stephens et al. MOLECULAR BIOLOGY OF THE CELL
- Nuclear Lamins: Thin Filaments with Major Functions
- (2018) Rebecca de Leeuw et al. TRENDS IN CELL BIOLOGY
- Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle
- (2017) Matthew J. Stroud et al. JOURNAL OF CELL BIOLOGY
- Mechanosensing by the nucleus: From pathways to scaling relationships
- (2017) Sangkyun Cho et al. JOURNAL OF CELL BIOLOGY
- Emerging roles of mechanical forces in chromatin regulation
- (2017) Yekaterina A. Miroshnikova et al. JOURNAL OF CELL SCIENCE
- Tissue mechanics regulate brain development, homeostasis and disease
- (2017) J. Matthew Barnes et al. JOURNAL OF CELL SCIENCE
- Super-resolution microscopy approaches to nuclear nanostructure imaging
- (2017) Christoph Cremer et al. METHODS
- Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes
- (2017) Amnon Buxboim et al. MOLECULAR BIOLOGY OF THE CELL
- Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus
- (2017) Andrew D. Stephens et al. MOLECULAR BIOLOGY OF THE CELL
- Orientation and repositioning of chromosomes correlate with cell geometry–dependent gene expression
- (2017) Yejun Wang et al. MOLECULAR BIOLOGY OF THE CELL
- Emery–Dreifuss muscular dystrophy–linked genes and centronuclear myopathy–linked genes regulate myonuclear movement by distinct mechanisms
- (2017) Mary Ann Collins et al. MOLECULAR BIOLOGY OF THE CELL
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle
- (2017) William Roman et al. NATURE CELL BIOLOGY
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Piezos thrive under pressure: mechanically activated ion channels in health and disease
- (2017) Swetha E. Murthy et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability
- (2017) Tohru Takaki et al. Nature Communications
- Consequences of a tight squeeze: Nuclear envelope rupture and repair
- (2017) Philipp Isermann et al. Nucleus
- Nuclear membrane stretch and its role in mechanotransduction
- (2017) Balázs Enyedi et al. Nucleus
- Consequences of a tight squeeze: Nuclear envelope rupture and repair
- (2017) Philipp Isermann et al. Nucleus
- Nuclear membrane stretch and its role in mechanotransduction
- (2017) Balázs Enyedi et al. Nucleus
- Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension
- (2016) Paul T. Arsenovic et al. BIOPHYSICAL JOURNAL
- The Cell Nucleus Serves as a Mechanotransducer of Tissue Damage-Induced Inflammation
- (2016) Balázs Enyedi et al. CELL
- Mechanobiology of Chromatin and the Nuclear Interior
- (2016) Stephen T. Spagnol et al. Cellular and Molecular Bioengineering
- Nuclear envelope rupture: Actin fibers are putting the squeeze on the nucleus
- (2016) Jan Lammerding et al. JOURNAL OF CELL BIOLOGY
- Nuclear envelope rupture is induced by actin-based nucleus confinement
- (2016) Emily M. Hatch et al. JOURNAL OF CELL BIOLOGY
- Integrin-mediated mechanotransduction
- (2016) Zhiqi Sun et al. JOURNAL OF CELL BIOLOGY
- Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation
- (2016) Noam Zuela et al. JOURNAL OF CELL SCIENCE
- The LINC and NPC relationship – it's complicated!
- (2016) Zeinab Jahed et al. JOURNAL OF CELL SCIENCE
- Nuclear migration events throughout development
- (2016) Courtney R. Bone et al. JOURNAL OF CELL SCIENCE
- Super-resolution imaging reveals distinct chromatin folding for different epigenetic states
- (2016) Alistair N. Boettiger et al. NATURE
- Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment
- (2016) Huy Quang Le et al. NATURE CELL BIOLOGY
- Transcription upregulation via force-induced direct stretching of chromatin
- (2016) Arash Tajik et al. NATURE MATERIALS
- Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system
- (2016) Shipeng Shao et al. NUCLEIC ACIDS RESEARCH
- ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
- (2016) M. Raab et al. SCIENCE
- Nuclear envelope rupture and repair during cancer cell migration
- (2016) C. M. Denais et al. SCIENCE
- Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments
- (2016) Hawa-Racine Thiam et al. Nature Communications
- Unravelling a new mechanism linking actin polymerization and gene transcription
- (2016) Susanne Muehlich et al. Nucleus
- Unravelling a new mechanism linking actin polymerization and gene transcription
- (2016) Susanne Muehlich et al. Nucleus
- In silico synchronization reveals regulators of nuclear ruptures in lamin A/C deficient model cells
- (2016) J. Robijns et al. Scientific Reports
- Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells
- (2015) Tristan P. Driscoll et al. BIOPHYSICAL JOURNAL
- 53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair
- (2015) Francisca Lottersberger et al. CELL
- Chromatin Fibers Are Formed by Heterogeneous Groups of Nucleosomes In Vivo
- (2015) Maria Aurelia Ricci et al. CELL
- Nuclear membrane diversity: underlying tissue-specific pathologies in disease?
- (2015) Howard J Worman et al. CURRENT OPINION IN CELL BIOLOGY
- Lamins at the crossroads of mechanosignaling
- (2015) Selma Osmanagic-Myers et al. GENES & DEVELOPMENT
- Plectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers
- (2015) Ilona Staszewska et al. HUMAN MOLECULAR GENETICS
- Accessorizing and anchoring the LINC complex for multifunctionality
- (2015) Wakam Chang et al. JOURNAL OF CELL BIOLOGY
- Nuclear–cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions
- (2015) Rachel M. Stewart et al. JOURNAL OF CELL BIOLOGY
- Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins
- (2015) Jennifer C. Harr et al. JOURNAL OF CELL BIOLOGY
- Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins
- (2015) M. Zwerger et al. JOURNAL OF CELL SCIENCE
- The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts
- (2015) S. G. Alam et al. JOURNAL OF CELL SCIENCE
- Cytoskeletal Control of Nuclear Morphology and Chromatin Organization
- (2015) Nisha M. Ramdas et al. JOURNAL OF MOLECULAR BIOLOGY
- Differential basal-to-apical accessibility of lamin A/C epitopes in the nuclear lamina regulated by changes in cytoskeletal tension
- (2015) Teemu O. Ihalainen et al. NATURE MATERIALS
- Multicolor CRISPR labeling of chromosomal loci in human cells
- (2015) Hanhui Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional organization of the human 4D Nucleome
- (2015) Haiming Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell
- (2015) Srujana Neelam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear deformability and telomere dynamics are regulated by cell geometric constraints
- (2015) Ekta Makhija et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal structure of the metazoan Nup62bulletNup58bulletNup54 nucleoporin complex
- (2015) H. Chug et al. SCIENCE
- Architecture of the fungal nuclear pore inner ring complex
- (2015) T. Stuwe et al. SCIENCE
- Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts
- (2015) Wakam Chang et al. Nucleus
- Linker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts
- (2015) Wakam Chang et al. Nucleus
- Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments
- (2014) Patricia M. Davidson et al. Cellular and Molecular Bioengineering
- Linker of Nucleoskeleton and Cytoskeleton Complex Proteins in Cardiac Structure, Function, and Disease
- (2014) Matthew J Stroud et al. CIRCULATION RESEARCH
- Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin
- (2014) Amnon Buxboim et al. CURRENT BIOLOGY
- Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration
- (2014) Samantha J. King et al. Cytoskeleton
- Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells
- (2014) M. H. Wilson et al. DEVELOPMENT
- Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival
- (2014) Takamasa Harada et al. JOURNAL OF CELL BIOLOGY
- Cellular microenvironments reveal defective mechanosensing responses and elevated YAP signaling in LMNA-mutated muscle precursors
- (2014) A. T. Bertrand et al. JOURNAL OF CELL SCIENCE
- The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue
- (2014) J. Swift et al. JOURNAL OF CELL SCIENCE
- Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus
- (2014) Christophe Guilluy et al. NATURE CELL BIOLOGY
- Mechanotransduction and extracellular matrix homeostasis
- (2014) Jay D. Humphrey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Appreciating force and shape — the rise of mechanotransduction in cell biology
- (2014) Thomas Iskratsch et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nanoscale Protein Diffusion by STED-Based Pair Correlation Analysis
- (2014) Paolo Bianchini et al. PLoS One
- Cellular mechanosensing: Getting to the nucleus of it all
- (2014) Gregory R. Fedorchak et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Nuclear Envelope Lamin-A Couples Actin Dynamics with Immunological Synapse Architecture and T Cell Activation
- (2014) J. M. Gonzalez-Granado et al. Science Signaling
- Targeted Ablation of Nesprin 1 and Nesprin 2 from Murine Myocardium Results in Cardiomyopathy, Altered Nuclear Morphology and Inhibition of the Biomechanical Gene Response
- (2014) Indroneal Banerjee et al. PLoS Genetics
- LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation
- (2013) Irina Solovei et al. CELL
- Integrins in mechanotransduction
- (2013) Tyler D Ross et al. CURRENT OPINION IN CELL BIOLOGY
- Morphology and function of membrane-bound organelles
- (2013) Rebecca Heald et al. CURRENT OPINION IN CELL BIOLOGY
- Nesprins: from the nuclear envelope and beyond
- (2013) Dipen Rajgor et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling
- (2013) Monika Zwerger et al. HUMAN MOLECULAR GENETICS
- A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
- (2013) Sébastien Britton et al. JOURNAL OF CELL BIOLOGY
- Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
- (2013) Takashi Nagano et al. NATURE
- RecA bundles mediate homology pairing between distant sisters during DNA break repair
- (2013) Christian Lesterlin et al. NATURE
- Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics
- (2013) Chin Yee Ho et al. NATURE
- Probing the compressibility of tumor cell nuclei by combined atomic force–confocal microscopy
- (2013) Marina Krause et al. PHYSICAL BIOLOGY
- Ring cycle for dilating and constricting the nuclear pore
- (2013) S. R. Solmaz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
- (2013) J. Swift et al. SCIENCE
- The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
- (2013) Allison B. Chambliss et al. Scientific Reports
- Force-Induced Changes in Subnuclear Movement and Rheology
- (2012) Elizabeth A. Booth-Gauthier et al. BIOPHYSICAL JOURNAL
- Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells
- (2012) Kevin J. Chalut et al. BIOPHYSICAL JOURNAL
- DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina
- (2012) Joseph M. Zullo et al. CELL
- Fine control of nuclear confinement identifies a threshold deformation leading to lamina rupture and induction of specific genes
- (2012) Maël Le Berre et al. Integrative Biology
- Lamins at a glance
- (2012) C. Y. Ho et al. JOURNAL OF CELL SCIENCE
- Hi–C: A comprehensive technique to capture the conformation of genomes
- (2012) Jon-Matthew Belton et al. METHODS
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration
- (2012) Shyam B. Khatau et al. Scientific Reports
- Transient nuclear envelope rupturing during interphase in human cancer cells
- (2012) Jesse D. Vargas et al. Nucleus
- PALM and STORM: Unlocking live-cell super-resolution
- (2011) Ricardo Henriques et al. BIOPOLYMERS
- Nuclear organization: taking a position on gene expression
- (2011) Pamela K Geyer et al. CURRENT OPINION IN CELL BIOLOGY
- Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies
- (2011) Winnok H. De Vos et al. HUMAN MOLECULAR GENETICS
- The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton
- (2011) Maria L. Lombardi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Post-natal myogenic and adipogenic developmental
- (2011) Nard Kubben et al. Nucleus
- Mechanisms Determining the Morphology of the Peripheral ER
- (2010) Yoko Shibata et al. CELL
- Real Time FRET Based Detection of Mechanical Stress in Cytoskeletal and Extracellular Matrix Proteins
- (2010) Fanjie Meng et al. Cellular and Molecular Bioengineering
- Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
- (2010) Carsten Grashoff et al. NATURE
- Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement
- (2010) E. S. Folker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration
- (2009) Heidi N. Fridolfsson et al. DEVELOPMENTAL BIOLOGY
- Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases
- (2009) K. E. Tifft et al. JOURNAL OF CELL SCIENCE
- Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse
- (2009) Mihaela Cupesi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice
- (2009) Xiaochang Zhang et al. NEURON
- Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization
- (2009) K. J. Roux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A perinuclear actin cap regulates nuclear shape
- (2009) Shyam B. Khatau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-precision structural analysis of subnuclear complexes in fixed and live cells via spatially modulated illumination (SMI) microscopy
- (2008) Jürgen Reymann et al. CHROMOSOME RESEARCH
- The nuclear envelope as an integrator of nuclear and cytoplasmic architecture
- (2008) Melissa Crisp et al. FEBS LETTERS
- Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice
- (2008) M. J. Puckelwartz et al. HUMAN MOLECULAR GENETICS
- Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms
- (2008) Patryk Konieczny et al. JOURNAL OF CELL BIOLOGY
- Mechanotransduction gone awry
- (2008) Diana E. Jaalouk et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
- (2008) Ning Wang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy
- (2008) L. Schermelleh et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started