Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation

Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation

(2015) Yosef Gruenbaum et al.   Annual Review of Biochemistry

Nuclear mechanotransduction: Forcing the nucleus to respond

(2015) Christophe Guilluy et al.   Nucleus

Nuclear mechanotransduction: Forcing the nucleus to respond

(2015) Christophe Guilluy et al.   Nucleus

Characterization of Unfolding Mechanism of Human Lamin A Ig Fold by Single-Molecule Force Spectroscopy—Implications in EDMD

(2014) Manindra Bera et al.   BIOCHEMISTRY

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

(2014) Amnon Buxboim et al.   CURRENT BIOLOGY

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

(2014) Peter Meinke et al.   PLoS Genetics

Reversal of age-dependent nuclear morphology by inhibition of prenylation does not affect lifespan inCaenorhabditis elegans

(2014) Daniel Z. Bar et al.   Nucleus

When Lamins Go Bad: Nuclear Structure and Disease

(2013) Katherine H. Schreiber et al.   CELL

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

(2013) Monika Zwerger et al.   HUMAN MOLECULAR GENETICS

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

(2013) J.-W. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

The nuclear envelope proteome differs notably between tissues

(2012) Nadia Korfali et al.   Nucleus

Nuclear Mechanics in Disease

(2011) Monika Zwerger et al.   Annual Review of Biomedical Engineering

Prelamin A-mediated nuclear envelope dynamics in normal and laminopathic cells: Figure 1

(2011) Giovanna Lattanzi   BIOCHEMICAL SOCIETY TRANSACTIONS

Nuclear lamins and laminopathies

(2011) Howard J. Worman   JOURNAL OF PATHOLOGY

Structural and physiological phenotypes of disease-linked lamin mutations in C. elegans

(2011) Erin M. Bank et al.   JOURNAL OF STRUCTURAL BIOLOGY

A laminopathic mutation disrupting lamin filament assembly causes disease-like phenotypes in Caenorhabditis elegans

(2011) Erin M. Bank et al.   MOLECULAR BIOLOGY OF THE CELL

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons

(2011) Catherine Coffinier et al.   MOLECULAR BIOLOGY OF THE CELL

Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis

(2011) Rachel Barkan et al.   MOLECULAR BIOLOGY OF THE CELL

Caenorhabditis elegansas a model system for studying the nuclear lamina and laminopathic diseases

(2011) Erin M. Bank et al.   Nucleus

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria

(2010) Lidia Hernandez et al.   DEVELOPMENTAL CELL

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

(2010) E. S. Folker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamins

(2010) T. Dechat et al.   Cold Spring Harbor Perspectives in Biology

Morphological Analysis of 13 LMNA Variants Identified in a Cohort of 324 Unrelated Patients With Idiopathic or Familial Dilated Cardiomyopathy

(2009) Jason Cowan et al.   Circulation-Cardiovascular Genetics

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

(2009) Farhana Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A nuclear-envelope bridge positions nuclei and moves chromosomes

(2009) D. A. Starr   JOURNAL OF CELL SCIENCE

A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization

(2009) P. Taimen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models

(2008) Christopher M. Hale et al.   BIOPHYSICAL JOURNAL

The nuclear envelope as an integrator of nuclear and cytoplasmic architecture

(2008) Melissa Crisp et al.   FEBS LETTERS

Analysis of Prelamin A Biogenesis Reveals the Nucleus to be a CaaX Processing Compartment

(2008) Jemima Barrowman et al.   MOLECULAR BIOLOGY OF THE CELL