Transcription upregulation via force-induced direct stretching of chromatin

Extracellular rigidity sensing by talin isoform-specific mechanical linkages

(2015) Katharina Austen et al.   NATURE CELL BIOLOGY

Systems Mechanobiology: Tension-Inhibited Protein Turnover Is Sufficient to Physically Control Gene Circuits

(2014) P.C. Dave P. Dingal et al.   BIOPHYSICAL JOURNAL

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells

(2014) Pierre Therizols et al.   SCIENCE

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions

(2013) W. R. Legant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility

(2013) N. Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Soft fibrin gels promote selection and growth of tumorigenic cells

(2012) Jing Liu et al.   NATURE MATERIALS

Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells

(2012) Yeh-Chuin Poh et al.   Nature Communications

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions

(2010) Paul Sinclair et al.   JOURNAL OF CELL BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Large-scale chromatin structure of inducible genes: transcription on a condensed, linear template

(2009) Yan Hu et al.   JOURNAL OF CELL BIOLOGY

Rapid Activation of Rac GTPase in Living Cells by Force Is Independent of Src

(2009) Yeh-Chuin Poh et al.   PLoS One

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors

(2008) M. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid signal transduction in living cells is a unique feature of mechanotransduction

(2008) S. Na et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA