Unravelling a new mechanism linking actin polymerization and gene transcription

Pro-senescence therapy for hepatocellular carcinoma

(2016) Susanne Muehlich et al.   Aging-US

MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development

(2015) P. Costello et al.   BLOOD

Genome-wide RNAi screen for nuclear actin reveals a network of cofilin regulators

(2015) J. Dopie et al.   JOURNAL OF CELL SCIENCE

Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration

(2015) Philipp Kircher et al.   Science Signaling

Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration

(2015) Philipp Kircher et al.   Science Signaling

The core and conserved role of MAL is homeostatic regulation of actin levels

(2014) L. Salvany et al.   GENES & DEVELOPMENT

Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response

(2014) X. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis

(2013) Matthias Samwer et al.   EMBO JOURNAL

Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence

(2013) Veronika Hampl et al.   EMBO Molecular Medicine

Analysis of nuclear actin by overexpression of wild-type and actin mutant proteins

(2013) Enikö Kokai et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Nuclear Actin Network Assembly by Formins Regulates the SRF Coactivator MAL

(2013) C. Baarlink et al.   SCIENCE

MAL/MRTF-A controls migration of non-invasive cells by upregulation of cytoskeleton-associated proteins

(2012) Laura Leitner et al.   JOURNAL OF CELL SCIENCE

Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription

(2012) W. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

(2011) Wendy Huang et al.   NATURE

The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1

(2011) S Muehlich et al.   ONCOGENE

RefilinB (FAM101B) targets FilaminA to organize perinuclear actin networks and regulates nuclear shape

(2011) O. Gay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development

(2010) M. H. Mokalled et al.   DEVELOPMENT

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A

(2010) Rafał Pawłowski et al.   EMBO JOURNAL

Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4

(2010) M. Kumeta et al.   JOURNAL OF CELL SCIENCE

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Cytoskeleton Protein Filamin-A Is Required for an Efficient Recombinational DNA Double Strand Break Repair

(2009) J. Yue et al.   CANCER RESEARCH

Comparative protein expression profiles of hilar and peripheral hepatic cholangiocarcinomas

(2009) Nathalie Guedj et al.   JOURNAL OF HEPATOLOGY

A Nuclear Actin Function Regulates Neuronal Motility by Serum Response Factor-Dependent Gene Transcription

(2009) S. Stern et al.   JOURNAL OF NEUROSCIENCE

Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression

(2009) Christine Stritt et al.   NATURE NEUROSCIENCE

Serum-Induced Phosphorylation of the Serum Response Factor Coactivator MKL1 by the Extracellular Signal-Regulated Kinase 1/2 Pathway Inhibits Its Nuclear Localization

(2008) S. Muehlich et al.   MOLECULAR AND CELLULAR BIOLOGY