Targeted Ablation of Nesprin 1 and Nesprin 2 from Murine Myocardium Results in Cardiomyopathy, Altered Nuclear Morphology and Inhibition of the Biomechanical Gene Response

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins

(2012) Brian A. Sosa et al.   CELL

Structural insights into SUN-KASH complexes across the nuclear envelope

(2012) Wenjia Wang et al.   CELL RESEARCH

LINC complex alterations in DMD and EDMD/CMT fibroblasts

(2012) Surayya Taranum et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mechanosensitive mechanisms in transcriptional regulation

(2012) Akiko Mammoto et al.   JOURNAL OF CELL SCIENCE

Computational image analysis of nuclear morphology associated with various nuclear-specific aging disorders

(2012) Siwon Choi et al.   Nucleus

Thymosin Beta 4 Is Dispensable for Murine Cardiac Development and Function

(2011) Indroneal Banerjee et al.   CIRCULATION RESEARCH

Nuclear lamins and laminopathies

(2011) Howard J. Worman   JOURNAL OF PATHOLOGY

Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization

(2011) Joshua T. Morgan et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear morphology and deformation in engineered cardiac myocytes and tissues

(2010) Mark-Anthony P. Bray et al.   BIOMATERIALS

Myocardial Lineage Development

(2010) Sylvia M. Evans et al.   CIRCULATION RESEARCH

The genetics of dilated cardiomyopathy

(2010) Lisa Dellefave et al.   CURRENT OPINION IN CARDIOLOGY

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?

(2010) A. Buxboim et al.   JOURNAL OF CELL SCIENCE

Diseases of the Nuclear Envelope

(2010) H. J. Worman et al.   Cold Spring Harbor Perspectives in Biology

IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart

(2009) Indroneal Banerjee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Targeted Ablation of PINCH1 and PINCH2 From Murine Myocardium Results in Dilated Cardiomyopathy and Early Postnatal Lethality

(2009) Xingqun Liang et al.   CIRCULATION

Nesprin 1 is critical for nuclear positioning and anchorage

(2009) Jianlin Zhang et al.   HUMAN MOLECULAR GENETICS

Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections

(2009) David Razafsky et al.   JOURNAL OF CELL BIOLOGY

Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum

(2009) S. Lange et al.   JOURNAL OF CELL SCIENCE

Nesprin-1 mutations in human and murine cardiomyopathy

(2009) Megan J. Puckelwartz et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers

(2009) T. Moore-Morris et al.   MOLECULAR PHARMACOLOGY

Patterns of evolutionary conservation in the nesprin genes highlight probable functionally important protein domains and isoforms

(2008) Jennifer G. Simpson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models

(2008) Christopher M. Hale et al.   BIOPHYSICAL JOURNAL

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness

(2008) P.J. Stewart-Hutchinson et al.   EXPERIMENTAL CELL RESEARCH

Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice

(2008) M. J. Puckelwartz et al.   HUMAN MOLECULAR GENETICS