A reverse translational study on the effect of rituximab, rituximab plus belimumab, or bortezomib on the humoral autoimmune response in SLE

Neutrophil extracellular trap formation is intrinsically distinct in ANCA ‐associated vasculitis and systemic lupus erythematosus

(2019) Laura S. van Dam et al.   Arthritis & Rheumatology

Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors

(2018) Tobias Alexander et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach

(2018) Christopher M. Tipton et al.   IMMUNOLOGICAL REVIEWS

The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus

(2018) Tineke Kraaij et al.   JOURNAL OF AUTOIMMUNITY

B-cell therapy in lupus nephritis: an overview

(2018) Salem Almaani et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A novel method for high-throughput detection and quantification of neutrophil extracellular traps reveals ROS-independent NET release with immune complexes

(2016) Tineke Kraaij et al.   AUTOIMMUNITY REVIEWS

Plasma cells as an innovative target in autoimmune disease with renal manifestations

(2016) Falk Hiepe et al.   Nature Reviews Nephrology

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

(2015) Tobias Alexander et al.   ANNALS OF THE RHEUMATIC DISEASES

A volcanic explosion of autoantibodies in systemic lupus erythematosus: A diversity of 180 different antibodies found in SLE patients

(2015) Gal Yaniv et al.   AUTOIMMUNITY REVIEWS

Anti-C1q autoantibodies from systemic lupus erythematosus patients activate the complement system via both the classical and lectin pathways

(2015) Sophia Thanei et al.   CLINICAL IMMUNOLOGY

Reactivity in ELISA with DNA-loaded nucleosomes in patients with proliferative lupus nephritis

(2015) Jürgen Dieker et al.   MOLECULAR IMMUNOLOGY

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

(2015) Christopher M Tipton et al.   NATURE IMMUNOLOGY

Differential effects of cyclophosphamide and mycophenolate mofetil on cellular and serological parameters in patients with systemic lupus erythematosus

(2015) Till Fassbinder et al.   ARTHRITIS RESEARCH & THERAPY

Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids

(2013) Marie B Condon et al.   ANNALS OF THE RHEUMATIC DISEASES

Autoantibodies from long-lived ‘memory’ plasma cells of NZB/W mice drive immune complex nephritis

(2013) Qingyu Cheng et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunoserological parameters in SLE: high-avidity anti-dsDNA detected by ELISA are the most closely associated with the disease activity

(2013) Sladjana Andrejevic et al.   CLINICAL RHEUMATOLOGY

Immune Complex Signatures of Patients with Active and Inactive SLE Revealed by Multiplex Protein Binding Analysis on Antigen Microarrays

(2012) Krisztián Papp et al.   PLoS One

B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels

(2012) Mark N. Lazarus et al.   RHEUMATOLOGY

B cell biomarkers of rituximab responses in systemic lupus erythematosus

(2011) Edward M. Vital et al.   ARTHRITIS AND RHEUMATISM

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus

(2010) C. C. van Bavel et al.   ANNALS OF THE RHEUMATIC DISEASES

Simultaneous detection of anti-C1q and anti-double stranded DNA autoantibodies in lupus nephritis: predictive value for renal flares

(2010) A Matrat et al.   LUPUS

Effect of long-term belimumab treatment on b cells in systemic lupus erythematosus: Extension of a phase II, double-blind, placebo-controlled, dose-ranging study

(2009) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

Influence of race/ethnicity on response to lupus nephritis treatment: the ALMS study

(2009) David Isenberg et al.   RHEUMATOLOGY

Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis

(2009) Maria Rehnberg et al.   ARTHRITIS RESEARCH & THERAPY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE