cGAS surveillance of micronuclei links genome instability to innate immunity
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
cGAS surveillance of micronuclei links genome instability to innate immunity
Authors
Keywords
-
Journal
NATURE
Volume 548, Issue 7668, Pages 461-465
Publisher
Springer Nature
Online
2017-07-20
DOI
10.1038/nature23449
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment
- (2017) Kristina Kirschner et al. Cell Reports
- Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
- (2016) Karen J Mackenzie et al. EMBO JOURNAL
- Recognition of Endogenous Nucleic Acids by the Innate Immune System
- (2016) Axel Roers et al. IMMUNITY
- RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice
- (2016) Vladislav Pokatayev et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The role of cGAS in innate immunity and beyond
- (2016) Andrea Ablasser et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
- (2016) Qi Chen et al. NATURE IMMUNOLOGY
- ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
- (2016) M. Raab et al. SCIENCE
- Nuclear envelope rupture and repair during cancer cell migration
- (2016) C. M. Denais et al. SCIENCE
- Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
- (2016) Tianli Xia et al. Cell Reports
- Chromothripsis and Kataegis Induced by Telomere Crisis
- (2015) John Maciejowski et al. CELL
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- Activation and Regulation of DNA-Driven Immune Responses
- (2015) Søren R. Paludan MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Chromothripsis from DNA damage in micronuclei
- (2015) Cheng-Zhong Zhang et al. NATURE
- Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
- (2015) Daxing Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Viruses transfer the antiviral second messenger cGAMP between cells
- (2015) A. Bridgeman et al. SCIENCE
- DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway
- (2015) L. Lau et al. SCIENCE
- Central Role of ULK1 in Type I Interferon Signaling
- (2015) Diana Saleiro et al. Cell Reports
- Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells
- (2015) Yu J. Shen et al. Cell Reports
- A high-throughput in vivo micronucleus assay for genome instability screening in mice
- (2015) Gabriel Balmus et al. Nature Protocols
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
- (2014) Seng-Ryong Woo et al. IMMUNITY
- Breaching the nuclear envelope in development and disease
- (2014) Emily Hatch et al. JOURNAL OF CELL BIOLOGY
- Bayesian approach to single-cell differential expression analysis
- (2014) Peter V Kharchenko et al. NATURE METHODS
- Full-length RNA-seq from single cells using Smart-seq2
- (2014) Simone Picelli et al. Nature Protocols
- Inflammation-driven carcinogenesis is mediated through STING
- (2014) Jeonghyun Ahn et al. Nature Communications
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy
- (2014) Yuk Yuen Lan et al. Cell Reports
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei
- (2013) Emily M. Hatch et al. CELL
- Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
- (2013) Xin Li et al. IMMUNITY
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
- (2013) John W. Schoggins et al. NATURE
- The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote
- (2013) Yang Liao et al. NUCLEIC ACIDS RESEARCH
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
- (2012) Martin A.M. Reijns et al. CELL
- Chromosomal instability and cancer: a complex relationship with therapeutic potential
- (2012) Samuel F. Bakhoum et al. JOURNAL OF CLINICAL INVESTIGATION
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Analysis of the cellular uptake and nuclear delivery of insulin-like growth factor binding protein-3 in human osteosarcoma cells
- (2011) Lucia Micutkova et al. INTERNATIONAL JOURNAL OF CANCER
- Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures
- (2010) Catherine Naughton et al. MOLECULAR CELL
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Coordination of dual incision and repair synthesis in human nucleotide excision repair
- (2009) Lidija Staresincic et al. EMBO JOURNAL
- Genome instability: a mechanistic view of its causes and consequences
- (2008) Andrés Aguilera et al. NATURE REVIEWS GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now