Many Ways–One Destination: Different Types of Neutrophils Death

Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death

(2018) Hiroto Kambara et al.   Cell Reports

Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

(2018) Leonardo Iula et al.   Frontiers in Immunology

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation

(2017) Thomas Riffelmacher et al.   IMMUNITY

Aging-related Atg5 defect impairs neutrophil extracellular traps formation

(2017) Fengying Xu et al.   IMMUNOLOGY

Cigarette smoke promotes COPD by activating platelet-activating factor receptor and inducing neutrophil autophagic death in mice

(2017) Xiao-Xi Lv et al.   Oncotarget

Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin

(2017) Jyaysi Desai et al.   Scientific Reports

Different procedures of diphenyleneiodonium chloride addition affect neutrophil extracellular trap formation

(2016) Magdalena Ostafin et al.   ANALYTICAL BIOCHEMISTRY

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

(2016) Lorenzo Sborgi et al.   EMBO JOURNAL

Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming

(2016) Xiaoliang Wang et al.   JOURNAL OF IMMUNOLOGY

Francisella tularensis Modulates a Distinct Subset of Regulatory Factors and Sustains Mitochondrial Integrity to Impair Human Neutrophil Apoptosis

(2016) Jenna M. McCracken et al.   Journal of Innate Immunity

Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model

(2016) Bethany M. Biron et al.   Journal of Innate Immunity

Neutrophil pyroptosis mediates pathology of P. aeruginosa lung infection in the absence of the NADPH oxidase NOX2

(2016) J-C Ryu et al.   Mucosal Immunology

Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils

(2016) Simone Wicki et al.   Cell Death & Disease

Macroautophagy is essential for killing of intracellularBurkholderia pseudomalleiin human neutrophils

(2015) Darawan Rinchai et al.   Autophagy

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling

(2015) Jyaysi Desai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NET formation can occur independently of RIPK3 and MLKL signaling

(2015) Poorya Amini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species

(2015) Halla Björnsdottir et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pyroptotic cell death defends against intracellular pathogens

(2015) Ine Jorgensen et al.   IMMUNOLOGICAL REVIEWS

Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+Efflux

(2015) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Is Required for Neutrophil-Mediated Inflammation

(2015) Abhisek Bhattacharya et al.   Cell Reports

Potential role of autophagy in the bactericidal activity of human PMNs forBacillus anthracis

(2015) Girish Ramachandran et al.   Pathogens and Disease

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof-of-Concept Trial of Metformin

(2015) Haiting Wang et al.   Arthritis & Rheumatology

Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites

(2015) Natalia C. Rochael et al.   Scientific Reports

The generation of neutrophils in the bone marrow is controlled by autophagy

(2014) S Rožman et al.   CELL DEATH AND DIFFERENTIATION

Expression of selected proteins of the extrinsic and intrinsic pathways of apoptosis in human leukocytes exposed to N-nitrosodimethylamine

(2014) A Iwaniuk et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

(2014) Marc Röhm et al.   INFECTION AND IMMUNITY

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

(2014) Kathleen D. Metzler et al.   Cell Reports

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

(2014) Kaiwen W. Chen et al.   Cell Reports

Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy

(2013) Asako Itakura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

(2013) Julian I. Borissoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An Extracellular Matrix-Based Mechanism of Rapid Neutrophil Extracellular Trap Formation in Response to Candida albicans

(2013) A. S. Byrd et al.   JOURNAL OF IMMUNOLOGY

Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release

(2013) Indira Neeli et al.   Frontiers in Immunology

Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1  

(2012) A. M. McInturff et al.   BLOOD

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

(2012) Konstantinos Kambas et al.   PLoS One

Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

(2012) John S. Cho et al.   PLoS Pathogens

Peculiarities of cell death mechanisms in neutrophils

(2011) B Geering et al.   CELL DEATH AND DIFFERENTIATION

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils

(2011) Arun K. Mankan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Neisseria gonorrhoeae-Mediated Inhibition of Apoptotic Signalling in Polymorphonuclear Leukocytes

(2011) Adrienne Chen et al.   INFECTION AND IMMUNITY

Toxoplasma gondii Triggers Release of Human and Mouse Neutrophil Extracellular Traps

(2011) Delbert S. Abi Abdallah et al.   INFECTION AND IMMUNITY

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inflammation-Associated Autophagy-Related Programmed Necrotic Death of Human Neutrophils Characterized by Organelle Fusion Events

(2011) C. C. Mihalache et al.   JOURNAL OF IMMUNOLOGY

Rac2 is required for the formation of neutrophil extracellular traps

(2011) Michael Byung H. Lim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1

(2011) Ben A. Croker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil clearance: when the party is over, clean-up begins

(2011) Donna L. Bratton et al.   TRENDS IN IMMUNOLOGY

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Regulation of the autophagic machinery in human neutrophils

(2010) Ioannis Mitroulis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease

(2010) Sarah Fox et al.   Journal of Innate Immunity

Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis

(2010) Ramona L. McCaffrey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptidylarginine deiminase 4 and citrullination in health and disease

(2009) Consuelo Anzilotti et al.   AUTOIMMUNITY REVIEWS

Restoration of NET formation by gene therapy in CGD controls aspergillosis

(2009) M. Bianchi et al.   BLOOD

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Reprogramming of a subpopulation of human blood neutrophils by prolonged exposure to cytokines

(2009) Arpita Chakravarti et al.   LABORATORY INVESTIGATION

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Neutrophil apoptosis and the resolution of infection

(2008) Adam D. Kennedy et al.   IMMUNOLOGIC RESEARCH