A variety of death modes of neutrophils and their role in the etiology of autoimmune diseases

Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4)

(2023) Abby D Ivey et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The role of neutrophil extracellular traps and proinflammatory damage-associated molecular patterns in idiopathic inflammatory myopathies

(2023) Wenlan Ma et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Antibodies against neutrophil extracellular traps (NETs) potentiate clinical performance of anti-double-stranded DNA antibodies in systemic lupus erythematosus

(2023) Minghua Zhan et al.   CLINICAL IMMUNOLOGY

Neutrophil extracellular trap formation in anti-neutrophil cytoplasmic antibody-associated and large-vessel vasculitis

(2023) Despina Michailidou et al.   CLINICAL IMMUNOLOGY

Autophagy in a Nutshell

(2023) Oren Shatz et al.   FEBS LETTERS

Galectin-3 Mediates NETosis and Acts as an Autoantigen in Systemic Lupus Erythematosus-Associated Diffuse Alveolar Haemorrhage

(2023) Shih-Yao Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transient receptor potential melastatin 2 regulates neutrophil extracellular traps formation and delays resolution of neutrophil-driven sterile inflammation

(2023) Xue Cao et al.   Journal of Inflammation-London

The intricate relationship between autoimmunity disease and neutrophils death patterns: a love-hate story

(2023) Ziwei Zhang et al.   APOPTOSIS

NETosis promotes chronic inflammation and fibrosis in systemic lupus erythematosus and COVID-19

(2023) Huiqing Lin et al.   CLINICAL IMMUNOLOGY

Molecular signature of neutrophil extracellular trap mediating disease module in idiopathic inflammatory myopathy

(2023) Su-Jin Moon et al.   JOURNAL OF AUTOIMMUNITY

Ferroptosis of immune cells in the tumor microenvironment

(2023) Rina Kim et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation

(2023) Germana Lentini et al.   Cell Reports Medicine

Neutrophils Contribute to ER Stress in Lung Epithelial Cells in the Pristane-Induced Diffuse Alveolar Hemorrhage Mouse Model

(2022) Gantsetseg Tumurkhuu et al.   Frontiers in Immunology

What Is Rheumatoid Arthritis?

(2022) Melanie H. Smith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps

(2022) Brendan Antiochos et al.   eLife

Indicator of Inflammation and NETosis—Low-Density Granulocytes as a Biomarker of Autoimmune Hepatitis

(2022) Weronika Domerecka et al.   Journal of Clinical Medicine

Autophagy in lupus nephritis: A delicate balance between regulation and disease

(2022) Manuel Alfredo Podestà et al.   AUTOIMMUNITY REVIEWS

IAPs antagonist SM164 ameliorates experimental MPO-ANCA-associated vasculitis via enhancing fatty acid oxidation in neutrophils

(2022) Luo-Yi Wang et al.   RHEUMATOLOGY

Serum extracellular traps associate with the activation of myeloid cells in SLE patients with the low level of anti-DNA antibodies

(2022) Norio Hanata et al.   Scientific Reports

Ferroptosis of tumour neutrophils causes immune suppression in cancer

(2022) Rina Kim et al.   NATURE

Caspase-8 activation in neutrophils facilitates autoimmune kidney vasculitis through regulating CD4+ effector memory T cells

(2022) Jian Hu et al.   Frontiers in Immunology

Rheumatoid Arthritis Synovial Fluid Neutrophils Drive Inflammation Through Production of Chemokines, Reactive Oxygen Species, and Neutrophil Extracellular Traps

(2021) Helen L. Wright et al.   Frontiers in Immunology

The cytosolic DNA sensor cGAS recognizes neutrophil extracellular traps

(2021) Falko Apel et al.   Science Signaling

Neutrophils: Many Ways to Die

(2021) Erandi Pérez-Figueroa et al.   Frontiers in Immunology

ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo

(2021) Hubert Hayden et al.   PLoS One

The enrichment of neutrophil extracellular traps impair the placentas of systemic lupus erythematosus through accumulating decidual NK cells

(2021) Meng Jiang et al.   Scientific Reports

RNA externalized by neutrophil extracellular traps promotes inflammatory pathways in endothelial cells

(2021) Luz P. Blanco et al.   Arthritis & Rheumatology

A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis

(2021) Caroline Grönwall et al.   Frontiers in Immunology

Neutrophil Extracellular Traps in Systemic Lupus Erythematosus Stimulate IgG2 Production From B Lymphocytes

(2021) Roberta Bertelli et al.   Frontiers in Medicine

The Neutrophil

(2021) Garth Lawrence Burn et al.   IMMUNITY

Glutathione peroxidase 4–regulated neutrophil ferroptosis induces systemic autoimmunity

(2021) Pengchong Li et al.   NATURE IMMUNOLOGY

NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFNα production in SLE patients

(2021) Spiros Georgakis et al.   JCI Insight

Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution

(2021) Lili Bao et al.   Bioactive Materials

Neutrophil extracellular traps: from physiology to pathology

(2021) Andres Hidalgo et al.   CARDIOVASCULAR RESEARCH

Neutrophil and remnant clearance in immunity and inflammation

(2021) Apurwa Singhal et al.   IMMUNOLOGY

Impact of Posttranslational Modification in Pathogenesis of Rheumatoid Arthritis: Focusing on Citrullination, Carbamylation, and Acetylation

(2021) Eui-Jong Kwon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Approaching Neutrophil Pyroptosis

(2021) Gabriel Sollberger   JOURNAL OF MOLECULAR BIOLOGY

Global epidemiology of vasculitis

(2021) Richard A. Watts et al.   Nature Reviews Rheumatology

Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Targeting TLR4 and CXCL2

(2021) Binbin Yang et al.   Frontiers in Immunology

Optimization of BCG Therapy Targeting Neutrophil Extracellular Traps, Autophagy, and miRNAs in Bladder Cancer: Implications for Personalized Medicine

(2021) Chenyu Mao et al.   Frontiers in Medicine

Autophagy and autophagy-related proteins in cancer

(2020) Xiaohua Li et al.   Molecular Cancer

Neutrophil extracellular trap-enriched supernatants carry microRNAs able to modulate TNF-α production by macrophages

(2020) Leandra Linhares-Lacerda et al.   Scientific Reports

A novel peptidylarginine deiminase 4 (PAD4) inhibitor BMS-P5 blocks formation of neutrophil extracellular traps and delays progression of multiple myeloma

(2020) Marina Li et al.   MOLECULAR CANCER THERAPEUTICS

PAD enzymes in rheumatoid arthritis: pathogenic effectors and autoimmune targets

(2020) Ashley M. Curran et al.   Nature Reviews Rheumatology

NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

(2020) Hawa Racine Thiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil heterogeneity and fate in inflamed tissues: implications for the resolution of inflammation

(2020) János G Filep et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cellular Mechanisms of NETosis

(2020) Hawa Racine Thiam et al.   Annual Review of Cell and Developmental Biology

Hydroxychloroquine inhibiting neutrophil extracellular trap formation alleviates hepatic ischemia/reperfusion injury by blocking TLR9 in mice

(2020) Sigong Zhang et al.   CLINICAL IMMUNOLOGY

RIPK3–MLKL–Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α

(2020) Xiaoliang Wang et al.   JOURNAL OF IMMUNOLOGY

How Neutrophils Meet Their End

(2020) Shelley M. Lawrence et al.   TRENDS IN IMMUNOLOGY

Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients

(2020) Svend Birkelund et al.   Clinical Proteomics

New insights regarding SNARE proteins in autophagosome-lysosome fusion

(2020) Xiaoyu Tian et al.   Autophagy

Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

(2020) Kazuaki Matoba et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MFG-E8 accelerates wound healing in diabetes by regulating “NLRP3 inflammasome-neutrophil extracellular traps” axis

(2020) Wei Huang et al.   Cell Death Discovery

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response

(2019) Ramon G. Bonegio et al.   JOURNAL OF IMMUNOLOGY

Receptor interacting protein kinase 3 (RIP3) regulates iPSCs generation through modulating cell cycle progression genes

(2019) Ahmad Al-Moujahed et al.   Stem Cell Research

Activated neutrophil carbamylates albumin via the release of myeloperoxidase and reactive oxygen species regardless of NETosis.

(2019) Shuichiro Nakabo et al.   Modern Rheumatology

Neutrophil extracellular traps are associated with the pathogenesis of diffuse alveolar hemorrhage in murine lupus

(2019) Pierre-André Jarrot et al.   JOURNAL OF AUTOIMMUNITY

Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion

(2019) Ajitha Thanabalasuriar et al.   Cell Host & Microbe

Neutrophil extracellular traps generation and degradation in patients with granulomatosis with polyangiitis and systemic lupus erythematosus

(2019) Michal Przemyslaw Pruchniak et al.   AUTOIMMUNITY

Neutrophil extracellular traps (NET) induced by different stimuli: A comparative proteomic analysis

(2019) Andrea Petretto et al.   PLoS One

A Neutrophil Activation Biomarker Panel in Prognosis and Monitoring of Patients with Rheumatoid Arthritis

(2019) Mary Bach et al.   Arthritis & Rheumatology

Extracellular DNA NET-Works With Dire Consequences for Health

(2019) Nicoletta Sorvillo et al.   CIRCULATION RESEARCH

Neutrophil Extracellular Traps in Tissue and Periphery in Juvenile Dermatomyositis

(2019) Bhargavi Duvvuri et al.   Arthritis & Rheumatology

Neutrophil Extracellular Trap Formation: Physiology, Pathology, and Pharmacology

(2019) Mithunan Ravindran et al.   Biomolecules

NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

(2019) Petrus Linge et al.   ANNALS OF THE RHEUMATIC DISEASES

Autophagosome-Lysosome Fusion

(2019) Péter Lőrincz et al.   JOURNAL OF MOLECULAR BIOLOGY

Neutrophil extracellular traps are a source of extracellular HMGB1 in lupus nephritis: associations with clinical and histopathological features

(2019) L P Whittall-García et al.   LUPUS

Neutrophil extracellular traps activate lung fibroblast to induce polymyositis‐related interstitial lung diseases via TLR9‐miR‐7‐Smad2 pathway

(2019) Sigong Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A reverse translational study on the effect of rituximab, rituximab plus belimumab, or bortezomib on the humoral autoimmune response in SLE

(2019) Laura S van Dam et al.   RHEUMATOLOGY

Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging

(2018) Siu Ling Wong et al.   FASEB JOURNAL

Granulomatosis with polyangiitis (Wegener granulomatosis): A proteinase-3 driven disease?

(2018) Véronique Witko-Sarsat et al.   JOINT BONE SPINE

The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus

(2018) Tineke Kraaij et al.   JOURNAL OF AUTOIMMUNITY

Netting Neutrophils Activate Autoreactive B Cells in Lupus

(2018) Nicolas Gestermann et al.   JOURNAL OF IMMUNOLOGY

Role of inflammasomes in inflammatory autoimmune rheumatic diseases

(2018) Young-Su Yi   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation

(2018) Tao-Tao Tang et al.   Cell Death & Disease

Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells

(2018) Pascale Tacnet-Delorme et al.   Frontiers in Immunology

Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation

(2018) Elmar Pieterse et al.   ANNALS OF THE RHEUMATIC DISEASES

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis

(2018) Norma Maugeri et al.   Science Translational Medicine

Development of a New Classification System for Idiopathic Inflammatory Myopathies Based on Clinical Manifestations and Myositis-Specific Autoantibodies

(2018) Kubéraka Mariampillai et al.   JAMA Neurology

REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A)

(2018) Eleni Frangou et al.   ANNALS OF THE RHEUMATIC DISEASES

Enhanced neutrophil autophagy and increased concentrations of IL-6, IL-8, IL-10 and MCP-1 in rheumatoid arthritis

(2018) Qiyuan An et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Many Ways–One Destination: Different Types of Neutrophils Death

(2018) Dorota Dąbrowska et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

De novo autoimmune hepatitis –is this different in adults compared to children?

(2018) Nanda Kerkar et al.   JOURNAL OF AUTOIMMUNITY

PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis

(2017) Sindhu Koushik et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Autophagosome Maturation and Fusion

(2017) Fulvio Reggiori et al.   JOURNAL OF MOLECULAR BIOLOGY

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

(2017) Yan G. Zhao et al.   MOLECULAR CELL

Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis

(2017) Adrian Schreiber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse stimuli engage different neutrophil extracellular trap pathways

(2017) Elaine F Kenny et al.   eLife

Redox regulation in metabolic programming and inflammation

(2017) Helen R. Griffiths et al.   Redox Biology

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?

(2016) Yuan Ying et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Advances in serological diagnostics of inflammatory myopathies

(2016) Olivier Benveniste et al.   CURRENT OPINION IN NEUROLOGY

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

(2016) Lorenzo Sborgi et al.   EMBO JOURNAL

Oxidative stress modulates the cytokine response of differentiated Th17 and Th1 cells

(2016) Thiruvaimozhi Abimannan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chronic Granulomatous Disease

(2016) Amit Rawat et al.   INDIAN JOURNAL OF PEDIATRICS

Autophagy is induced by anti-neutrophil cytoplasmic Abs and promotes neutrophil extracellular traps formation

(2016) Li-Li Sha et al.   Innate Immunity

Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming

(2016) Xiaoliang Wang et al.   JOURNAL OF IMMUNOLOGY

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

(2016) Jonathan J. Kotzin et al.   NATURE

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Human neutrophils in auto-immunity

(2016) Nathalie Thieblemont et al.   SEMINARS IN IMMUNOLOGY

Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells

(2016) Dongsheng Jiang et al.   STEM CELLS

Circulating Apoptotic Microparticles in Systemic Lupus Erythematosus Patients Drive the Activation of Dendritic Cell Subsets and Prime Neutrophils for NETosis

(2016) Jürgen Dieker et al.   Arthritis & Rheumatology

Neutrophil Extracellular Traps in ANCA-Associated Vasculitis

(2016) Daniel Söderberg et al.   Frontiers in Immunology

Systemic lupus erythematosus

(2016) Arvind Kaul et al.   Nature Reviews Disease Primers

Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs

(2015) Elisa Corsiero et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

(2015) Akilan Krishnamurthy et al.   ANNALS OF THE RHEUMATIC DISEASES

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis

(2015) S. Tang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The role of neutrophils in the pathogenesis of systemic lupus erythematosus

(2015) Carolyne K. Smith et al.   CURRENT OPINION IN RHEUMATOLOGY

Fcγand Complement Receptors and Complement Proteins in Neutrophil Activation in Rheumatoid Arthritis: Contribution to Pathogenesis and Progression and Modulation by Natural Products

(2015) Adriana Balbina Paoliello-Paschoalato et al.   Evidence-based Complementary and Alternative Medicine

Pyroptotic cell death defends against intracellular pathogens

(2015) Ine Jorgensen et al.   IMMUNOLOGICAL REVIEWS

Differential clearance mechanisms, neutrophil extracellular trap degradation and phagocytosis, are operative in systemic lupus erythematosus patients with distinct autoantibody specificities

(2015) Sudhir Kumar Chauhan et al.   IMMUNOLOGY LETTERS

Neutrophil Extracellular Trap-Related Extracellular Histones Cause Vascular Necrosis in Severe GN

(2015) S. V. R. Kumar et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling

(2015) Yves Dondelinger et al.   MOLECULAR CELL

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

(2015) Huw D Lewis et al.   Nature Chemical Biology

Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in Juvenile-onset Systemic Lupus Erythematosus

(2015) Lucy Ballantine et al.   Pediatric Rheumatology

Autophagy Is Required for Neutrophil-Mediated Inflammation

(2015) Abhisek Bhattacharya et al.   Cell Reports

Neutrophil-Related Gene Expression and Low-Density Granulocytes Associated With Disease Activity and Response to Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

(2015) Peter C. Grayson et al.   Arthritis & Rheumatology

Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

(2015) Julia Spengler et al.   Arthritis & Rheumatology

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof-of-Concept Trial of Metformin

(2015) Haiting Wang et al.   Arthritis & Rheumatology

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lprmice

(2014) Jason S Knight et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2

(2014) Carmelo Carmona-Rivera et al.   ANNALS OF THE RHEUMATIC DISEASES

Akt is essential to induce NADPH-dependent NETosis and to switch the neutrophil death to apoptosis

(2014) D. N. Douda et al.   BLOOD

The generation of neutrophils in the bone marrow is controlled by autophagy

(2014) S Rožman et al.   CELL DEATH AND DIFFERENTIATION

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

(2014) Jason S. Knight et al.   CIRCULATION RESEARCH

Acetylated histones contribute to the immunostimulatory potential of neutrophil extracellular traps in systemic lupus erythematosus

(2014) E. Pieterse et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Enhanced formation and impaired degradation of neutrophil extracellular traps in dermatomyositis and polymyositis: a potential contributor to interstitial lung disease complications

(2014) S. Zhang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The protective effect of GM-CSF on serum-induced neutrophil apoptosis in juvenile systemic lupus erythematosus patients

(2014) Direkrit Chiewchengchol et al.   CLINICAL RHEUMATOLOGY

Enhanced Formation and Disordered Regulation of NETs in Myeloperoxidase-ANCA-Associated Microscopic Polyangiitis

(2014) D. Nakazawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps

(2014) N. Maugeri et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Characterization of the impairment of the uptake of apoptotic polymorphonuclear cells by monocyte subpopulations in systemic lupus erythematosus

(2014) T P Mikołajczyk et al.   LUPUS

Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A

(2014) Anurag Kumar Gupta et al.   PLoS One

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Diagnosis, pathogenesis and treatment of myositis: recent advances

(2013) P. -O. Carstens et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

(2013) Jason S. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

Interferon-  Abrogates the Suppressive Effect of Apoptotic Cells on Dendritic Cells in an In Vitro Model of Systemic Lupus Erythematosus Pathogenesis

(2013) L. Abeler-Dorner et al.   JOURNAL OF RHEUMATOLOGY

Apport des auto-anticorps au cours des myopathies auto-immunes

(2013) Y. Allenbach et al.   REVUE NEUROLOGIQUE

Immune-Mediated Pore-Forming Pathways Induce Cellular Hypercitrullination and Generate Citrullinated Autoantigens in Rheumatoid Arthritis

(2013) V. Romero et al.   Science Translational Medicine

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Mechanisms regulating neutrophil survival and cell death

(2013) María Laura Gabelloni et al.   Seminars in Immunopathology

Role of neutrophils in systemic autoimmune diseases

(2013) Mariana J Kaplan   ARTHRITIS RESEARCH & THERAPY

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

(2012) S. Sangaletti et al.   BLOOD

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The role of endothelial-mesenchymal transition in development and pathological process

(2012) Feng Lin et al.   IUBMB LIFE

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

(2012) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Neutrophil apoptosis is associated with loss of signal regulatory protein alpha (SIRP ) from the cell surface

(2012) A. Stenberg et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Expression of Toll-like receptors and their detection of nuclear self-antigen leading to immune activation in JSLE

(2012) A. Midgley et al.   RHEUMATOLOGY

Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies

(2012) Chih Liu et al.   ARTHRITIS RESEARCH & THERAPY

Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

(2012) John S. Cho et al.   PLoS Pathogens

Peptidylarginine Deiminases Present in the Airways during Tobacco Smoking and Inflammation Can Citrullinate the Host Defense Peptide LL-37, Resulting in Altered Activities

(2011) Ola Kilsgård et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps

(2011) Nishant Dwivedi et al.   ARTHRITIS AND RHEUMATISM

Activation of hypoxia-inducible factor-1  (Hif-1 ) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

(2011) P. M. Elks et al.   BLOOD

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils

(2011) Arun K. Mankan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting Fc RI on Polymorphonuclear Cells Induces Tumor Cell Killing through Autophagy

(2011) J. E. Bakema et al.   JOURNAL OF IMMUNOLOGY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Primary biliary cirrhosis

(2011) Carlo Selmi et al.   LANCET

Autoimmune hepatitis

(2011) Giorgina Mieli-Vergani et al.   Nature Reviews Gastroenterology & Hepatology

Porphyromonas gingivalis Participates in Pathogenesis of Human Abdominal Aortic Aneurysm by Neutrophil Activation. Proof of Concept in Rats

(2011) Sandrine Delbosc et al.   PLoS One

PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection

(2011) Saskia Hemmers et al.   PLoS One

Analysis of SF and plasma cytokines provides insights into the mechanisms of inflammatory arthritis and may predict response to therapy

(2011) H. L. Wright et al.   RHEUMATOLOGY

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Regulation of Neutrophil Survival/Apoptosis by Mcl-1

(2011) Eric Milot et al.   TheScientificWorldJOURNAL

Changes in expression of membrane TNF, NF- B activation and neutrophil apoptosis during active and resolved inflammation

(2010) H. L. Wright et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Regulation of the autophagic machinery in human neutrophils

(2010) Ioannis Mitroulis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

(2010) Cristiana Guiducci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs

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RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

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Hydroxyl radical damaged Immunoglobulin G in patients with rheumatoid arthritis: Biochemical and immunological studies

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